Results 211 to 220 of about 614,157 (313)

Genetic Association of Primary Angle‐Closure Glaucoma and Disease Progression

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To investigate single‐nucleotide polymorphisms (SNPs) reported in the largest up‐to‐date systematic review and meta‐analysis on primary angle‐closure disease (PACD), on their associations with primary angle‐closure glaucoma (PACG) and disease progression.
Yu Jing Liang, Anni Ling, Poemen P. Chan, Jason C. Yam, Chi Pui Pang, Clement C. Tham, Li Jia Chen   +6 more
wiley   +1 more source

A Closer Look: Familial Adenomatous Polyposis Suspected Through Ophthalmological Findings in an Adolescent. [PDF]

Cureus
Freitas JD, Ferreira MR, Mota D, Marante S, Matapa S.   +4 more
europepmc   +1 more source

Diagnostic Ability of Transverse Axial Images Obtained by Optical Coherence Tomography for Detecting Anterior Displacement of Peripapillary Tissues in Papilledema

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To evaluate the diagnostic ability of optical coherence tomography (OCT) images to detect posterior pole deformation and anterior displacement of the optic disc (ADOD) in papilledema before and after intracranial pressure reduction with medical treatment.
Gabriel Castilho S. Barbosa, Rodrigo S. Pegado, Fernanda N. Susanna, Kenzo Hokazono, Mário Luiz R. Monteiro, Leonardo Provetti Cunha   +5 more
wiley   +1 more source

CAVIN3 deficiency promotes vascular normalization in ocular neovascular disease via ERK/JAG1 signaling pathway. [PDF]

JCI Insight
Li W, Zhang Y, Zhu H, Su N, Sun R, Mao X, Yang Q, Yuan S.   +7 more
europepmc   +1 more source

Organoids in Haematologic Research: Advances and Future Directions

Cell Proliferation, EarlyView.
This review focuses on the advancements in organoid technology and its transformative role in haematological research, particularly in the modelling of haematopoietic tissues, blood diseases and drug development. It also offers an outlook on the future prospects of organoids in personalised medicine and the study of disease mechanisms.
Liangzheng Chang, Lu Li, Yuling Han, Hui Cheng, Liuliu Yang   +4 more
wiley   +1 more source

BELZUTIFAN FOR TREATMENT OF GIANT RETINAL HEMANGIOBLASTOMA WITH EXTRASCLERAL EXTENSION ASSOCIATED WITH VON HIPPEL-LINDAU SYNDROME. [PDF]

Retin Cases Brief Rep
Cotton CC, Chandrabhatla AS, Andrews PH, Purrow BW, Shildkrot YE.   +4 more
europepmc   +1 more source

Tetrahedral Framework Nucleic Acid‐Based Delivery of DJ‐1‐saRNA Prevent Retinal Ischaemia–Reperfusion Injury via Inhibiting Ferroptosis

Cell Proliferation, EarlyView.
Illustration of the preparation of tFNAs‐DJ‐1 saRNAs complex and its inhibitory effects on ferroptosis in R28 and retina. ABSTRACT Retinal ischaemia/reperfusion injury (RI/RI) is the primary pathophysiological mechanism underlying retinal ischaemic diseases, potentially resulting in significant and irreversible visual impairment.
Xianggui Zhang, Zhende Deng, Xiaoxiao Xu, Jingyi Zhu, Zhen Huang, Ya Ye, Jingying Liu, Delun Luo, Jinnan Liu, Ming Yan, Yanping Song   +10 more
wiley   +1 more source

Target Screening and Single Cell Analysis of Diabetic Retinopathy and Hepatocarcinoma. [PDF]

J Cell Mol Med
Shao Y, Duan B, Li H, Li X, Peng S, Zheng H, You Z.   +6 more
europepmc   +1 more source

Mitochondrial Mutation Leads to Cardiomyocyte Hypertrophy by Disruption of Mitochondria‐Associated ER Membrane

Cell Proliferation, EarlyView.
Cardiomyocytes with high m.3243A>G burden exhibited hypertrophic phenotype. Mitochondria dysfunction occurred and tended to become round in cardiomyocytes with high m.3243A>G burden. Mitochondria‐associated ER membrane (MAM) was disrupted in cardiomyocytes with high m.3243A>G burden.
Miao Yu, Min Song, Manna Zhang, Shuangshuang Chen, Baoqiang Ni, Xuechun Li, Wei Lei, Zhenya Shen, Yong Fan, Jianyi Zhang, Shijun Hu   +10 more
wiley   +1 more source

"Incidentally" discovered Von Hippel Lindau disease: an emerging clinical phenotype. [PDF]

Oncologist
Trinh MN, Bear L, Nahed BV, Iliopoulos O.   +3 more
europepmc   +1 more source