Results 321 to 330 of about 9,860,660 (392)

CellOntologyMapper: Consensus mapping of cell type annotation

iMetaOmics, EarlyView.
CellOntologyMapper automates the standardization of cell type annotations in single‐cell RNA‐seq by mapping user‐defined names to the Cell Ontology (CL) and Cell Taxonomy (CT). The framework constructs a comprehensive embedding database of 19,381 curated cell types using sentence transformers, large language models, and synonym expansion.
Zehua Zeng, Xuehai Wang, Hongwu Du, Cencan Xing   +3 more
wiley   +1 more source

Advances in Precision Therapeutics and Gene Therapy Applications for Retinal Diseases: Impact and Future Directions. [PDF]

Genes (Basel)
AlEissa MM, Alhawsawi AA, Alonazi R, Magharbil E, Aljahdali A, AlBalawi HB, Alali NM, Hameed S, Abu-Amero KK, Magliyah MS.   +9 more
europepmc   +1 more source

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

Interdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui, Jie Gao, Tianchang Tao, Peng Wang, Zhihao Huang, Yuyang She, Jiajie Li, Jingwan Su, Zhe Lu, Jianchao Qiao, Song Wang, Xiaodong Sun, Mohan Li   +12 more
wiley   +1 more source

Proteomics approach identifies aqueous humor biomarkers in retinal diseases. [PDF]

Commun Med (Lond)
Huang K, Schofield C, Nguy T, Dere R, Wolowski V, Siebourg-Polster J, Dieckmann A, Garweg JG, Chang M, Honigberg L, Hackney J, Indjeian VB.   +11 more
europepmc   +1 more source

Capture of adeno‐associated viruses from clarified lysate by continuous flow ultracentrifugation: a comparative study of iodixanol and sucrose gradients

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Adeno‐Associated Virus vectors are widely used in gene therapy due to their safety and efficacy. Despite the interest in their therapeutical application, AAV purification remains a significant challenge. Density gradient ultracentrifugation using cesium chloride, sucrose, or iodixanol gradients are common methods for AAV ...
Sabrina Leigheb, Maral Rahimzadeh, Nikolaus Virgolini, Aida Tleuova, Mahbod Mousavian, Astrid Dürauer, Patricia Pereira Aguilar   +6 more
wiley   +1 more source

Author Correction: Proteomics approach identifies aqueous humor biomarkers in retinal diseases. [PDF]

Commun Med (Lond)
Huang K, Schofield C, Nguy T, Dere R, Wolowski V, Siebourg-Polster J, Dieckmann A, Garweg JG, Chang M, Honigberg L, Hackney J, Indjeian VB.   +11 more
europepmc   +1 more source

Deep Learning Integration in Optical Microscopy: Advancements and Applications

Microscopy Research and Technique, EarlyView.
It explores the integration of DL into optical microscopy, focusing on key applications including image classification, segmentation, and computational reconstruction. ABSTRACT Optical microscopy is a cornerstone imaging technique in biomedical research, enabling visualization of subcellular structures beyond the resolution limit of the human eye ...
Pottumarthy Venkata Lahari, Sagnika Dutta, H. Deeksha, Samreen A. Patel, Budheswar Dehury, Nirmal Mazumder   +5 more
wiley   +1 more source

Next-generation phenotyping of inherited retinal diseases from multimodal imaging with Eye2Gene. [PDF]

Nat Mach Intell
Pontikos N, Woof WA, Lin S, Ghoshal B, Mendes BS, Veturi A, Nguyen Q, Javanmardi B, Georgiou M, Hustinx A, Ibarra-Arellano MA, Moghul I, Liu Y, Pfau K, Pfau M, Shah M, Yu J, Al-Khuzaei S, Wagner SK, Daich Varela M, Cabral de Guimarães TA, Sen S, Naik G, Sumodhee D, Fu DJ, Kabiri N, Furman J, Liefers B, Lee AY, De Silva SR, Marques C, Motta F, Fujinami-Yokokawa Y, Hardcastle AJ, Arno G, Lorenz B, Herrmann P, Fujinami K, Sallum J, Madhusudhan S, Downes SM, Holz FG, Balaskas K, Webster AR, Mahroo OA, Krawitz PM, Michaelides M.   +46 more
europepmc   +1 more source

Two‐dimensional materials for next‐generation biosensors

Journal of Intelligent Medicine, EarlyView.
Abstract Since the revolutionary breakthrough in the successful isolation and characterization of graphene in 2004, the field of two‐dimensional materials has undergone a major transformation. This pivotal advancement not only confirmed the unique ability of atomically thin layers to confine charge carriers within a two‐dimensional plane but also ...
Jiayi Liu, Xiaolin Guo, Xiaoyu Mu
wiley   +1 more source

Artificial intelligence-enabled profiling of overlapping retinal disease distribution for ocular diagnosis

S. Sundararajan, R Harikrishnan, Harshita Gupta   +2 more
openalex   +2 more sources