Results 271 to 280 of about 155,897 (329)

Selective ablation of retinoid X receptor α in hepatocytes impairs their lifespan and regenerative capacity

, 2001
Takeshi Imai, Ming Jiang, Philippe Kastner, Pierre Chambon, Daniel Metzger   +4 more
openalex   +1 more source

Existence of Retinoic Acid-Receptor-Independent Retinoid X-Receptor-Dependent Pathway in Myeloid Cell Function

, 2001
Takayuki Hida, Kenji Tai, Naoki Tokuhara, Akira Ishibashi, K. Kikuchi, Shigeki Hibi, Hiroyuki Yoshimura, Mitsuo Nagai, Toshihiko Yamauchi, Seiichi Kobayashi   +9 more
openalex   +1 more source

The Structural Basis for the Specificity of Retinoid-X Receptor-selective Agonists: New Insights Into the Role of Helix H12

, 2002
James D. Love, John Gooch, Szilvia Benkő, Chuan Li, László Nagy, Krishna Chatterjee, Ronald M. Evans, John W. R. Schwabe   +7 more
openalex   +1 more source

Erratum: Synergistic Effect Of A Retinoid X Receptor-Selective Ligand Bexarotene And Docetaxel In Prostate Cancer [Corrigendum]. [PDF]

Onco Targets Ther, 2019
europepmc   +1 more source

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Retinoid X Receptor Selective Agonists and their Synthetic Methods.

Current Topics in Medicinal Chemistry, 2017
Since the isolation and identification of the retinoid X receptor (RXR) as a member of the nuclear receptor (NR) superfamily in 1990, its analysis has ushered in a new understanding of physiological regulation by nuclear receptors, and novel methods to ...
C. Wagner, P. Jurutka, P. Marshall, Michael C. Heck   +3 more
semanticscholar   +4 more sources

Retinoid X receptors and retinoid response in neuroblastoma cells

Journal of Cellular Biochemistry, 2002
AbstractRetinoic acid (RA) modulates differentiation and apoptosis of neural cells via RA receptors (RARs) and retinoid X receptors (RXRs). Neuroblastoma cells are potentially useful models for elucidating the molecular mechanisms of RA in neural cells, and responses to different isomers of RA have been interpreted in terms of differential homo‐ and ...
Rana, B., Veal, G.J., Pearson, A.D.J., Redfern, C.P.F.   +7 more
openaire   +4 more sources

Retinoids Selective for Retinoid X Receptor Response Pathways

Science, 1992
Retinoids have a broad spectrum of biological activities and are useful therapeutic agents. Their physiological activities are mediated by two types of receptors, the retinoic acid receptors (RARs) and the retinoid X receptors (RXRs). RARs, as well as several related receptors, require heterodimerization with RXRs for effective DNA binding
James F. Cameron, Ling Jong, Magnus Pfahl, Xian Ping Lu, Marcia I. Dawson, Pamela Haefner, Jürgen M. Lehmann, Andrea Fanjul   +7 more
openaire   +3 more sources

ChemInform Abstract: Synthesis of Novel Retinoid X Receptor‐Selective Retinoids.

ChemInform, 2001
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Leonard L. Winneroski, Kevin A. Sullivan, William G. Trankle, Margaret M. Faul, Andrew Michael Ratz   +4 more
openaire   +4 more sources

Identification of an Activator of the Retinoid X Receptor

Journal of Natural Products, 1994
A metabolite of all-trans retinoic acid produced by insect cells was discovered to activate the intracellular retinoic acid X receptor. The compound, beta-glucopyranosyl 9-cis-retinoate [1], was purified and its structure was determined by analysis of spectroscopic data.
Charles Pathirana, Richard A. Heyman, Steven B. Lazarchik   +2 more
openaire   +3 more sources

Retinoid X Receptor Heterodimers in the Metabolic Syndrome

New England Journal of Medicine, 2005
The principal abnormalities of the metabolic syndrome are abdominal obesity, atherogenic dyslipidemia, hypertension, insulin resistance, inflammation, and prothrombotic states.
David J. Mangelsdorf, Andrew I. Shulman
openaire   +6 more sources