Results 11 to 20 of about 60,185 (237)

Discovery of GLO1 New Related Genes and Pathways by RNA-Seq on A2E-Stressed Retinal Epithelial Cells Could Improve Knowledge on Retinitis Pigmentosa

Antioxidants, 2020
Endogenous antioxidants protect cells from reactive oxygen species (ROS)-related deleterious effects, and an imbalance in the oxidant/antioxidant systems generates oxidative stress.
Luigi Donato, Concetta Scimone, Simona Alibrandi, Giacomo Nicocia, Carmela Rinaldi, Antonina Sidoti, Rosalia D’Angelo   +6 more
doaj   +2 more sources

Retinitis Pigmentosa: Current Clinical Management and Emerging Therapies

International Journal of Molecular Sciences, 2023
Retinitis pigmentosa (RP) comprises a group of inherited retinal dystrophies characterized by the degeneration of rod photoreceptors, followed by the degeneration of cone photoreceptors.
Xuan-Thanh-An Nguyen, Lude Moekotte, A. Plomp, A. Bergen, M. V. van Genderen, C. Boon   +5 more
semanticscholar   +1 more source

Retinitis Pigmentosa: Novel Therapeutic Targets and Drug Development

Pharmaceutics, 2023
Retinitis pigmentosa (RP) is a heterogeneous group of hereditary diseases characterized by progressive degeneration of retinal photoreceptors leading to progressive visual decline.
K. Y. Wu, Merve Kulbay, Dana Toameh, A. Xu, Ananda Kalevar, S. Tran   +5 more
semanticscholar   +1 more source

Changes in Retinal Sensitivity Associated With Cotoretigene Toliparvovec in X-Linked Retinitis Pigmentosa With RPGR Gene Variations

JAMA ophthalmology, 2023
This post hoc analysis of the XIRIUS and XOLARIS studies investigates how changes in visual function associated with cotoretigene toliparvovec gene therapy in participants with RPGR-variant X-linked retinitis pigmentosa compare with those of untreated ...
Lenore Soodak von Krusenstiern, Jiajun Liu, Eileen Liao, J. Gow, Guo Chen, Tuyen Ong, A. Lotery, A. Jalil, B. Lam, R. MacLaren   +9 more
semanticscholar   +1 more source

Bilateral Retinitis Pigmentosa with Bilateral Microphakia: An Uncommon Association

Delhi Journal of Ophthalmology, 2022
A series of progressive inherited retinal dystrophies known as retinitis pigmentosa include degeneration of rods followed by the loss of cone photoreceptors.
Anupriya Aggarwal, Rajwinder Kaur, Balbir Khan, Priyanka Dahiya   +3 more
doaj   +1 more source

Retinitis Pigmentosa: Progress in Molecular Pathology and Biotherapeutical Strategies

International Journal of Molecular Sciences, 2022
Retinitis pigmentosa (RP) is genetically heterogeneous retinopathy caused by photoreceptor cell death and retinal pigment epithelial atrophy that eventually results in blindness in bilateral eyes.
Wanqin Liu, Shan-pei Liu, Ping Li, Kai Yao   +3 more
semanticscholar   +1 more source

Retinitis Pigmentosa: Burden of Disease and Current Unmet Needs

Clinical Ophthalmology, 2022
Retinitis Pigmentosa (RP), a group of inherited retinal dystrophies characterised by progressive vision loss, is the leading cause of visual disability and blindness in subjects less than 60 years old. Currently incurable, therapy is aimed at restricting
Nancy Cross, Cécile van Steen, Y. Zegaoui, A. Satherley, Luigi Angelillo   +4 more
semanticscholar   +1 more source

Long-Term Visual Field Progression in X-Linked Retinitis Pigmentosa Patients. [PDF]

Diagnostics (Basel)
We present an image that illustrates long-term visual field progression in patients with X-linked retinitis pigmentosa (XLRP) due to the retinitis pigmentosa GTPase regulator (RPGR) and retinitis pigmentosa 2 protein (RP2) gene variants.
Steensberg AH, Al-Hamdani S, Hansen MS, Klefter ON, Bertelsen M, Hamann S.   +5 more
europepmc   +2 more sources

Ocular biometry with swept-source optical coherence tomography-based optical biometer in Japanese patients with EYS-related retinitis pigmentosa: a retrospective study

BMC Ophthalmology, 2022
Background This study aimed to identify the features of ocular biometry in patients with EYS-related retinitis pigmentosa using IOLMaster 700. Methods We retrospectively reviewed the medical records of patients with retinitis pigmentosa.
Daiki Sakai, Satoshi Yokota, Akiko Maeda, Yasuhiko Hirami, Makoto Nakamura, Yasuo Kurimoto   +5 more
doaj   +1 more source

Light-induced charge generation in polymeric nanoparticles restores vision in advanced-stage retinitis pigmentosa rats

Nature Communications, 2022
Retinal dystrophies such as Retinitis pigmentosa are among the most prevalent causes of inherited legal blindness, for which treatments are in demand. Retinal prostheses have been developed to stimulate the inner retinal network that, initially spared by
S. Francia, D. Shmal, S. Di Marco, G. Chiaravalli, J. F. Maya-Vetencourt, G. Mantero, C. Michetti, S. Cupini, G. Manfredi, M. L. DiFrancesco, A. Rocchi, S. Perotto, M. Attanasio, R. Sacco, S. Bisti, M. Mete, G. Pertile, G. Lanzani, E. Colombo, F. Benfenati   +19 more
semanticscholar   +1 more source