Results 41 to 50 of about 2,026,781 (305)
Scientific Reports, 2017 Age-related macular degeneration (AMD), a leading contributor of vision loss, currently lacks comprehensive treatment. While AMD histopathology involves retinal pigment epithelium (RPE) injury associated with immune cell infiltration, the nature of ...
Wenxin Ma +5 more
doaj +1 more source
Frontiers in Neuroanatomy, 2021 Purpose: To present a methodology for quantification of the canine retinal vasculature imaged by optical coherence tomography angiography (OCTA) and validate this approach by comparison with fluorescein angiography (FA) and confocal imaging of retinal ...
Ana Ripolles-Garcia +6 more
doaj +1 more source
Scientific ReportsThe short-term conversion rate of a non-exudative macular neovascularization (ne-MNV) to an exudative stage in age-related macular degeneration (AMD) was evaluated in a single-center, retrospective case control study and associated imaging ...
Anna-Maria Haas +6 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Classification of acute retinal pigmentepithelitis
Journal of Ophthalmic Inflammation and InfectionPurpose To present a pediatric case of acute retinal pigment epitheliitis (ARPE) and propose a classification based on imaging findings and prognosis. Methods A case report with literature review.
Daniel Ahmed-Balestra +3 more
doaj +1 more source
Wide-field angiography in retinal vein occlusions
International Journal of Retina and Vitreous, 2019 Background Retinal vein occlusion (RVO) is the second most common retinal vascular disease after diabetic retinopathy. It can result in significant visual loss from complications like macula edema, retinal and iris neovascularization, and vitreous ...
Colin S. Tan +2 more
doaj +1 more source
Microperimetry and Multimodal Retinal Imaging
, 2014 Microperimetry allows precise functional examination of the retina and optic nerve and is included in the current multimodal (or integrated) imaging approach to the retina, primarily for the evaluation of the macular area. Macular disorders are among the
MIDENA, EDOARDO
core +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source