Results 81 to 90 of about 1,036,280 (229)

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Cell‐Based Micro/Nanorobots: From Living Carriers to Living Therapeutic Specialists

SmartBot, EarlyView.
Cell‐based micro/nanorobots integrate evolutionarily acquired biological intelligence with engineered capabilities, offering new opportunities for precision medicine in vivo. However, the complex physiological environments of different organs pose significant challenges to their clinical translation.
Junfeng Wu, Zhaoyu Zhang, Ke Xu, Enkuo Li, Yuting Cui, Yuting Zhou, Huanyu Zhou, Beipei Zhang, Shuai Jiang, Xiaodong Wang, Jialin Jiang, Lianqing Liu, Niandong Jiao   +12 more
wiley   +1 more source

Hypertensive Disorders of Pregnancy and the Long‐Term Risk of Maternal Retinal and Ophthalmic Disease: A Systematic Review and Meta‐Analysis

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Hypertensive disorders of pregnancy (HDP) are associated with increased long‐term risk of maternal cardio‐metabolic disease, but links with future retinal diseases remain unclear. Objective The objective of this study is to synthesise the published literature on HDP and subsequent retinal and other ophthalmic disease.
Peter Barrett, Cian Carey, Sinéad O'Riordan, Angela Ding Wu, Emma Wallace, Matilda Biba, Karolina Kublickiene, Fergus McCarthy, Ali Khashan   +8 more
wiley   +1 more source

Interventional oncology in children: Where are we now?

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel, Fernando Gómez Muñoz   +1 more
wiley   +1 more source

A case report of branch retinal artery occlusion in a teenager due to hyperhomocysteinaemia; the interplay of genetic and nutritional defects

BMC Ophthalmology, 2018
Background Retinal vascular occlusions are uncommon in young people and require more in-depth investigation into the cause. Studies have revealed that a high level of circulating homocysteine poses a risk for retinal vaso-occlusive events across a wide ...
Clare Shute
doaj   +1 more source

Ischaemic Optic Neuropathy After Cardiac Surgery: A Systematic Review and Meta‐Analysis of Incidence and Risk Factors

ANZ Journal of Surgery, EarlyView.
Across 11 observational studies comprising 6 471 577 patients, the pooled incidence of ischaemic optic neuropathy after cardiac surgery was approximately 1.5 cases per 10 000 procedures. Coronary artery disease, peripheral vascular disease and anaemia were associated with increased odds of ION, although these findings should be interpreted in the ...
Daud Mutahar, Ammar Zaka, Amitouj S. Sidhu, Shahi Goswami, Aditi Singh, Jordan Ng, Brandon Stretton, Joshua G. Kovoor, Aashray K. Gupta, Stephen Bacchi, Weng Onn Chan, Celia Chen   +11 more
wiley   +1 more source

Retinal Artery Occlusion Secondary to Buerger’s Disease (Thromboangiitis Obliterans)

Case Reports in Ophthalmological Medicine, 2017
Purpose. To report a case report of one patient suffering from retinal artery occlusion secondary to Buerger’s disease, in order to raise awareness to this etiology in the differential diagnosis of retinal artery occlusion. Methods.
Erdem Eris, Mehmet Emin Sucu, Irfan Perente, Zeynep Alkın, Abdullah Ozkaya, Hatice Nur Tarakcioglu   +5 more
doaj   +1 more source

The Difference Of Visual Acuity And Macular Thickness Post Bevacizumab Therapy In Secondary Macular Edema Retinal Vein Occlusion

Journal of Agromedicine and Medical Sciences (AMS), 2018
Retinal vein occlusion is the second most common cause of blindness in retinal vascular disease after diabetic retinopathy and may lead to complications of macular edema.
Citra Rahmadani, Nur Khoma Fatmawati, Rahmat Bakhtiar   +2 more
doaj   +1 more source

Exploring market dynamics of biological including biosimilar treatments for retinal diseases in Europe: An interrupted time‐series analysis

Acta Ophthalmologica, EarlyView.
Abstract Purpose To assess the impact of biosimilar ranibizumab and on‐patent faricimab market entry on pricing and utilization trends and describe national variation in off‐label bevacizumab use in Europe. Methods Interrupted time series analysis of quarterly sales data (Q1 2018–Q2 2024) in 11 European countries evaluated ranibizumab utilization and ...
Elif Car, Isabelle Huys, Steven Simoens, Arnold G. Vulto   +3 more
wiley   +1 more source

Junctional sensitivity and atrophy progression rate of geographic atrophy secondary to age‐related macular degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose To determine the relationship between the baseline junctional retinal sensitivity measured with microperimetry and the atrophy progression rate in eyes with geographic atrophy (GA) secondary to age‐related macular degeneration. Methods In this prospective cohort study, patients with GA were examined with fundus autofluorescence (FAF ...
Alexander Kai Thomsen, Jenni Martinez Villarruel Hinnerskov, Miranda Maung, Aubin Mutschler, SriniVas Sadda, Torben Lykke Sørensen   +5 more
wiley   +1 more source