Results 81 to 90 of about 29,682 (236)

The Molecular Basis of Retinal Dystrophies in Pakistan [PDF]

Genes, 2014
The customary consanguineous nuptials in Pakistan underlie the frequent occurrence of autosomal recessive inherited disorders, including retinal dystrophy (RD). In many studies, homozygosity mapping has been shown to be successful in mapping susceptibility loci for autosomal recessive inherited disease.
Khan, M.I., Azam, M., Azam, M., Ajmal, M., Collin, R.W.J., Collin, R.W.J., den Hollander, A.I., den Hollander, A.I., den Hollander, A.I., den Hollander, A.I., den Hollander, A.I., den Hollander, A.I., Cremers, F.P.M., Cremers, F.P.M., Qamar, R.   +14 more
openaire   +3 more sources

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

Inherited retinal dystrophies [PDF]

Paediatrics and Child Health, 2020
Abstract Inherited retinal dystrophies (IRD) are a diverse group of progressive blinding genetic diseases that can present from birth through to late middle age. Symptoms include loss of night vision, visual field, colour, and central acuity. Sophisticated imaging modalities and electrophysiology permit genotype–phenotype correlations.
openaire   +1 more source

The oscillatory response of the electroretinogram and neuronal adaptation

Acta Ophthalmologica, EarlyView.
Abstract After more than 50 years, there still remains a challenge and an interest to know more as well as extend and deepen our understanding of the small rapid wavelets, the oscillatory potentials (OPs), of the electroretinogram (ERG) and the neuronal adaptation of the retina.
Lillemor Wachtmeister, Anders Eklund
wiley   +1 more source

Minocycline and bone marrow–derived mononuclear cells as potential therapeutics for hereditary retinal degenerations

Acta Ophthalmologica, EarlyView.
Abstract Purpose To assess in Royal College of Surgeons (RCS) rats if the combination of two previously documented neuroprotective strategies: minocycline administration and bone marrow–derived mononuclear cells (BM‐MNCs) intravitreal transplantation, offers enhanced neuroprotection compared with each treatment alone.
Alba Videla‐Ristol, Ana Martínez‐Vacas, David García‐Bernal, Manuel Vidal‐Sanz, María Paz Villegas‐Pérez, Diego García‐Ayuso, Johnny Di Pierdomenico   +6 more
wiley   +1 more source

Doyne honeycomb retinal dystrophy – functional improvement following subthreshold nanopulse laser treatment: a case report

Journal of Medical Case Reports, 2019
Background Based on phenotypic similarities between age-related macular degeneration and the autosomal disorder Doyne honeycomb retinal dystrophy, we report on a single nanolaser treatment of a patient with genotype Doyne honeycomb retinal dystrophy ...
Andrea Cusumano, Benedetto Falsini, Emiliano Giardina, Raffaella Cascella, Jacopo Sebastiani, John Marshall   +5 more
doaj   +1 more source

Revised Swedish visual field standards for a driver's licence: Threshold perimetry as a predictor of eligibility according to the current Swedish and current Norwegian suprathreshold standards

Acta Ophthalmologica, EarlyView.
Abstract Purpose To explore whether threshold perimetry can predict fulfilment of the current Swedish and current Norwegian Esterman perimetry standards for Group 1 driver's licence, and differences in compliance between the former and current Swedish visual field standards.
Wid Saadi, Tomas Bro, Susanna Sagerfors
wiley   +1 more source

Clinical disorders affecting mesopic vision

, 2006
Vision in the mesopic range is affected by a number of inherited and acquired clinical disorders. We review these conditions and summarize the historical background, describing the clinical characteristics alongside the genetic basis and molecular ...
Gordon T. Plant, Plant, GT, Petzold, A, Axel Petzold   +3 more
core   +1 more source

Long-term observation of retinal dystrophy genetically diagnosed as ROSAH syndrome

JFO Open Ophthalmology
Purpose: To report a case of ROSAH syndrome (retinal dystrophy, optic nerve edema, splenomegaly, anhidrosis and headache) that was diagnosed by genetic analysis.
Sachiko Nishina, Kaoruko Torii, Hazuki Anzai, Tomoyo Yoshida, Toshinao Kawai, Maki Fukami, Hirotomo Saitsu, Yoshihiro Hotta   +7 more
doaj   +1 more source

Outer retina analysis by optical coherence tomography in cone-rod dystrophy patients

, 2013
Purpose: To analyze the outer retinal layers using spectral domain optical coherence tomography (SD-OCT) in patients with cone-rod dystrophy.Methods: The diagnosis of cone-rod dystrophy was determined by primary cone involvement or concomitant loss of ...
Sallum, Juliana Maria Ferraz [UNIFESP], Spaide, Richard F., Lima, Luiz Henrique Soares Goncalves de [UNIFESP]   +2 more
core   +1 more source