Results 21 to 30 of about 654,251 (322)

Retinal vasoproliferative tumor regression after intravitreal aflibercept

Taiwan Journal of Ophthalmology, 2023
Retinal vasoproliferative tumors (RVPTs) are rare benign retinal lesions typically located in the inferotemporal peripheral retina. Several treatment options exist for the management of RVPTs, but no consensus has been proposed.
Ting-Wen Chu, Shawn H Tsai, Lee-Jen Chen
doaj   +1 more source

Busulfan Treatment for Myeloproliferative Disease may Reduce Injection Burden in Vascular Endothelial Growth Factor-Driven Retinopathy

American Journal of Ophthalmology Case Reports, 2022
Purpose: Myeloproliferative neoplasms (MPNs) have been associated with increased systemic levels of vascular endothelial growth factor (VEGF). This study investigated an association between systemic busulfan for treatment of MPN and the requirement for ...
Lauren A. Dalvin, Timothy W. Olsen, Sophie J. Bakri, Kristen McCullough, Ayalew Tefferi, Aref Al-Kali   +5 more
doaj   +1 more source

Case report: Obstructive azoospermia as the first presentation of Von Hippel-Lindau disease

Frontiers in Oncology, 2023
We report the case of a 38-year-old man whose diagnostic workup for primary infertility led to the discovery of obstructive azoospermia due to bilateral papillary cystadenoma of the epididymis (PCE). Given the rarity of this finding and because PCE could
Raffaele Scafa, Maurizio Merico, Alfonso Massimiliano Ferrara, Sara Watutantrige Fernando, Pava Srsen, Francesca Schiavi, Stefania Zovato, Alberto Ferlin, Alberto Ferlin   +8 more
doaj   +1 more source

Retinal drusen in patients with chronic myeloproliferative blood cancers are associated with an increased proportion of senescent T cells and signs of an aging immune system

Aging, 2021
The cause of age-related macular degeneration (AMD) is unknown, but evidence indicates that both innate and adaptive immunity play a role in the pathogenesis. Our recent work has investigated AMD in patients with myeloproliferative neoplasms (MPNs) since
Charlotte Liisborg, V. Skov, L. Kjær, H. Hasselbalch, T. Sørensen   +4 more
semanticscholar   +1 more source

Multimodal imaging of a sporadic retinal astrocytic hamartoma simulating retinoblastoma in a newborn

GMS Ophthalmology Cases, 2022
Objective: To report a sporadic astrocytic hamartoma simulating retinoblastoma in a newborn.Methods: Clinical data was reviewed retrospectively.Results: A 3-month-old baby with a history of perinatal asphyxia was referred to our ocular oncology clinic ...
Batu Oto, Bilge, Yilmaz Çebi, Aslihan, Kiliçarslan, Oguzhan, Sarici, Ahmet Murat   +3 more
doaj   +1 more source

Identification of autoantibodies against TRPM1 in patients with paraneoplastic retinopathy associated with ON bipolar cell dysfunction. [PDF]

PLoS ONE, 2011
Paraneoplastic retinopathy (PR), including cancer-associated retinopathy (CAR) and melanoma-associated retinopathy (MAR), is a progressive retinal disease caused by antibodies generated against neoplasms not associated with the eye.
Mineo Kondo, Rikako Sanuki, Shinji Ueno, Yuji Nishizawa, Naozumi Hashimoto, Hiroshi Ohguro, Shuichi Yamamoto, Shigeki Machida, Hiroko Terasaki, Grazyna Adamus, Takahisa Furukawa   +10 more
doaj   +1 more source

CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis [PDF]

, 2016
Retinoblastoma is a pediatric eye tumor in which bi-allelic inactivation of the Retinoblastoma 1 (RB1) gene is the initiating genetic lesion. Although recently curative rates of retinoblastoma have increased, there are at this time no molecular targeted ...
Boel, Annekatrien, Colpaert, Robin, Creytens, David, Deforce, Dieter, Dimitrakopoulou, Dionysia, Haustraete, Jurgen, L, J, Lepez, Trees, Naert, Thomas, Steyaert, Wouter, Van Nieuwenhuysen, Tom, Vleminckx, Kris, Willaert, Andy   +12 more
core   +2 more sources

Radiation retinopathy in patients treated for sinus and epipharingeal malignancies [PDF]

Vojnosanitetski Pregled, 2005
Background. Radiation retinopathy is vasculopathy induced by ionising radiation delivered by either brachytherapy or teletherapy for ocular and nonocular malignancies.
Kosanović-Jaković Natalija, Risimić Dijana, Petrović Lidija, Milenković Svetislav   +3 more
doaj   +1 more source

TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis [PDF]

, 2015
Truncating mutations in the tumor suppressor gene adenomatous polyposis coli (APC) are the initiating step in the vast majority of sporadic colorectal cancers, and they underlie familial adenomatous polyposis (FAP) syndromes.
Creytens, David, Geurs, Sarah, Naert, Thomas, Sanders, Ellen, Tran Thi, Hong, Van Imschoot, Griet, Van Nieuwenhuysen, Tom, Van Roy, Frans, Vleminckx, Kris   +8 more
core   +3 more sources

Tumors in von Hippel–Lindau Syndrome: From Head to Toe—Comprehensive State-of-the-Art Review [PDF]

, 2018
Von Hippel–Lindau syndrome (VHL) is an autosomal-dominant hereditary tumor disease that arises owing to germline mutations in the VHL gene, located on the short arm of chromosome 3.
Bhalla, Sanjeev, Ganeshan, Dhakshinamoorthy, Lubner, Meghan G., Menias, Christine O., Pickhardt, Perry J., Ramalingam, Preetha, Sandrasegaran, Kumaresan   +6 more
core   +1 more source