Results 31 to 40 of about 47,593 (212)
The Role of Human Herpesvirus-6 (HHV-6) in General Pathology and Ocular Inflammatory Disorders
Российский офтальмологический журнал, 2018 The paper summarizes current data on HHV-6: prevalence, modes of transmission, clinical manifestations of the primary infection and the reactivation of chronic infection, the role played in the pathogenesis of lymphoproliferative diseases, malignant ...
G. I. Krichevskaya
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Prominent Movement Disorders in RNU2‐2‐Related Spliceosomopathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Pediatric movement disorders often overlap with neurodevelopmental diseases, suggesting shared molecular mechanisms. Variants in small nuclear RNA (snRNA) genes encoding spliceosome components have recently been associated with neurodevelopmental disorders, termed “RNUopathies.” We analyzed genome sequencing data from 14 patients with ...
Magdalena Krygier +6 more
wiley +1 more source
Delhi Journal of Ophthalmology, 2021 Retinitis is one of the common presentation of posterior uveitis. The cause could be either an infection or inflammation but until proven otherwise, retinitis is infectious.
Anamika Patel, Mudit Tyagi
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Retinal remodeling in human retinitis pigmentosa
Experimental Eye Research, 2016 Retinitis Pigmentosa (RP) in the human is a progressive, currently irreversible neural degenerative disease usually caused by gene defects that disrupt the function or architecture of the photoreceptors. While RP can initially be a disease of photoreceptors, there is increasing evidence that the inner retina becomes progressively disorganized as the ...
Jones, B.W. +5 more
openaire +2 more sources
Advanced Materials Interfaces, EarlyView.Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley +1 more source
Indian Journal of Medical and Paediatric OncologyCytomegalovirus (CMV) retinitis is one of the common complications in profoundly immunosuppressed patients such as those with acquired immune deficiency syndrome. It has been rarely reported in patients with lymphoma on aggressive chemotherapy.
Fen Saj +6 more
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Treatment of cytomegalovirus retinitis with an intraocular sustained-release ganciclovir implant
Brazilian Journal of Medical and Biological Research, 2000 The objective of this prospective study was to evaluate the efficacy and complications of the use of an intraocular sustained-release ganciclovir implant for the treatment of active cytomegalovirus (CMV) retinitis in AIDS patients. Thirty-nine eyes of 26
C. Muccioli, R. Belfort Jr.
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Retinal imaging in inherited retinal diseases
Annals of Eye Science, 2020 Inherited retinal diseases (IRD) are a leading cause of blindness in the working age population. The advances in ocular genetics, retinal imaging and molecular biology, have conspired to create the ideal environment for establishing treatments for IRD, with the first approved gene therapy and the commencement of multiple therapy trials.
Georgiou, Michalis +2 more
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Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing
Advanced Science, EarlyView.Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale +6 more
wiley +1 more source
Advanced Science, EarlyView.Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li +23 more
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