Results 171 to 180 of about 614,157 (313)

Single‐Cell RNA‐Seq Reveals Aging‐Related Impairment of Microglial Efferocytosis Contributing to Apoptotic Cells Accumulation After Retinal Injury

Aging Cell, EarlyView.
Microglia engage with apoptotic cells via cell‐surface receptors, such as proto‐oncogene tyrosine‐protein kinase MER (MerTK) and Axl; these receptors interact with the bridging molecule growth arrest‐specific 6 (Gas6) on apoptotic cells. Young microglia demonstrate efficient efferocytosis of apoptotic cells, but this process is impaired in aged ...
Pan Liu, Qi Wang, Shuimiao Wang, Ying Liu, Qiqi Chen, Wanyun Qin, Xinna Liu, Xinqi Ye, Yexuan Jiao, Huiping Yuan, Zhengbo Shao   +10 more
wiley   +1 more source

Influence of tamoxifen on ocular morphology and function. [PDF]

Oncologist
Strzalkowski P, Strzalkowska A, von der Ahe M, Ozga AK, Mohrmann S, Guthoff R, Geerling G, Spaniol K.   +7 more
europepmc   +1 more source

DLK/JNK3 Upregulation Aggravates Hair Cell Senescence in Mice Cochleae via Excessive Autophagy

Aging Cell, EarlyView.
In normal physiological processes, autophagy acts as a protective factor against aging stress. With the stress increase, the DLK/JNK3 pathway is activated and autophagy is continuously upregulated. In our study, excessive autophagy leads to hair cell senescence, which reveals that excessive autophagy can play a harmful role in senescence under certain ...
Rui Ding, Weiyi Huang, Chenling Shen, Yi Pan, Yiming Zhong, Bing Kong, Yilin Shen, Mingliang Xiang, Bin Ye   +8 more
wiley   +1 more source

Immunodeficiency Diseases and Tumor Immunobiology [PDF]

, 1974
Abramoff, Peter A., Duquesnoy, Rene J.
core   +1 more source

Clinical Characteristics and Management of Ocular Metastases. [PDF]

Cancers (Basel)
Gerba-Górecka K, Romanowska-Dixon B, Karska-Basta I, Cieplińska-Kechner E, Nowak MS.   +4 more
europepmc   +1 more source

Semaglutide and non‐arteritic anterior ischaemic optic neuropathy: Review and interpretation of reported association

Acta Ophthalmologica, EarlyView.
Abstract This review covers a seminal study of the relation between exposure to the glucagon‐like peptide 1 (GLP‐1) agonist semaglutide and incident non‐arteritic anterior ischaemic optic neuropathy (NAION) in a neuro‐ophthalmology clinic setting, subsequent studies in unselected populations, a meta‐analysis of clinical trials and pathophysiology ...
Abdullah Amini, Steffen Hamann, Michael Larsen   +2 more
wiley   +1 more source

Retinal capillary hemangioma in a pthisical globe: Late sequelae in a case of Von Hippel-Lindau (VHL) disease presenting with endophthalmitis. [PDF]

Int J Surg Case Rep
Helmi HA, Alsaad R, Alkhiary H, Alkatan HM.   +3 more
europepmc   +1 more source

Visual outcome including visual field defects after treatment of paediatric optic pathway glioma: A nationwide cohort study

Acta Ophthalmologica, EarlyView.
Abstract Purpose To examine long‐term visual impairment and visual field examination (VF) after diverse treatments for paediatric optic pathway glioma (OPG), and to determine prognostic factors for long‐term severe visual impairment or blindness. Methods A nationwide retrospective cohort study (1995–2018) was performed on paediatric OPGs that received ...
C. A. M. Bennebroek, J. van Zwol, M. C. Montauban van Swijndregt, S. E. Loudon, A. L. W. Groot, N. J. C. Bauer, J. W. Pott, I. C. Notting, A. J. van Sorge, M. M. van Genderen, P. de Graaf, A. Y. N. Schouten‐van Meeteren, P. Saeed, G. L. Porro   +13 more
wiley   +1 more source

Cancer-Associated Retinopathy as the Sole Presenting Sign of Small Cell Lung Cancer: A Case Report. [PDF]

Cureus
Phung QH, McClelland C, Desai H, Messersmith L, Reinhardt L, Kratzke R.   +5 more
europepmc   +1 more source

Aqueous humour concentrations of HB‐EGF, EGF and VEGF‐A and axial length in humans

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate relationships between the intraocular concentrations of heparin‐binding epidermal growth factor (HB‐EGF), epidermal growth factor (EGF) and vascular endothelial growth factor A (VEGF‐A) in dependence on axial length in humans. Design Clinical interventional cohort study.
Wen‐Da Zhou, Li Dong, Yu‐Hang Yang, Yuan He, Xiao‐Zhen Wang, Han‐Qing Zhao, Rui‐Heng Zhang, Jost B. Jonas, Wen‐Bin Wei   +8 more
wiley   +1 more source