Results 81 to 90 of about 60,943 (273)

Fluorescence Lifetime Imaging Techniques—A Review on Principles, Applications and Clinical Relevance

Journal of Biophotonics, EarlyView.
This article gives an overview of the most frequently used fluorescence‐lifetime imaging (FLIM) techniques, their capabilities and typical applications in biology and clinical studies. ABSTRACT This article gives an overview of the most frequently used fluorescence‐lifetime imaging (FLIM) techniques, their capabilities, and typical applications ...
V. I. Shcheslavskiy, M. V. Shirmanova, K. S. Yashin, A. C. Rück, M. C. Skala, W. Becker   +5 more
wiley   +1 more source

Retinitis pigmentosa and congenital toxoplasmosis: A rare coexistence

Indian Journal of Ophthalmology, 2007
We describe a previously unreported co-existence of retinitis pigmentosa and congenital toxoplasmosis. An eight year old male presented to our center with complaints of decreased night vision.
Chhabra Manpreet, Prakash Gunjan, Vashisht Nagender, Garg S   +3 more
doaj  

The Role of the Endothelin System in the Vascular Dysregulation Involved in Retinitis Pigmentosa

Journal of Ophthalmology, 2015
Retinitis pigmentosa is a clinical and genetic group of inherited retinal disorders characterized by alterations of photoreceptors and retinal pigment epithelium leading to a progressive concentric visual field restriction, which may bring about severe ...
Francesco Saverio Sorrentino, Claudio Bonifazzi, Paolo Perri   +2 more
doaj   +1 more source

Autophagy Dysfunction and Oxidative Stress, Two Related Mechanisms Implicated in Retinitis Pigmentosa

Frontiers in Physiology, 2018
Retinitis pigmentosa (RP) is one of the most common clinical subtypes of retinal degeneration (RD), and it is a neurodegenerative disease that could cause complete blindness in humans because it ultimately affects the photoreceptors viability.
Mari-Luz Moreno, Salvador Mérida, F. Bosch-Morell, M. Miranda, V. M. Villar   +4 more
semanticscholar   +1 more source

The Genetic Basis of Pericentral Retinitis Pigmentosa—A Form of Mild Retinitis Pigmentosa [PDF]

Genes, 2017
Pericentral retinitis pigmentosa (RP) is an atypical form of RP that affects the near-peripheral retina first and tends to spare the far periphery. This study was performed to further define the genetic basis of this phenotype. We identified a cohort of 43 probands with pericentral RP based on a comprehensive analysis of their retinal phenotype ...
Comander, Jason, Maher, Matthew, Place, Emily, Sandberg, Michael, Pierce, Eric, Weigel-DiFranco, Carol, Wan, Aliete, Harper, Shyana, Navarro-Gomez, Daniel   +8 more
openaire   +4 more sources

Vascular dysfunction in retinitis pigmentosa

Acta ophthalmologica, 2019
The relationship between ocular haemodynamics and retinitis pigmentosa (RP) has not been fully understood. Reductions in blood flow have been established in RP patients by a variety of studies; however, questions have yet to be answered regarding the ...
Matt Lang, A. Harris, T. Ciulla, B. Siesky, Pooja Patel, Aditya V. Belamkar, S. Mathew, A. V. Verticchio Vercellin   +7 more
semanticscholar   +1 more source

Retinitis pigmentosa‐1 due to an RP1 mutation in a consanguineous Iranian family: Report of a novel mutation

Clinical Case Reports
Key Clinical Message The identification of a novel RP1 gene mutation highlights the importance of precise variant identification for retinitis pigmentosa prognosis and genetic consultations, emphasizing comprehensive genetic analysis for personalized ...
Mostafa Neissi, Motahareh Sheikh‐Hosseini, Javad Mohammadi‐Asl   +2 more
doaj   +1 more source

Bardet Biedl syndrome – report of a very rare case

National Journal of Clinical Anatomy, 2016
Bardet Biedl Syndrome is a autosomal recessive condition with a wide spectrum of clinical features. The principal manifestations of the syndrome are Post axial Polydactyly, Retinitis Pigmentosa, truncal obesity, hypogonadism & renal dysfunction.
Asha Shirahatti, Daksha Dixit, Harshavardhan Pati   +2 more
doaj   +1 more source

Visual Cortical Plasticity in Retinitis Pigmentosa

Investigative Ophthalmology and Visual Science, 2019
Purpose Retinitis pigmentosa is a family of genetic diseases inducing progressive photoreceptor degeneration. There is no cure for retinitis pigmentosa, but prospective therapeutic strategies are aimed at restoring or substituting retinal input.
C. Lunghi, L. Galli‐Resta, Paola Binda, G. Cicchini, G. Placidi, B. Falsini, M. Morrone   +6 more
semanticscholar   +1 more source

Update on Gene Therapy in the Treatment of Hereditary Hearing Loss

Sensory Neuroscience, EarlyView.
Gene therapy is a promising therapeutic approach for genetic disorders, including three major gene therapy strategies: gene replacement, gene suppression, and gene editing. After transmitting genes to the inner ear through appropriate pathways, repair the cochlea in order to achieve the goal of treating hereditary hearing loss.
Weiwei He, Shanying Han, Xinghong Liu, Xiaotong Huang, Wen Yang, Xinghua Tang, Chuan Dong, Jiangang Fan   +7 more
wiley   +1 more source