Results 11 to 20 of about 54,597 (268)

ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver

Hepatology, EarlyView., 2022
Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid, Victor Olsavszky, Manuel Reinhart, Vanessa Weyer, Felix A. Trogisch, Carsten Sticht, Manuel Winkler, Sina W. Kürschner, Johannes Hoffmann, Roxana Ola, Theresa Staniczek, Joerg Heineke, Beate K. Straub, Jens Mittler, Kai Schledzewski, Peter ten Dijke, Karsten Richter, Steven Dooley, Cyrill Géraud, Sergij Goerdt, Philipp‐Sebastian Koch   +20 more
wiley   +1 more source

Central Retinal Vein Occlusion: Etiology, Clinical Presentation and Treatment

Journal of Education, Health and Sport
Introduction and Purpose: Retinal vein occlusion (RVO) occurs when the lumen of the retinal vein closes. Central retinal vein occlusion is the second most common retinal vascular disease.
Grzegorz Szcześniak, Aleksandra Kiełczewska, Anna Kiełczewska   +2 more
doaj   +1 more source

Dye-Free Porcine Model of Experimental Branch Retinal Vein Occlusion: A Suitable Approach for Retinal Proteomics

Journal of Ophthalmology, 2015
Branch retinal vein occlusion induces complex biological processes in the retina that are generated by a multitude of interacting proteins. These proteins and their posttranslational modifications can effectively be studied using modern proteomic ...
Lasse Jørgensen Cehofski, Anders Kruse, Benedict Kjærgaard, Allan Stensballe, Bent Honoré, Henrik Vorum   +5 more
doaj   +1 more source

association oF systemic Diseases witH retinal vein occlusive Disease

Journal of Nepal Medical Association, 2006
Retinal vein occlusion (RVO) is the second commonest vascular disease of the eye, second only to Diabetic Retinopathy. The association of the retinal vein occlusion with other systemic disease likes hypertension, diabetes mellitus and others has been ...
Rajesh Kishor Shrestha, J K Shrestha, S Koirala, D N Shah   +3 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Association of factor V Leiden mutation with retinal vein thrombosis in a set of Iraqi patients

Iraqi Journal of Hematology, 2016
Background: Retinal vein occlusion is the most common retinal vascular disorder after diabetic retinopathy with several ocular and systemic disorders associated with retinal veins thrombosis.
Rahem Mahdy Rahem, Rehab Abdul Sahb Al-Waeli   +1 more
doaj   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source

ROLE OF BEVACIZUMAB FOR PREVENTION OF NEOVASCULAR GLAUCOMA IN ACUTE RETINAL VEIN OCCLUSION [PDF]

Journal of University Medical & Dental College, 2018
: There is a possibility of developing neovascular glaucoma in ischemic type of retinal vein occlusion. Purpose of the study is to determine the role of anti VEGF agent bevacizumab for prevention of neovascular glaucoma in ischemic type of retinal vein ...
Bassam Mubarik , Adeen Akram
doaj   +1 more source

Case series of branch retinal vein occlusion secondary to rhegmatogenous retinal detachment and its surgical management

BMC Ophthalmology, 2023
Background To review cases of branch retinal vein occlusion (BRVO) secondary to rhegmatogenous retinal detachment (RRD) and its surgical management and presume their mechanism.
Youna Choi, Sung Jun Kim, Jae Jung Lee, Moosa Hasan Zaidi, Yong Un Shin, Ik Soo Byon, Ji Eun Lee, Sung Who Park   +7 more
doaj   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source