Results 31 to 40 of about 21,720 (214)

Retinol and vitamin A metabolites accumulate through RBP4 and STRA6 changes in a psoriasis murine model

open access: yesNutrition & Metabolism, 2020
Background Psoriasis is a common chronic inflammatory skin disease that features the abnormal proliferation of keratinocytes. This proliferation could partly result from disturbances in vitamin A metabolism. Changes in psoriasis patients of the levels of
Hai-meng Wang   +4 more
doaj   +1 more source

Loss of Retinol-Binding Properties for Plasma Retinol-Binding Protein in Normal Human Epidermis

open access: yesJournal of Investigative Dermatology, 1987
Terminal differentiation of the keratinocytes (cornification) has been linked to a restricted supply of retinol. Retinol is distributed to target cells by the retinol-binding protein (RBP), which circulates in the plasma in complex with transthyretin (TTR).
Siegenthaler, Georges   +1 more
openaire   +2 more sources

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Expression Profiles of Cellular Retinol-binding Protein, Type II (CRBP II) in Erlang Mountainous Chickens [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2014
Cellular retinol-binding protein II (CRBP II) belongs to the family of cellular retinol-binding proteins and plays a major role in absorption, transport, and metabolism of vitamin A.
H. D. Yin   +9 more
doaj   +1 more source

Urinary Proteomics Analysis of Active Vitiligo Patients: Biomarkers for Steroid Treatment Efficacy Prediction and Monitoring

open access: yesFrontiers in Molecular Biosciences, 2022
Vitiligo is a common acquired skin disorder caused by immune-mediated destruction of epidermal melanocytes. Systemic glucocorticoids (GCs) have been used to prevent the progression of active vitiligo, with 8.2–56.2% of patients insensitive to this ...
Yue-Tong Qian   +10 more
doaj   +1 more source

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

open access: yesAdvanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou   +5 more
wiley   +1 more source

Comparison of retinol binding protein 1 with cone specific G-protein as putative effector molecules in cryptochrome signalling

open access: yesScientific Reports
Vision and magnetoreception in navigating songbirds are strongly connected as recent findings link a light dependent radical-pair mechanism in cryptochrome proteins to signalling pathways in cone photoreceptor cells. A previous yeast-two-hybrid screening
Chad Yee   +6 more
doaj   +1 more source

Effects of biomarkers secreted by visceral adipocites on the cardiovascular system

open access: yesАтеросклероз, 2020
The literature review highlights the results of recent studies of the world over the invectigations of biochemical factors secreted by visceral adipocytes and affecting the activity of the cardiovascular system.
V. I. Oblaukhova, Yu. I. Ragino
doaj   +1 more source

Characterization of Three Novel Fatty Acid- and Retinoid-Binding Protein Genes (Ha-far-1, Ha-far-2 and Hf-far-1) from the Cereal Cyst Nematodes Heterodera avenae and H. filipjevi. [PDF]

open access: yesPLoS ONE, 2016
Heterodera avenae and H. filipjevi are major parasites of wheat, reducing production worldwide. Both are sedentary endoparasitic nematodes, and their development and parasitism depend strongly on nutrients obtained from hosts.
Fen Qiao   +10 more
doaj   +1 more source

An Integrative Strategy Delineates Modular Metabolic Remodeling and Potential Therapeutic Targets Across Metabolic Diseases

open access: yesAdvanced Science, EarlyView.
An integrative single‐cell atlas across multiple metabolic diseases reveals coordinated metabolic modules and disease‐shared versus disease‐specific pathway activities. By systematically comparing scoring strategies, a robust RankAve framework is established. Coupled with network analysis and drug‐target prediction, this resource uncovers cross‐disease
Kuan Yang   +10 more
wiley   +1 more source

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