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Gene therapy for inherited retinal diseases: progress and possibilities
Clinical and experimental optometry, 2021Inherited retinal diseases (IRDs) comprise a heterogeneous group of genetic disorders affecting the retina. Caused by mutations in over 300 genes, IRDs result in visual impairment due to dysfunction and degeneration of photoreceptors, retinal pigment ...
Monica L Hu +6 more
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Expert opinion on therapeutic targets, 2022
Introduction Several approaches have been investigated for treating wet age-related macular degeneration (w-AMD), diabetic macular edema (DME) and retinal vein occlusions (RVOs).
L. Ferro Desideri +2 more
semanticscholar +1 more source
Introduction Several approaches have been investigated for treating wet age-related macular degeneration (w-AMD), diabetic macular edema (DME) and retinal vein occlusions (RVOs).
L. Ferro Desideri +2 more
semanticscholar +1 more source
New England Journal of Medicine, 1978
RETINAL vascular diseases are important to the internist, for they frequently represent manifestations of systemic disorders, and to the ophthalmologist because they are major causes of visual impa...
H, Dorghy, D, Toussaint
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RETINAL vascular diseases are important to the internist, for they frequently represent manifestations of systemic disorders, and to the ophthalmologist because they are major causes of visual impa...
H, Dorghy, D, Toussaint
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Occupational Health Nursing, 1983
The eye can be affected by obstructive phenomena within large vessels, such as the corotid arteries, as well as in the ophthalmic artery, central retinal artery, and branch retinal arteries. The visual impairment seen with central retinal vein obstruction usually occurs over a period of days to weeks, and although vision improves spontaneously in some ...
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The eye can be affected by obstructive phenomena within large vessels, such as the corotid arteries, as well as in the ophthalmic artery, central retinal artery, and branch retinal arteries. The visual impairment seen with central retinal vein obstruction usually occurs over a period of days to weeks, and although vision improves spontaneously in some ...
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Current Opinion in Ophthalmology, 2008
This article reports recent advances in the diagnosis, genetic analysis, and treatment of hereditary retinal disease.Clinicians and scientists continue to reveal the relationship between phenotype and genotype in hereditary retinal diseases. Persistent investigation and progressive technology are advancing the efficiency of mutation discovery.
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This article reports recent advances in the diagnosis, genetic analysis, and treatment of hereditary retinal disease.Clinicians and scientists continue to reveal the relationship between phenotype and genotype in hereditary retinal diseases. Persistent investigation and progressive technology are advancing the efficiency of mutation discovery.
openaire +2 more sources
EyeDeep-Net: a multi-class diagnosis of retinal diseases using deep neural network
Neural computing & applications (Print), 2023N. Sengar +3 more
semanticscholar +1 more source
2015
The phenotypic presentation of retinal diseases is typically underpinned by the presence of genetic variation represented by either polymorphic changes, mutations, copy number variations or epigenetic changes. Retinal dystrophies can broadly be divided into two forms, either monogenic (single-gene) or complex (multifactorial) diseases.
Moeen, Riaz, Paul N, Baird
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The phenotypic presentation of retinal diseases is typically underpinned by the presence of genetic variation represented by either polymorphic changes, mutations, copy number variations or epigenetic changes. Retinal dystrophies can broadly be divided into two forms, either monogenic (single-gene) or complex (multifactorial) diseases.
Moeen, Riaz, Paul N, Baird
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Crohn's Disease and Retinal Vascular Disease
American Journal of Ophthalmology, 1990Patients with Crohn's disease may manifest extraintestinal findings including ocular involvement. We treated two patients with Crohn's disease who manifested retinal vascular disease that may have been related to the immune nature of the underlying disease or possibly to changes in the vasculature or coagulation system.
A J, Ruby, L M, Jampol
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