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Classification of turtle retinal ganglion cells
Journal of Neurophysiology, 19891. Receptive fields of 78 retinal ganglion cells were analyzed for their responses to moving and stationary lights that were presented under a variety of stimulus conditions. All cells were sensitive to moving stimuli, and their receptive fields often comprised excitatory and inhibitory sub-regions. 2.
J. E. Fulbrook, A. M. Granda
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Towards Retinal Ganglion Cell Regeneration
Regenerative Medicine, 2012Traumatic optic nerve injury and glaucoma are among the leading causes of incurable vision loss across the world. What is worse, neither pharmacological nor surgical interventions are significantly effective in reversing or halting the progression of vision loss.
Qisheng Tang+7 more
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Topography of pig retinal ganglion cells
Journal of Comparative Neurology, 2005AbstractIn the present work we analyzed the distribution of retinal ganglion cells (RGCs) in the pig retina. RGCs were retrogradely labeled in vivo by injecting Fluoro‐Gold into the optic nerve. RGC density and the distribution of RGCs in terms of soma size were analyzed. Different regions of the porcine retina were identified following analysis of the
Javier Ruiz-Ederra+3 more
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Peptides influence retinal ganglion cells
Neuroscience Letters, 1981Neurotensin, substance P and (D-Ala2, Met5)-enkephalinamide were iontophoresed onto ganglion cells of the amphibian retina. Substance P and neurotensin were found to be excitatory while (D-Ala2, Met5)-enkephalinamide suppressed all types of ganglion cells. These findings are consistent with a functional role for peptides in the vertebrate retina.
Evan Dick, Robert F. Miller
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Retinal Ganglion Cells and Neuroprotection for Glaucoma
Survey of Ophthalmology, 2003Neuroprotection is a therapeutic strategy directed at keeping retinal ganglion cells (RGCs) alive and functional. This article discusses three commonly asked questions about neuroprotection and attempts to answer them in the context of our current understanding of the pathophysiology of RGC loss in glaucomatous optic neuropathy.
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The responses of the retinal ganglion cells of the frog
Vision Research, 1975Abstract Three groupsofunitswere recorded from theretinaof Rana esculenta . These were: (a)Units which responded to a square wave modulated light stimulus and these were of three types: ON units, ON-OFF units and OFF units. Stimulus-response curves for both a stimulating central spot and an annulus were constructed and the effects of increasing ...
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Correlated firing of retinal ganglion cells
Trends in Neurosciences, 1989Even in the absence of visual stimulation, retinal ganglion cells have a substantial maintained discharge. This maintained discharge is not generated independently within each ganglion cell, because the unstimulated activity of two neighboring ganglion cells can be remarkably correlated.
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Phototransduction by Retinal Ganglion Cells That Set the Circadian Clock
Science, 2002D. Berson, Felice A. Dunn, M. Takao
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Retinal Ganglion Cell Shrinkage in Glaucoma
Journal of Glaucoma, 2002There has been some debate concerning the selective loss of retinal ganglion cells belonging to the magnocellular pathway in early glaucoma. Although histologic studies of retinal ganglion cells in experimental and human glaucoma have suggested selective loss of the larger cells and, by implication, selective damage to the magnocellular pathway, this ...
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Rodent Retinal Ganglion Cell Cultures
2012Central neurons lose the ability for axonal regrowth during development and typically do not regenerate their axons following axotomy once they become mature unless given a growth-permissive environment, for example, a peripheral nerve graft. Retinal ganglion cells (RGCs) of the optic nerve represent a highly useful cell model for the study of ...
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