Results 91 to 100 of about 63,897 (287)

Berberine alleviates cell pyroptosis in diabetic retinopathy by regulating AKT1, JUN, and STAT3

Ibrain, EarlyView.
Berberine alleviates diabetic retinopathy by reducing pyroptosis through AKT1/JUN/STAT3 regulation, as validated in rat models via network pharmacology, molecular docking, and experimental assays. Abstract Berberine (BBR) exerts an effective protection for diabetic retinopathy (DR), but the underlying key molecular mechanism remains unknown; this study
Na Li, Ji‐Lin Chen, Yi‐Jian Sun, Jia‐Fan Sun, Fatin Athirah Pauzi, Song‐Lin Zhu, Amy Yi Hsan Saik, Alan Han‐Kiat Ong   +7 more
wiley   +1 more source

Correlation of hemorrhage, axonal damage and blood-tissue barrier disruption in brain and retina of Malawian children with fatal cerebral malaria

Frontiers in Cellular and Infection Microbiology, 2015
Background: The retinal and brain histopathological findings in children who died from cerebral malaria (CM) have been recently described. Similar changes occur in both structures, but the findings have not been directly compared in the same patients.
Jesse eGreiner, Katerina eDorovini-Zis, Terrie E Taylor, Terrie E Taylor, Malcolm Edward Molyneux, Malcolm Edward Molyneux, Nicholas eBeare, Nicholas eBeare, Steve eKamiza, Valerie A White, Valerie A White   +10 more
doaj   +1 more source

Comparison of Intravitreal Bevacizumab Upload Followed by a Dexamethasone Implant versus Dexamethasone Implant Monotherapy for Retinal Vein Occlusion with Macular Edema [PDF]

, 2012
Purpose: To compare the efficacy and safety of three intravitreal bevacizumab upload injections followed by a dexamethasone implant versus dexamethasone implant monotherapy in eyes with macular edema due to retinal vein occlusion.
Haritoglou, Christos, Kampik, Anselm, Kook, Daniel, Mayer, Wolfgang J., Remy, Matthias, Reznicek, Lukas, Ulbig, Michael, Wolf, Armin   +7 more
core   +1 more source

Hypertensive retinopathy in pre‐eclampsia and its association with disease severity and neonatal outcomes: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Introduction Pre‐eclampsia (PE) involves systemic endothelial dysfunction and microvascular injury, yet routine obstetric care lacks noninvasive readouts of maternal microvascular health. We evaluated whether hypertensive retinopathy (HR) detected during pregnancy is associated with maternal disease severity and adverse neonatal outcomes ...
Gabriele Saccone, Francesco Matarazzo, Mariarosaria Motta, Marika Rovetto, Michele Rinaldi, Maurizio Guida, Ciro Costagliola   +6 more
wiley   +1 more source

Preoperative electrophysiological characterization of patients with primary macula-involving rhegmatogenous retinal detachment [PDF]

, 2018
Purpose: To determine 1) which components of retinal function are impaired after rhegmatogenous retinal detachment, 2) which outer retinal pathways (rod- or cone-driven) are more severely affected, and 3) whether there is concomitant inner retinal ...
Apte, Rajendra, Lin, Jonathan, Sein, Julia, Van Stavern, Gregory   +3 more
core   +3 more sources

A randomized controlled trial of home‐applied dual‐light photodynamic therapy during supportive periodontal care (HOPE‐CP study)

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis is a common, chronic inflammatory disease that relies heavily on effective daily oral hygiene for long‐term control. Light‐based therapies have demonstrated strong antibacterial potential; however, their effectiveness in regular home use remains unexplored.
Saila Pakarinen, Hannamari Välimaa, Anna M. Heikkinen, Marja Noponen, Heikki Alapulli, Riitta K. T. Saarela, Taina Tervahartiala, Ismo T. Räisänen, Timo Sorsa, Dimitra Sakellari, Tommi Pätilä   +10 more
wiley   +1 more source

Ocular decompression retinopathy after anterior chamber paracentesis - Case series and systematic review

Taiwan Journal of Ophthalmology
To elucidate the mechanisms underlying multilayered retinal hemorrhage following anterior chamber paracentesis and to provide a comprehensive overview of the clinical features, risk factors, and prognosis for this complication.
Sung-Ting Hsu, Yung-Jen Lai, Wei-Chun Chan, Fang-Yi Chiu   +3 more
doaj   +1 more source

A Novel Slit Lamp‐Based System for 3D Ultrasound of the Eye

Journal of Ultrasound in Medicine, EarlyView.
Objectives This study aims to develop and evaluate a novel slit‐lamp‐based system to acquire 3‐dimensional (3D) ultrasound volumes using conventional ultrasound probes. Methods A slit‐lamp adapter was 3D printed and connected with a linear actuator and graphical user interface (GUI) system to control movement and create volumes of 2‐dimensional scans ...
Claire E. Malley, Joseph P. Miller, Boyan Pan, Josiah K. To, Jack O. Thomas, Steven Y. Chang, Jason Dagoon, William C. Tang, Parsa Riazi Esfahani, Andrew W. Browne   +9 more
wiley   +1 more source

Vision loss following snakebite in a patient with controlled aplastic anemia

Journal of Venomous Animals and Toxins including Tropical Diseases, 2009
Viper venoms act mainly on blood and blood vessels. Reports of ophthalmic manifestations after snakebite include ptosis and ophthalmoplegia. In the current study, we describe a case that developed bilateral retinal and subretinal hemorrhage following ...
EY Kweon, DW Lee, M Ahn, TM Nork, NC Cho
doaj   +1 more source

Associations Between Initial Glycated Hemoglobin at Diabetes Diagnosis, Longitudinal Changes and Medication Effects, and the Severity and Progression of Sight‐Threatening Diabetic Retinopathy

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic retinopathy (DR) is a leading cause of vision impairment in patients diagnosed with Type 2 diabetes mellitus (T2DM). Awareness of risk factors is necessary to reduce or prevent harmful effects of DR such as irreversible vision loss, and to help ensure early treatment.
Yu‐Chi Sung, Yu‐Kuang Chen, Ching‐An Chen, Pei‐Kang Liu, Kai‐Chun Cheng, Wei‐Shan Chang, Chia‐Li Tseng, Hui‐Min Hsieh, Shwu‐Jiuan Sheu   +8 more
wiley   +1 more source