Results 91 to 100 of about 22,634 (197)

Dissecting the angiogenic mechanism of pachychoroid polypoidal choroidal vasculopathy

iMeta, Volume 5, Issue 5, October 2026.
A prognosis‐oriented classification system was established to distinguish Pachy PCV from Non‐pachy PCV using a large multicenter dataset. Comparative plasma multi‐omics profiling of Pachy PCV, Non‐pachy PCV, and normal controls revealed unique upregulation of the fluid shear stress and atherosclerosis (FSS‐AS) and HIF‐1 signaling pathways in Pachy PCV.
Xinyu Zhao, Tiantian Cheng, Wenfei Zhang, Xingwang Gu, Qing Zhao, Yaning Chen, Lihui Meng, Jiaqi Zhang, Bintao Qiu, Lili Li, Shiyu Cheng, Zicheng Wang, Chuting Wang, Yuelin Wang, Zuyi Yang, Zhengming Shi, Ye Guo, Shengzhi Liu, Youxin Chen   +18 more
wiley   +1 more source

Reply to “Aflibercept 8 mg: From Ocular Clearance to Pharmacodynamic Duration”

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 11, November 2026.
Sébastien Bihorel, Joannellyn Chiu, Jason Chittenden, Thomas Eissing, Kenneth C. Turner, Joachim Höchel, Zhongqing Will He, John D. Davis, Lutz O. Harnisch   +8 more
wiley   +1 more source

Iron and Other Metal Ions in Human Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley   +1 more source

Fumarate and Its Esters: Physiology, Pathology, Molecular Mechanisms, Diseases, and Therapy

MedComm, Volume 7, Issue 10, October 2026.
Fumarate is an endogenous immunometabolite that regulates metabolism, redox homeostasis, and inflammation. Although fumaric acid esters (FAEs) share several molecular targets with fumarate, their distinct physicochemical properties confer unique biological activities and therapeutic applications.
Peng Zhu, Mengling You, Yi Zeng, Jinglin Zhang, Si Chen, Rong Rong, Xiaobo Xia   +6 more
wiley   +1 more source

Pars plana vitrectomy and internal limiting membrane peeling for macular edema secondary to retinal vein occlusion

Clinical Ophthalmology, 2011
Nader Baharivand, Amirhossein Hariri, Alireza Javadzadeh, Ebadollah Heidari, Karim SadegiNikookari Eye Hospital, Tabriz University of Medical Sciences, Tabriz, IranPurpose: To evaluate the effects of vitrectomy and internal limiting membrane peeling for ...
Bahariv, N, Hariri A, Javadzadeh A, Heidari E, Sadegi K   +3 more
doaj  

Retinal vascular occlusions during COVID-19: an epidemiological survey

Frontiers in Ophthalmology
PurposeTo evaluate whether the COVID-19 pandemic was associated with changes in the incidence of retinal vascular occlusions. MethodsWe performed a retrospective cohort study at the Jules-Gonin Eye Hospital (Lausanne).
Andrea Montesel, Yan Guex-Crosier, Chiara M. Eandi, Chiara M. Eandi   +3 more
doaj   +1 more source

Insights into the modulation of age‐related macular degeneration: Molecular and systems‐level perspectives

Acta Ophthalmologica, Volume 104, Issue S293, Page S4-S35, October 2026.
ENGLISH SUMMARY In developed countries, age‐related macular degeneration (AMD) is the leading cause of visual impairment in the aging population. Understanding of its pathogenesis is limited and the number of patients is predicted to continue rising. AMD is classified into two main forms: dry and neovascular AMD (dAMD and nAMD, respectively).
Hanna Heloterä
wiley   +1 more source

Suppression of Retinal Neovascularisation by Tetrahedral Framework Nucleic Acids‐Resveratrol Via Dual Anti‐Angiogenesis and Anti‐Inflammation

Cell Proliferation, Volume 59, Issue 10, October 2026.
Resveratrol‐loaded tetrahedral framework nucleic acids (tFNAs‐RSV) enable concurrent anti‐angiogenic and anti‐inflammatory therapy, enhancing ocular delivery and bioactivity. In hypoxia‐induced retinal neovascularisation, tFNAs‐RSV reduce neovascular lesions, vascular leakage and inflammatory infiltration by suppressing HIF‐1, p38 MAPK and NF‐κB p65 ...
Yili Jin, Tao Cai, Junyang Huang, Li Chen, Yi Lin, Jingying Liu, You Wang, Xiaoyan Ding   +7 more
wiley   +1 more source

The progress of assessment methods and treatments of neovascular glaucoma secondary to central retinal vein occlusion

Frontiers in Medicine
Neovascular glaucoma is a condition that results from central retinal vein occlusion and often leads to blindness. Accurate evaluation and appropriate treatment are crucial for patients.
Sheng Qu, Ying Zou, Li Yang, Hong Wu
doaj   +1 more source

Bilateral Retinal Vein Occlusion and Rubeosis Irides: Lessons To Learn

Acta Medica Iranica, 2013
Uncontrolled hypertension is well- known to give rise to systemic complications involving multiple central organs. Artherosclerosis leads to damage of the retinal vessels wall, contributing to venous stasis, thrombosis and finally, occlusion.
Umi Kalthum Md Noh, Amin Ahem, Mushawiahti Mustapha   +2 more
doaj