Results 131 to 140 of about 143,576 (340)

Human Cyclophilins—An Emerging Class of Drug Targets

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova   +3 more
wiley   +1 more source

Persistent reduction of retinal microvascular vessel density in patients with moderate and severe COVID-19 disease [PDF]

open access: gold, 2022
Sandra Banderas García   +8 more
openalex   +1 more source

Programmed unmanned aerial vehicles show great potential for monitoring marine megafauna in specific areas of interest

open access: yesRemote Sensing in Ecology and Conservation, EarlyView.
Targeted conservation measures are contingent on robust knowledge of spatio‐temporal animal distribution in areas of interest. We explore unmanned aerial vehicle (UAV) transect monitoring as a novel method for standardized digital aerial surveys of marine megafauna by investigating the fine‐resolution spatio‐temporal distribution of harbour porpoises ...
Dinah Hartmann   +2 more
wiley   +1 more source

Retinoblastoma tumour cells in central retinal vessels. [PDF]

open access: yesIndian J Ophthalmol, 2022
Mohan S, Subramanian K, Khetan V.
europepmc   +1 more source

Brain Pericytes and Wnt/β‐Catenin Signaling Induce Functional Blood–Brain Barrier Phenotype in Human iPSC‐Derived Model

open access: yesSmall Methods, EarlyView.
This study shows that human iPSC‐derived endothelial cells acquire a functional blood–brain barrier phenotype when co‐cultured with brain pericytes and stimulated with CHIR‐99021, a Wnt/β‐catenin activator. This model recapitulates key barrier properties, inflammatory responses, and transcriptomic features of the native human BBB, offering new ...
Henrique Nogueira Pinto   +12 more
wiley   +1 more source

Structure Function Relationships of Vessel Density and Retinal Nerve Fiber Layer Thickness in Early Glaucomatous Eyes With High Myopia [PDF]

open access: gold, 2023
Kaho Akiyama   +10 more
openalex   +1 more source

Retinal imaging in pre‐eclamptic pregnancy: systematic review

open access: yesUltrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To explore potential changes in retinal structures in pregnant women with pre‐eclampsia (PE). Methods This was a systematic review of the literature on retinal assessment in pregnancies complicated by PE. PubMed, EMBASE via Ovid, The Cochrane Library and Scopus databases were searched in July 2025 using an a‐priori‐designed protocol ...
D. Kitmiridou   +3 more
wiley   +1 more source

Assessment of the Retinal Vessels in Keratoconus: An OCT Angiography Study. [PDF]

open access: yesJ Clin Med, 2022
Wylęgała A   +3 more
europepmc   +1 more source

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