Results 131 to 140 of about 57,799 (256)
ABSTRACT The approval requirements in new regions that do not require domestic clinical data and the clinical data evaluation of multi‐regional clinical trials (MRCTs) and foreign clinical trials (FCTs) in the Japanese approval review processes for antimicrobial medicines were explored.
Rumiko Shimazawa, Masayuki Ikeda
wiley +1 more source
Pyroptosis is a proinflammatory programmed cell death (PCD) that protects the host against invading viruses. We previously reported that pyroptosis plays a prominent role in the pathogenesis of murine cytomegalovirus (MCMV) retinal necrosis using mice ...
Jessica J. Carter +3 more
doaj +1 more source
The endoplasmic reticulum membrane protein complex (EMC) is an evolutionarily conserved, multi‐subunit transmembrane protein complex crucial to membrane protein biogenesis and cellular protein quality control. This review systematically examines the structure, functions and disease‐associated regulatory mechanisms of EMC across multiple organ systems ...
Yan Qiao +6 more
wiley +1 more source
A laser flare-cell meter was used to examine blood-aqueous barrier function in a 21-year-old male patient who had typical retinitis punctata albescens with white dots scattered throughout large areas of the fundus in both eyes.
陳慕師;張慶忠;方怡謨;鄭敏蟬;侯平康 +1 more
core
Neurological disorders are hard to treat. Stem cell‐derived neural organoids enable research, and their transplantation aids CNS therapy, with this article reviewing relevant advances, challenges and prospects. ABSTRACT Neurological disorders are often devastating and notoriously difficult to repair, creating an urgent need for novel research models ...
Yutong Wang +8 more
wiley +1 more source
Presenting Symptom: Visual field constriction. Pathology: Pigmentary retinopathy. Clinical: Although occurring usually as a solitary entity, retinitis pigmentosa may be associated with several systemic hereditary conditions: deafness, cerebellar ...
David G. Cogan, MD (1908-1993)
core
Treatment of cytomegalovirus retinitis
Cytomegalovirus retinitis is an inflammatory necrotic disease of the retina that can have a rapidly progressing course. Patients suffering from acquired immunodeficiency syndrome and recipients of organs or hematopoietic stem cells are most susceptible ...
B. S. Pershin +2 more
core +1 more source
Serological screening for cytomegalovirus in a leucodepleted blood supply: A systematic review
Abstract Background and Objectives Cytomegalovirus (CMV) causes harm in at‐risk populations. Selection of seronegative donors has been used to prevent transmission. Leucodepletion reduces the potential for CMV transmission; however, the residual risk is uncertain, leading to variability in practice.
Philip J. Crispin +7 more
wiley +1 more source
A case of bilateral presumed chikungunya neuroretinitis
Chikungunya fever is a relatively rare from of vector-borne viral fever caused by chikungunya virus and spread by bites of the Aedes aegypti and Aedes albopictus mosquito.
Mahesh G +4 more
doaj
Novel codon 15 RHO gene mutation associated with retinitis pigmentosa
Manuel AP Vilela,1 Roberta K Menna Barreto,2 Pedro K Menna Barreto,1 Juliana MF Sallum,3 Vanessa S Mattevi1 1Department of Ophthalmology, Federal Health Sciences University of Porto Alegre, Porto Alegre, Brazil; 2Medical School, Federal University ...
Mattevi VS +4 more
core

