Results 31 to 40 of about 83,492 (257)

ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver

Hepatology, EarlyView., 2022
Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid, Victor Olsavszky, Manuel Reinhart, Vanessa Weyer, Felix A. Trogisch, Carsten Sticht, Manuel Winkler, Sina W. Kürschner, Johannes Hoffmann, Roxana Ola, Theresa Staniczek, Joerg Heineke, Beate K. Straub, Jens Mittler, Kai Schledzewski, Peter ten Dijke, Karsten Richter, Steven Dooley, Cyrill Géraud, Sergij Goerdt, Philipp‐Sebastian Koch   +20 more
wiley   +1 more source

Discordance in Retinal and Choroidal Vascular Densities in Patients with Type 2 Diabetes Mellitus on Optical Coherence Tomography Angiography

Journal of Ophthalmology, 2021
Purpose. In the present study, the retinal and choroidal vascular densities (VDs) in type 2 diabetes mellitus (DM) patients were analyzed using optical coherence tomography angiography (OCTA). Methods.
Ho Ra, Nam Yeo Kang, Jiyun Song, Junhyuck Lee, Inkee Kim, Jiwon Baek   +5 more
doaj   +1 more source

Retinal Vessel Segmentation Algorithm Based on Residual Convolution Neural Network

Frontiers in Bioengineering and Biotechnology, 2021
Retinal vessels are the only deep micro vessels that can be observed in human body, the accurate identification of which has great significance on the diagnosis of hypertension, diabetes and other diseases.
Shuang Xu, Shuang Xu, Zhiqiang Chen, Zhiqiang Chen, Weiyi Cao, Feng Zhang, Feng Zhang, Bo Tao, Bo Tao   +8 more
doaj   +1 more source

Comparative Analysis of Vessel Segmentation Techniques in Retinal Images

IEEE Access, 2019
The blood vessels are the primary anatomical structure that can be visible in retinal images. The segmentation of retinal blood vessels has been accepted worldwide for the diagnosis of both cardiovascular (CVD) and retinal diseases.
Azhar Imran, Jianqiang Li, Yan Pei, Ji-Jiang Yang, Qing Wang   +4 more
doaj   +1 more source

Choroidal shift in myopic eyes in the 10-year follow-up Beijing eye study

Scientific Reports, 2021
The aim of the study was to assess longitudinal changes in the spatial relationship of the choroidal vasculature to retinal vasculature in myopic eyes.
Jost B. Jonas, Yan Ni Yan, Qi Zhang, Rahul A. Jonas, Ya Xing Wang   +4 more
doaj   +1 more source

WHAT IS THE BEST METHOD TO EVALUATE RETINAL MICROCIRCULATION?

Artery Research, 2015
The microvasculature of retinal ganglion cell layer, which is the part of central nervous system, can be investigated non-invasively in human. For clinical routine the fluorescence angiography is used to test patency and leak of retinal or choroid ...
Joanna Harazny
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

High‐Throughput Digital Decoding of Vascular Heterogeneity in Patient‐Specific Tumor Microenvironments

Advanced Healthcare Materials, EarlyView.
ABSTRACT Quantitative characterization of vascular heterogeneity in complex microphysiological systems (MPS), particularly within patient‐derived tumor microenvironments, remains a major challenge for scalable disease modeling and therapeutic evaluation.
Jungseub Lee, Wooju Park, Sujin Hyung, Sangmin Jung, Kyungho Lee, Junseok Jeon, Noo Li Jeon, Jeeyun Lee, Hye Ryoun Jang, Jihoon Ko   +9 more
wiley   +1 more source