Results 51 to 60 of about 53,967 (228)

Macular Hole of the Left Eye in a 41-year-old Patient with Retinitis pigmentosa. A Case Report

Okulistyka
Retinitis pigmentosa is characterized by degeneration of the photoreceptors or retinal pigment epithelium and causes progressive vision loss. The disease can lead to night blindness, reduced field of vision and finally to complete loss of vision.
Bożena Kmak, Tomasz Siewierski, Anna Szot, Sebastian Sirek   +3 more
doaj   +1 more source

A novel small molecule chaperone of rod opsin and its potential therapy for retinal degeneration

Nature Communications, 2018
Mutations that lead to misfolding of rhodopsin can cause retinitis pigmentosa. Here, the authors carry out a high throughput screen to identify a small molecule chaperone of rod opsin, and show that it protects mouse models of retinitis pigmentosa from ...
Yuanyuan Chen, Yu Chen, Beata Jastrzebska, Marcin Golczak, Sahil Gulati, Hong Tang, William Seibel, Xiaoyu Li, Hui Jin, Yong Han, Songqi Gao, Jianye Zhang, Xujie Liu, Hossein Heidari-Torkabadi, Phoebe L. Stewart, William E. Harte, Gregory P. Tochtrop, Krzysztof Palczewski   +17 more
doaj   +1 more source

A flexible arched artificial photoreceptor constructed by photodeformable liquid crystal polymers and its application in vision restoration

Smart Molecules, EarlyView.
A flexible arched artificial photoreceptor with high stability and biocompatibility was fabricated by integrating liquid crystal polymers with polyvinylidene fluoride‐trifluoroethylene. This device exhibits robust photoelectric responses under low‐intensity illumination and demonstrates efficacy in restoring visual responses in blind rats following ...
Yumeng Jiang, Bo Peng, Jinyu Ma, Feng Pan, Jia Wei, Lang Qin, Cheng Sun, Yanlei Yu   +7 more
wiley   +1 more source

Amino acids in retinitis pigmentosa

Indian Journal of Ophthalmology, 1988
Retinitis pigmentosa may be associated with amino acid′ disorders; whether the association is incidental or consequential is not known. The present investigation on amino acids in retinitis pigmentosa indicates that the level of plasma amino acids
Singh M
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ARL3 mutations cause Joubert syndrome by disrupting ciliary protein composition [PDF]

, 2018
Joubert syndrome (JBTS) is a genetically heterogeneous autosomal recessive neurodevelopmental ciliopathy. We investigated further the underlying genetic etiology of Joubert syndrome by studying two unrelated families in whom JBTS was not associated ...
Alhashem, Amal, Alkanderi, Sumaya, Alkuraya, Fowzan S., Cairns, George, Edwards, Noel, Elmaghloob, Yasmin, Ewida, Nour, Ismail, Shehab, Miles, Colin G., Molinari, Elisa, Ramsbottom, Simon A., Rice, Sarah J., Sammut, Veronica, Sayer, John A., Shaheen, Ranad, Srivastava, Shalabh, Steel, David H., Stephen, Louise A., White, Kathryn   +18 more
core   +1 more source

Retinal Hemodynamics in Retinitis Pigmentosa

American Journal of Ophthalmology, 1996
To investigate the retinal hemodynamic changes occurring in patients with retinitis pigmentosa (RP).Bidirectional laser Doppler velocimetry and monochromatic fundus photography were used to determine retinal venous diameter (D), maximum erythrocyte velocity (Vmax), and volumetric blood flow (Q) in the major retinal veins of eight patients with RP and ...
J E, Grunwald, A M, Maguire, J, Dupont
openaire   +2 more sources

Mesopic microperimetry in Stargardt disease: Application and reliability

Acta Ophthalmologica, EarlyView.
Abstract Purpose Mesopic microperimetry (mMP) is a promising functional endpoint in clinical trials for Stargardt disease type 1 (STGD1). This study evaluated the test–retest variability of mMP and influencing factors, which is essential for ensuring reliability in future STGD1 trials.
Sybren H. Kootstra, Jeroen A. A. H. Pas, Patty P. A. Dhooge, Steffen Schmitz‐Valckenberg, Maurizio Battaglia Parodi, Philipp Herrmann, Frank G. Holz, Andrew J. Lotery, Katarina Stingl, Thomas H. Wheeler‐Schilling, Camiel J. F. Boon, Carel B. Hoyng, Soraprazan Consortium   +12 more
wiley   +1 more source

Comparison of 5-year progression of retinitis pigmentosa involving the posterior pole among siblings by means of SD-OCT: a retrospective study [PDF]

, 2018
The blockchain technology promises to transform finance, money and evengovernments. However, analyses of blockchain applicability and robustness typicallyfocus on isolated systems whose actors contribute mainly by running the consensusalgorithm. Here, we
A Hagiwara, A Schatz, AF Wright, AH Hariri, Andi Abeshi, Barbara Sala, BJ Keats, C Bunker, CA Adackapara, CO Pierrottet, CX Cai, DA Bessant, DB Farber, DG Birch, DT Hartong, E Strettoi, E Zrenner, F Testa, Fabio Patelli, GA Fishman, Giovanni Montesano, GM Acland, H Chung, H Hirakawa, H JR, HS Uy, J Sahel, JW Bainbridge, K Holopigian, L Dacruz, L Gränse, Leonardo Colombo, LH Lima, Luca Rossetti, M Haim, Matteo Bertelli, MS Humayun, Paolo Maltese, RP McNabb, S Bundey, S Grover, SG Jacobson, SP Daiger, T Léveillard, T Léveillard, T Sujirakul, V Busskamp, V Kitiratschky, VG Grigoropoulos, W Berger, W Seiple, Y He, Y Makiyama   +52 more
core   +1 more source

The oscillatory response of the electroretinogram and neuronal adaptation

Acta Ophthalmologica, EarlyView.
Abstract After more than 50 years, there still remains a challenge and an interest to know more as well as extend and deepen our understanding of the small rapid wavelets, the oscillatory potentials (OPs), of the electroretinogram (ERG) and the neuronal adaptation of the retina.
Lillemor Wachtmeister, Anders Eklund
wiley   +1 more source

Retinitis pigmentosa and congenital toxoplasmosis: A rare coexistence

Indian Journal of Ophthalmology, 2007
We describe a previously unreported co-existence of retinitis pigmentosa and congenital toxoplasmosis. An eight year old male presented to our center with complaints of decreased night vision.
Chhabra Manpreet, Prakash Gunjan, Vashisht Nagender, Garg S   +3 more
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