Results 51 to 60 of about 2,652,154 (287)

All-Purpose Containers? Lipid-Binding Protein - Drug Interactions. [PDF]

open access: yesPLoS ONE, 2015
The combined use of in vitro (19F-NMR) and in silico (molecular docking) procedures demonstrates the affinity of a number of human calycins (lipid-binding proteins from ileum, liver, heart, adipose tissue and epidermis, and retinol-binding protein from ...
Tiziana Beringhelli   +7 more
doaj   +1 more source

Effects of acute inflammation on plasma retinol, retinol-binding protein, and its mRNA in the liver and kidneys of vitamin A-sufficient rats

open access: yesJournal of Lipid Research, 1996
The acute inflammatory response to tissue injury and infection is associated with low concentrations of plasma retinol and its specific transport proteins, retinol-binding protein (RBP) and transthyretin (TTR).
F J Rosales   +4 more
doaj   +1 more source

A Prognostic Model for In-Hospital Mortality in Critically Ill Patients with Pneumonia

open access: yesInfection and Drug Resistance, 2022
Le Hu,1,2 Ying Zhang,1,2 Jia Wang,1,2 Jingchao Xuan,1,2 Jun Yang,1,2 Junyu Wang,1,2 Bing Wei1,2 1Emergency Medicine Clinical Research Center, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Beijing Key ...
Hu L   +6 more
doaj  

Structural and binding properties of two paralogous fatty acid binding proteins of Taenia solium metacestode.

open access: yesPLoS Neglected Tropical Diseases, 2012
BackgroundFatty acid (FA) binding proteins (FABPs) of helminths are implicated in acquisition and utilization of host-derived hydrophobic substances, as well as in signaling and cellular interactions. We previously demonstrated that secretory hydrophobic
Seon-Hee Kim   +7 more
doaj   +1 more source

Loss of Retinol-Binding Properties for Plasma Retinol-Binding Protein in Normal Human Epidermis

open access: yesJournal of Investigative Dermatology, 1987
Terminal differentiation of the keratinocytes (cornification) has been linked to a restricted supply of retinol. Retinol is distributed to target cells by the retinol-binding protein (RBP), which circulates in the plasma in complex with transthyretin (TTR).
Siegenthaler, Georges   +1 more
openaire   +2 more sources

Retinol and vitamin A metabolites accumulate through RBP4 and STRA6 changes in a psoriasis murine model

open access: yesNutrition & Metabolism, 2020
Background Psoriasis is a common chronic inflammatory skin disease that features the abnormal proliferation of keratinocytes. This proliferation could partly result from disturbances in vitamin A metabolism. Changes in psoriasis patients of the levels of
Hai-meng Wang   +4 more
doaj   +1 more source

Engineered Nanoplatforms Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy via TGF‐β Axis Inhibition and Ferroptosis Induction

open access: yesAdvanced Healthcare Materials, EarlyView.
FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs,
Yinuo Yang   +11 more
wiley   +1 more source

Expression Profiles of Cellular Retinol-binding Protein, Type II (CRBP II) in Erlang Mountainous Chickens [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2014
Cellular retinol-binding protein II (CRBP II) belongs to the family of cellular retinol-binding proteins and plays a major role in absorption, transport, and metabolism of vitamin A.
H. D. Yin   +9 more
doaj   +1 more source

A Pentaradial and Bilateral Combined Photoreception System in the Sea Cucumber is Mediated by a Blue Light‐Sensitive R‐Opsin

open access: yesAdvanced Science, EarlyView.
The sea cucumber Holothuria leucospilota detects blue and adjacent wavelengths of light via an r‐opsin with a maximum absorption at 459 nm. In the oral tentacles, papillae, and tube feet, distinct light‐sensing structures with specialized morphologies are formed, constituting a unique pentaradial and bilateral combined photoreception system.
Jiasheng Huang   +20 more
wiley   +1 more source

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