Human Cyclophilins—An Emerging Class of Drug Targets
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
wiley +1 more source
Persistent reduction of retinal microvascular vessel density in patients with moderate and severe COVID-19 disease [PDF]
Sandra Banderas García +8 more
openalex +1 more source
Targeted conservation measures are contingent on robust knowledge of spatio‐temporal animal distribution in areas of interest. We explore unmanned aerial vehicle (UAV) transect monitoring as a novel method for standardized digital aerial surveys of marine megafauna by investigating the fine‐resolution spatio‐temporal distribution of harbour porpoises ...
Dinah Hartmann +2 more
wiley +1 more source
Retinoblastoma tumour cells in central retinal vessels. [PDF]
Mohan S, Subramanian K, Khetan V.
europepmc +1 more source
Retinal Vessel Segmentation based on Hunger Games Search and Reptile Search Algorithms
Mehmet Bahadır Çetinkaya, Hakan Duran
openalex +1 more source
This study shows that human iPSC‐derived endothelial cells acquire a functional blood–brain barrier phenotype when co‐cultured with brain pericytes and stimulated with CHIR‐99021, a Wnt/β‐catenin activator. This model recapitulates key barrier properties, inflammatory responses, and transcriptomic features of the native human BBB, offering new ...
Henrique Nogueira Pinto +12 more
wiley +1 more source
Clinical Research of Lupus Retinopathy: Quantitative Analysis of Retinal Vessels by Optical Coherence Tomography Angiography in Patients with Systemic Lupus Erythematosus. [PDF]
Wang X +5 more
europepmc +1 more source
Structure Function Relationships of Vessel Density and Retinal Nerve Fiber Layer Thickness in Early Glaucomatous Eyes With High Myopia [PDF]
Kaho Akiyama +10 more
openalex +1 more source
Retinal imaging in pre‐eclamptic pregnancy: systematic review
ABSTRACT Objective To explore potential changes in retinal structures in pregnant women with pre‐eclampsia (PE). Methods This was a systematic review of the literature on retinal assessment in pregnancies complicated by PE. PubMed, EMBASE via Ovid, The Cochrane Library and Scopus databases were searched in July 2025 using an a‐priori‐designed protocol ...
D. Kitmiridou +3 more
wiley +1 more source
Assessment of the Retinal Vessels in Keratoconus: An OCT Angiography Study. [PDF]
Wylęgała A +3 more
europepmc +1 more source

