Results 101 to 110 of about 60,185 (237)
Phosphodiesterase 3 inhibitors boost bone outgrowth
British Journal of Pharmacology, EarlyView.Background and Purpose C‐type natriuretic peptide (CNP) stimulates skeletal growth by acting on the growth plates of long bones, and a CNP variant is clinically used for achondroplasia treatment. We previously reported that CNP stimulates the autonomic Ca2+ influx mediated by TRPM7 channels in growth plate chondrocytes to facilitate extracellular ...
Takaaki Kawabe +11 more
wiley +1 more source
Acta ophthalmologica, 2018 To investigate flow area changes measured using optical coherence tomography angiography (OCTA; RTVue XR Avanti®) in patients with retinitis pigmentosa (RP) with preserved visual acuity (VA).
S. Takagi +7 more
semanticscholar +1 more source
Clinical &Experimental Ophthalmology, EarlyView.ABSTRACT Background To assess the safety and stability profile of the suprachoroidal retinal prosthesis (ScRP) in participants with retinitis pigmentosa (RP) for 2 years from implantation. Methods Four participants, with advanced RP and bare‐light perception vision were enrolled in a prospective, single arm unmasked interventional clinical trial and ...
Penelope J. Allen +14 more
wiley +1 more source
Clinical &Experimental Ophthalmology, EarlyView.ABSTRACT Background In the last two decades, over 250 000 refugees and asylum seekers have arrived in Australia, many of whom experience significant health problems. Information about their eye health is scarce, particularly for those detained offshore. This is the first study to explore the eye health and services available to this population, helping
Marcel M. Nejatian +3 more
wiley +1 more source
ATYPICAL RETINITIS PIGMENTOSA ASSOCIATED WITH OBESITY, POLYDACTYLY, HYPOGENITALISM, AND MENTAL RETARDATION (THE LAURENCE-MOON-BIEDL SYNDROME) (Clinical and Genealogical Notes on a Case) [PDF]
, 1935 Liliana Savin
openalex +1 more source
Retinitis pigmentosa-associated cystoid macular oedema: pathogenesis and avenues of intervention
British Journal of Ophthalmology, 2016 Hereditary retinal diseases are now the leading cause of blindness certification in the working age population (age 16–64 years) in England and Wales, of which retinitis pigmentosa (RP) is the most common disorder.
S. Strong +4 more
semanticscholar +1 more source
Monogenic Retinal Diseases Associated With Genes Encoding Phototransduction Proteins: A Review
Clinical &Experimental Ophthalmology, Volume 53, Issue 3, Page 260-280, April 2025.ABSTRACT Phototransduction, the process by which captured photons elicit electrical changes in retinal rod and cone cells, represents the first neuronal step in vision and involves interactions between several highly specialised proteins. Pathogenic variants in genes encoding many of these proteins can give rise to significant vision impairment ...
Wendy M. Wong, Omar A. Mahroo
wiley +1 more source
MICROSCOPIC OBSERVATIONS IN A CASE OF RETINITIS PIGMENTOSA [PDF]
, 1931 F. H. VERHOEFF
openalex +1 more source
Clinical Genetics, Volume 107, Issue 6, Page 600-611, June 2025.This study provides clinical practice guidelines to streamline genetic testing for inherited retinal dystrophies (IRDs), underscoring the critical role of molecular diagnosis in enhancing patient care. These recommendations aim to elevate diagnostic accuracy, guide therapeutic decisions, and ultimately improve patient outcomes, marking a significant ...
João Pedro Marques +6 more
wiley +1 more source