Results 121 to 130 of about 37,318 (280)

Hydrogel‐based drug delivery systems for intracerebral hemorrhage with therapeutic advances and emerging roles of the bone–brain axis

open access: yesInterdisciplinary Medicine, EarlyView.
Hydrogel‐based drug delivery systems offer a promising approach for treating intracerebral hemorrhage (ICH) by overcoming blood‐brain barrier limitations, enabling precise, sustained release of neuroprotective and anti‐inflammatory agents. These systems enhance treatment efficacy, but challenges remain in biosafety, drug penetration, and scalability ...
Haojun Shi   +18 more
wiley   +1 more source

A Case Of Rapidly Progressive Carcinoma-Associated Retinopathy Secondary To Metastatic Neuroblastoma In The Adult

open access: yes, 2014
Carcinoma-Associated Retinopathy (CAR) is one of the least common causes of visual dysfunction in patients with neoplasms. Patients with CAR develop anti-retinal antibodies that cause concomitant loss of vision with rod and cone dysfunction.
Gerard L. Hershewe; Javier A. Rodriguez
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Neoplastic disorders of visual apparatus in clinical optometry: advances and management

open access: yes, 2022
Ocular neoplasms, both primary and metastatic, may present with visual disturbance or vision loss and often are asymptomatic. Clinical examination may demonstrate leukocoria, abnormal pupillary light reflex, or a mass lesion with or without retinal ...
Dania, A. V.
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From regulatory mechanisms to cutting‐edge applications: Research progress of ultrasound, electrical, magnetic, and optical stimulation in neural modulation

open access: yesJournal of Intelligent Medicine, EarlyView.
Abstract In recent years, the clinical treatment and symptom management of neurological disorders have faced significant challenges due to the high complexity of the nervous system's structure and function. Against this backdrop, physical stimulation techniques have emerged as a vital complementary approach to traditional pharmacological treatments and
Wanying Li, Liqun Chen
wiley   +1 more source

Comparative Evaluation of Four Stereotactic Radiosurgery Planning Approaches for Treatment of Posterior Choroidal Melanoma

open access: yesJournal of Medical Radiation Sciences, EarlyView.
This study evaluated four stereotactic radiosurgery planning approaches for posterior choroidal melanoma (CM). Analysis of thirteen CM cases resulted in a clinically meaningful reduction in dose to the brain for Brainlab Elements modulated arcs (BE) and Varian Eclipse HyperArc modulated arcs (HA) compared to Brainlab iPlan dynamic conformal arc therapy
Robert Nigro   +5 more
wiley   +1 more source

A Novel Slit Lamp‐Based System for 3D Ultrasound of the Eye

open access: yesJournal of Ultrasound in Medicine, EarlyView.
Objectives This study aims to develop and evaluate a novel slit‐lamp‐based system to acquire 3‐dimensional (3D) ultrasound volumes using conventional ultrasound probes. Methods A slit‐lamp adapter was 3D printed and connected with a linear actuator and graphical user interface (GUI) system to control movement and create volumes of 2‐dimensional scans ...
Claire E. Malley   +9 more
wiley   +1 more source

Beyond Skin and Eyes: The Medical and Social Burden of Oculocutaneous Albinism in Africa: A Narrative Review

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Oculocutaneous albinism (OCA) is a genetic disorder found worldwide, but its impact is particularly pronounced in the African continent. This results from both a higher prevalence and the persistent myths and superstitions surrounding the condition in many African communities.
Rebecca Donadoni   +3 more
wiley   +1 more source

Molecular Mechanism of the IRF1/NFE2L1‐DT/ALKBH5/Cx43 Axis in Radiation‐Induced Injury in Vascular Endothelial Cells Through Pyroptosis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Radiotherapy effectively eradicates tumor cells but can also trigger pyroptotic damage in vascular endothelial cells. This study investigates the role of interferon regulatory factor 1 (IRF1) in radiation‐induced endothelial injury, aiming to provide mechanistic insights for optimizing radiotherapy.
Chen Li   +4 more
wiley   +1 more source

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Fundus changes in AIDS

open access: yes, 1987
A IDS is a devastating disease that affects 28,000 people in the United States and has claimed over 16,000 lives. More than 270,000 persons are expected to contract the syndrome by 1991. Most AIDS patients are male homosexuals, intravenous drug users, of
Baumgartner, Anthony Lee
core  

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