Results 91 to 100 of about 261,050 (242)

Rest‐activity patterns across development in two mouse models of autism and epilepsy

Epilepsia Open, EarlyView.
Abstract Objective Sleep disturbances are common in individuals with autism spectrum disorder (ASD) and epilepsy and are increasingly recognized as comorbidities that affect disease severity and quality of life. This study investigated rest‐activity patterns across development in two genetic mouse models relevant to ASD and epilepsy: synapsin 2 (Syn2 ...
Ipsa Dash, Filip Fredlund, Jenny Wickham, My Andersson, Christine T. Ekdahl   +4 more
wiley   +1 more source

Retinal pigment epithelium tear after intravitreal aflibercept injection

Clinical Ophthalmology, 2013
Masaaki Saito, Mariko Kano, Kanako Itagaki, Yasuharu Oguchi, Tetsuju Sekiryu Department of Ophthalmology, Fukushima Medical University School of Medicine, Fukushima, Japan Abstract: To report a case complicated with a retinal pigment epithelium (RPE ...
Saito M, Kano M, Itagaki K, Oguchi Y, Sekiryu T   +4 more
doaj  

Non-viral delivery and optimized optogenetic stimulation of retinal ganglion cells led to behavioral restoration of vision [PDF]

, 2012
Stimulation of retinal neurons using optogenetics via use of chanelrhodopsin-2 (ChR2) has opened up a new direction for restoration of vision for treatment of retinitis pigmentosa (RP).
Shivaranjani Shivalingaiah, Samarendra Mohanty, Mathew Ficinski, Ling Gu, Edward Wong   +4 more
core   +1 more source

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

Exploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi, Denzil L. Furtado, Francesca Alves, Rebecca M. Nisbet, Scott Ayton, Ashley I. Bush   +5 more
wiley   +1 more source

An improvement in visual acuity accompanied by the development of RPE tear: a case report

BMC Ophthalmology
Background Retinal pigment epithelium (RPE) tear is a well-known complication of RPE detachment and is typically associated with significant visual acuity decline.
Xinyu Liu, Shulin Liu, Zhiyan Xu, Youxin Chen   +3 more
doaj   +1 more source

Two Cases of Rhegmatogenous Retinal Detachment Associated with Asteroid Hyalosis

Case Reports in Ophthalmology, 2018
Background: To report two cases of rhegmatogenous retinal detachment (RRD) associated with asteroid hyalosis (AH). Case Presentation: Two patients presented with RRD originating from a flap tear.
Yoshitaka Okuda, Keigo Kakurai, Takaki Sato, Seita Morishita, Masanori Fukumoto, Ryohsuke Kohmoto, Mai Takagi, Takatoshi Kobayashi, Teruyo Kida, Tsunehiko Ikeda   +9 more
doaj   +1 more source

Interventions for prevention of giant retinal tear in the fellow eye

, 2008
Background: A giant retinal tear is a full-thickness retinal break that extends circumferentially around the retina for 90 degrees ormore in the presence of a posteriorly detached vitreous.
Ang, GS, Townend, J., Lois, N., Noemi Lois, Ghee Soon Ang, Townend, John, John Townend, Townend, J, Ang, G.S., Lois, N   +9 more
core   +1 more source

Early stages of retinal development depend on Sec13 function [PDF]

, 2013
ER-to-Golgi transport of proteins destined for the extracellular space or intracellular compartments depends on the COPII vesicle coat and is constitutive in all translationally active cells.
Feng, Yi, Schmidt, Katy, Stephens, David J, Yi Feng, Katy Schmidt, David J. Stephens, Florencia Cavodeassi, Cavodeassi, Florencia   +7 more
core   +1 more source

Meniscus‐guided organic semiconductor single crystals: From fluid dynamics to morphology control and multifunctional applications

FlexMat, EarlyView.
Centered on the multiscale meniscus, this review dissects mass transport in meniscus‐guided coating into parallel and lateral components. By analyzing the balance of multiple factors during crystallization, it establishes a clear morphology‐performance relationship.
Yumeng Wang, Shengnan Chen, Lutong Guo, Lujing Shao, Zhenhua Li, Hao Liu, Yanlin Song, Yali Qiao   +7 more
wiley   +1 more source

Giant Retinal Tear as a Complication of Attempted Removal of Intravitreal Lens Fragments During Cataract Surgery

, 1997
To report giant retinal tear and retinal detachment as a complication of attempted removal of intravitreal lens fragments at the time of cataract surgery and to evaluate the anatomic and visual acuity outcomes of pars plana vitrectomy and retinal ...
FLYNN, HARRY W, SMIDDY, WILLIAM E, AABERG, THOMAS M, CHANG, STANLEY, MIELER, WILLIAM F, RUBSAMEN, PATRICK E   +5 more
core   +1 more source