Results 21 to 30 of about 60,185 (237)
Cone photoreceptor dysfunction in retinitis pigmentosa revealed by optoretinography
Proceedings of the National Academy of Sciences of the United States of America, 2021 Significance Many blinding diseases afflict photoreceptors, specialized cells in the retina that capture and transduce light to initiate vision. Biomarkers that are sensitive to photoreceptor health are crucial for early detection and effective treatment
Ayoub Lassoued +6 more
semanticscholar +1 more source
Molecular Mechanisms Related to Oxidative Stress in Retinitis Pigmentosa
Antioxidants, 2021 Retinitis pigmentosa (RP) is an inherited retinopathy. Nevertheless, non-genetic biological factors play a central role in its pathogenesis and progression, including inflammation, autophagy and oxidative stress.
C. Gallenga +7 more
semanticscholar +1 more source
Retinitis pigmentosa: A Case Report with Thr17Arg as a Novel Mutation in RHO Gene. [PDF]
Journal of Epigenetics, 2022 Background and Aim: Retinitis pigmentosa (RP) is the most common type of inherited progressive photoreceptor cells degeneration causing night blindness, progressive reduction of visual field, loss of retinal pigment epithelial function, and ultimately ...
sajjad Rafiee Komachali +2 more
doaj +1 more source
A novel mutation in PRPF31, causative of autosomal dominant retinitis pigmentosa, using the BGISEQ-500 sequencer [PDF]
International Journal of Ophthalmology, 2018 AIM: To study the genes responsible for retinitis pigmentosa. METHODS: A total of 15 Chinese families with retinitis pigmentosa, containing 94 sporadically afflicted cases, were recruited. The targeted sequences were captured using the Target_Eye_365_V3
Yu Zheng +11 more
doaj +1 more source
Müller glial responses compensate for degenerating photoreceptors in retinitis pigmentosa
Experimental and Molecular Medicine, 2021 Photoreceptor degeneration caused by genetic defects leads to retinitis pigmentosa, a rare disease typically diagnosed in adolescents and young adults.
Yohei Tomita +7 more
semanticscholar +1 more source
Coincidence of retinitis pigmentosa and pseudoexfoliative glaucoma [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2017 Introduction. This is an observational case report presenting retinitis pigmentosa associated with pseudoexfoliative glaucoma. Case outline. A 69-year-old man presented with retinitis pigmentosa. On examination, pseudoexfoliative material was detected on
Božić Marija +3 more
doaj +1 more source
Retinitis Pigmentosa Unilateral: Reporte de 2 Casos.
Revista Oftálmica, 2021 Objetivo: Reportar 2 casos clínicos con diagnóstico de Retinitis Pigmentosa Unilateral. Caso Clínico: Se presentan 2 casos con Retinitis, Pigmentosa unilateral.
Fernando Salvador Cifuentes y Cifuentes
doaj +1 more source
Altered antioxidant-oxidant status in the aqueous humor and peripheral blood of patients with retinitis pigmentosa. [PDF]
PLoS ONE, 2013 Retinitis Pigmentosa is a common form of hereditary retinal degeneration constituting the largest Mendelian genetic cause of blindness in the developed world. It has been widely suggested that oxidative stress possibly contributes to its pathogenesis. We
Cristina Martínez-Fernández de la Cámara +9 more
doaj +1 more source
Nature Network Boston, 2020 Retinal gene therapy has shown great promise in treating retinitis pigmentosa (RP), a primary photoreceptor degeneration that leads to severe sight loss in young people.
J. Cehajic-Kapetanovic +25 more
semanticscholar +1 more source