Results 231 to 240 of about 614,157 (313)

Limbal cystotomy by fine needle aspiration of a translucent iris cyst in a horse

open access: yesEquine Veterinary Education, EarlyView.
Summary A 4‐year‐old Cremello crossbred mare was referred to the Equine Veterinary Teaching Hospital of Utrecht University for a translucent iris cyst from the dorsal pupillary margin corpora nigra in the right eye. Although noninvasive diode laser treatment is the preferred method of pigmented cyst ablation, two attempts did not result in disruption ...
A. L. Hendrikx   +5 more
wiley   +1 more source

d‐amino acids: new functional insights

open access: yesThe FEBS Journal, EarlyView.
This review explores recent advances in understanding d‐amino acids (d‐AAs) and their pivotal roles across organisms, from plants to humans. d‐AAs have been implicated in key physiological processes, including cancer, inflammation, immune regulation, kidney disease, diabetes, and nervous system function.
Loredano Pollegioni   +5 more
wiley   +1 more source

Y12C mutation disrupts IMPDH cytoophidia and alters cancer metabolism

open access: yesThe FEBS Journal, EarlyView.
IMPDH, the rate‐limiting enzyme for de novo GTP synthesis, can form polymers and cytoophidia to enhance activity by reducing GTP inhibition. In this study, a Y12C mutation in IMPDH2 was introduced via ABEmax base‐editing in human cancer cell lines to disrupt IMPDH polymerisation.
Chia‐Chun Chang   +7 more
wiley   +1 more source

Cadherin‐6 controls neuronal migration during mouse neocortical development via an integrin‐mediated pathway

open access: yesThe FEBS Journal, EarlyView.
Neuronal migration plays essential roles in the establishment of mammalian brains, and its impairment causes severe developmental abnormalities and behavioral and cognitive deficits. Here, we report that cadherin‐6 (CDH6), an unusual cadherin molecule containing an RGD integrin‐binding motif in the first extracellular domain, controls the motility of ...
Yuki Hirota   +7 more
wiley   +1 more source

Associations of serum carotenoids with cardiovascular disease mortality among patients with metabolic dysfunction‐associated steatotic liver disease

open access: yesHepatology Research, EarlyView.
In metabolic dysfunction‐associated steatotic liver disease/metabolic dysfunction‐associated steatohepatitis patients aged <60 years, high serum β‐cryptoxanthin concentrations were inversely associated with CVD mortality. Abstract Aim High cardiovascular disease (CVD) mortality occurred among metabolic dysfunction‐associated steatotic liver disease ...
Qian‐Qian Wang   +5 more
wiley   +1 more source

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