Profound Re-Organization of Cell Surface Proteome in Equine Retinal Pigment Epithelial Cells in Response to In Vitro Culturing [PDF]
The purpose of this study was to characterize the cell surface proteome of native compared to cultured equine retinal pigment epithelium (RPE) cells. The RPE plays an essential role in visual function and represents the outer blood-retinal barrier.
Kerstin N. Euler +25 more
core +1 more source
Biological effects of cigarette smoke in cultured human retinal pigment epithelial cells. [PDF]
The goal of the present study was to determine whether treatment with cigarette smoke extract (CSE) induces cell loss, cellular senescence, and extracellular matrix (ECM) synthesis in primary human retinal pigment epithelial (RPE) cells. Primary cultured
Johannes Burger +8 more
core +2 more sources
Long-term visual and microperimetry outcomes following autologous retinal pigment epithelium choroid graft for neovascular age-related macular degeneration [PDF]
To describe the 2- to 4-year visual and microperimetry outcomes of autologous retinal pigment epithelium (RPE)-choroid graft in patients with neovascular age-related macular degeneration (AMD).In this retrospective cohort study, 12 patients with ...
Coffey, PJ +9 more
core +1 more source
Retinal Pigment Epithelial Tear following Intravitreal Injection of Bevacizumab (Avastin)
Purpose To report one case of retinal pigment epithelium tear following intravitreal bevacizumab injection for neovascular age-related macular degeneration.
D. Ghiglione, G. Calabria, M. Nicolò
core +3 more sources
MFGE8 does not influence chorio-retinal homeostasis or choroidal neovascularization in vivo [PDF]
Purpose: Milk fat globule-epidermal growth factor-factor VIII (MFGE8) is necessary for diurnal outer segment phagocytosis and promotes VEGF-dependent neovascularization.
David-Alexandre Tregouet (4350982) +74 more
core +1 more source
Early stages of retinal development depend on Sec13 function [PDF]
ER-to-Golgi transport of proteins destined for the extracellular space or intracellular compartments depends on the COPII vesicle coat and is constitutive in all translationally active cells.
Feng, Yi +7 more
core +1 more source
The ocular albinism type 1 protein, an intracellular G protein-coupled receptor, regulates melanosome transport in pigment cells [PDF]
The protein product of the ocular albinism type 1 gene, named OA1, is a pigment cell-specific G protein-coupled receptor exclusively localized to intracellular organelles, namely lysosomes and melanosomes.
Bennett, DC +51 more
core +1 more source
Spontaneous Large Serous Retinal Pigment Epithelial Tear [PDF]
Purpose: To report cases of spontaneous retinal pigment epithelial (RPE) tear complicating serous pigment epithelial detachment (PED). Methods: The records of 3 Asian patients with spontaneous giant RPE tear were reviewed retrospectively by including ...
Nimitr Ittipunkul +5 more
core +1 more source
m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang +18 more
wiley +1 more source
Purpose: To evaluate the choroidal thickness with spectral domain optical coherence tomography in subjects with retinal pigment epithelial (RPE) tear compared with the choroidal thickness of their fellow eye.Methods: For this cross-sectional ...
Regatieri, Caio Vinicius Saito [UNIFESP] +4 more
core +1 more source

