Results 341 to 350 of about 390,951 (380)
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Induction of retinoic acid receptor-beta by retinoic acid is cell specific.
Endocrinology, 1993The retinoic acid (RA) receptor-beta (RAR beta) gene is dramatically up-regulated by RA in F9 teratocarcinoma cells due to the presence of an RA-responsive element (RARE) in its promoter. Remarkably, however, RAR beta mRNA was essentially unaffected by RA in rat pituitary GH3 cells, even though the GH gene was induced by RA, and these cells express ...
Mitchell A. Lazar, Kelly D. Davis
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Molecular Endocrinology, 1989
The thyroid hormones and retinoic acid are potent modulators of differentiation, development, and gene expression. The transcriptional activities of these ligands are mediated by closely related nuclear receptors which bind and activate identical hormone
B. M. Forman +5 more
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The thyroid hormones and retinoic acid are potent modulators of differentiation, development, and gene expression. The transcriptional activities of these ligands are mediated by closely related nuclear receptors which bind and activate identical hormone
B. M. Forman +5 more
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Mechanisms of transcriptional activation by retinoic acid receptors
Biochemical Society Transactions, 1997International ...
Glass, C. +8 more
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Identification of a second human retinoic acid receptor
Nature, 1988We have previously described a human complementary DNA that encodes a novel protein which is homologous to members of the steroid/thyroid nuclear receptor multigene family. This novel protein (hap for hepatoma) exhibits strong homology with the human retinoic acid receptor (RAR) which has been recently characterized.
Brand, Nigel +7 more
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Retinoic acid receptors, hematopoiesis and leukemogenesis
Current Opinion in Hematology, 2008All-trans retinoic acid therapy of acute promyelocytic leukemia represents the most successful example of differentiation-induction therapy in clinical oncology. However, acute promyelocytic leukemia represents only a small minority (10-15%) of the myeloid leukemias.
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Modulation of limb bud chondrogenesis by retinoic acid and retinoic acid receptors.
The International journal of developmental biology, 1995An excess of retinoic acid (RA) in the mouse embryo in utero produces hypochondrogenesis and severe limb bone deformities. Since one of the RA receptors--RAR-beta 2, is specifically induced in the limb bud cells upon treatment of embryos with teratogenic doses of RA, we investigated if this receptor played a role in teratogenesis by regulating the ...
J. D. Penner +6 more
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Effects of retinoic acid on the expression of retinoic acid receptors during zebrafish embryogenesis
Mechanisms of Development, 1994The cDNAs encoding the zebrafish homologs of retinoic acid receptor alpha(zRAR alpha) and gamma (zRAR gamma) were isolated and their expression studied in normal and retinoic acid (RA) treated embryos. Expression boundaries in the central nervous system are clearly different from those observed in the mouse, which can only partly be explained by ...
Gerard B.L.J. van der Lans +6 more
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AIDS, 1994
To analyze the effect of retinoic acids (RA) on HIV-1 expression and correlate this effect with expression levels of RA receptors (RARs) in T-lymphoid and monocytoid cell lines.The effect of all-trans and 9-cis RA on HIV-1 production in T-lymphoid (H9, CEM) and monocytoid (U937,THP-1) cell lines was measured during acute and chronic infection.
Koushi Yamaguchi +2 more
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To analyze the effect of retinoic acids (RA) on HIV-1 expression and correlate this effect with expression levels of RA receptors (RARs) in T-lymphoid and monocytoid cell lines.The effect of all-trans and 9-cis RA on HIV-1 production in T-lymphoid (H9, CEM) and monocytoid (U937,THP-1) cell lines was measured during acute and chronic infection.
Koushi Yamaguchi +2 more
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A decade of molecular biology of retinoic acid receptors
The FASEB Journal, 1996P. Chambon
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Retinoic acid receptors: from molecular mechanisms to cancer therapy.
Molecular Aspects of Medicine, 2015A. di Masi +8 more
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