Visualization of Endothelial Actin Cytoskeleton in the Mouse Retina [PDF]
Angiogenesis requires coordinated changes in cell shape of endothelial cells (ECs), orchestrated by the actin cytoskeleton. The mechanisms that regulate this rearrangement in vivo are poorly understood - largely because of the difficulty to visualize ...
Alessia Fraccaroli +10 more
core +5 more sources
VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia [PDF]
Vascular endothelial growth factor (VEGF-A) is a major regulator of blood vessel formation and function. it controls several processes in endothelial cells, such as proliferation, survival, and migration, but it is not known how these are coordinately ...
Abramsson, A +10 more
core +2 more sources
Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid +20 more
wiley +1 more source
Age and diabetes related changes of the retinal capillaries: an ultrastructural and immunohistochemical study [PDF]
Normal human aging and diabetes are associated with a gradual decrease of cerebral flow in the brain with changes in vascular architecture. Thickening of the capillary basement membrane and microvascular fibrosis are evident in the central nervous system
ARTICO, Marco +10 more
core +1 more source
Micro-Vessel Image Segmentation Based on the AD-UNet Model
Retinal vessel segmentation plays a vital role in computer-aided diagnosis and treatment of retinal diseases. Considering the low contrast between retinal vessels and the background image, complex structural information as well as blurred boundaries ...
Zhongming Luo +5 more
doaj +1 more source
Retinal blood vessels segmentation using classical edge detection filters and the neural network
Retinal blood vessels analysis is of interest for medical screening, especially in the diagnosis of diabetic retinopathy. In this paper, we propose a new method for the segmentation of blood vessels in retinal photographs.
Beaudelaire Saha Tchinda +4 more
doaj +1 more source
Trainable COSFIRE filters for vessel delineation with application to retinal images [PDF]
Retinal imaging provides a non-invasive opportunity for the diagnosis of several medical pathologies. The automatic segmentation of the vessel tree is an important pre-processing step which facilitates subsequent automatic processes that contribute to ...
Azzopardi, George, Petkov, Nicolai
core +1 more source
RETINAL VESSEL ANALYSIS - NEW POSSIBILITIES [PDF]
Retinal Vessel Analysis is a new technique to assess behavior of large retinal vessels based on diameter measurements. The Retinal Vessel Analyzer (RVA) measures continuously on-line obtaining data in relation to time and local position. Possible analysis tools include (a) Time Course Analysis of physiological, pathological, or therapy induced changes;
W, Vilser, E, Nagel, I, Lanzl
openaire +2 more sources
Retinal Health Investigation by Segmentation of Major and Minor Blood Vessels in Fundus Images for Diabetes Patients [PDF]
Introduction: The Major and Minor blood vessel and the optic disc are the important factors for finding the presence of retinal disease like diabetic retinopathy.
S Poonguzhali, Rekha Chakravarthi
doaj +1 more source
Glycocalyx Degradation in Retinal and Choroidal Capillary Endothelium in Rats with Diabetes and Hypertension [PDF]
Endothelial glycocalyx (GCX) has been reported as a protective factor for vascular endothelial cells (VEC) in diabetes and hypertension. However, the involvement of GCX impairment in ocular vasculopathy remains unclear.
Kumase, Fumiaki +5 more
core +1 more source

