Results 61 to 70 of about 21,717 (210)

Pt‐TiO2 mesoporous nanosystem co‐delivering phlorezin enables synergistic sonodynamic‐chemoimmunotherapy for hepatocellular carcinoma via directly targeting DDX5 and metabolic reprogramming modulation

BMEMat, EarlyView.
Abstract Hepatocellular carcinoma (HCC), ranking as the third leading cause of cancer‐related mortality globally, continues to pose significant therapeutic challenges. Here, we developed an innovative nanosystem, Phl@PT, based on Pt‐TiO2 nanoparticles for the co‐delivery of Phlorezin, presenting a novel approach for HCC treatment through sonodynamic ...
Kairui Liu, Bo Zhang, Yue Wan, Zhiru Yang, Abdusami Abdurahman, Mengxin He, Shengtao Hu, Yi Zhang, Xiaoke Li, Jin Chang, Jun Kang, Liren Liu, Wanghua Liu, Shao Li   +13 more
wiley   +1 more source

Vitamin A metabolism is changed in donors after living-kidney transplantation: an observational study

Lipids in Health and Disease, 2011
Background The kidneys are essential for the metabolism of vitamin A (retinol) and its transport proteins retinol-binding protein 4 (RBP4) and transthyretin.
Henze Andrea, Raila Jens, Kempf Caroline, Reinke Petra, Sefrin Anett, Querfeld Uwe, Schweigert Florian J   +6 more
doaj   +1 more source

Mapping the interactions of dengue virus NS1 protein with human liver proteins using a yeast two-hybrid system: identification of C1q as an interacting partner. [PDF]

PLoS ONE, 2013
Dengue constitutes a global health concern. The clinical manifestation of this disease varies from mild febrile illness to severe hemorrhage and/or fatal hypovolemic shock.
Emiliana M Silva, Jonas N Conde, Diego Allonso, Mauricio L Nogueira, Ronaldo Mohana-Borges   +4 more
doaj   +1 more source

Characterization of structural features of food molten‐globule state proteins: An overview

Food Biomacromolecules, EarlyView.
Abstract During food processing, pH, ionic strength, and temperature drive conformational transitions from native states to partially folded intermediates and fully unfolded states. The molten‐globule (MG) state typically preserves substantial secondary structure but has relaxed tertiary packing, thereby modulating protein solubility, emulsifying ...
Han Peng, Changyu Zhou, Daodong Pan, Jinxuan Cao, Qiang Xia   +4 more
wiley   +1 more source

PPARβ regulates vitamin A metabolism-related gene expression in hepatic stellate cells undergoing activation

Journal of Lipid Research, 2003
Activation of cultured hepatic stellate cells correlated with an enhanced expression of proteins involved in uptake and storage of fatty acids (FA translocase CD36, Acyl-CoA synthetase 2) and retinol (cellular retinol binding protein type I, CRBP-I ...
Karine Hellemans, Krista Rombouts, Erik Quartier, Andrea S. Dittié, Andreas Knorr, Liliane Michalik, Vera Rogiers, Frans Schuit, Walter Wahli, Andrea Geerts   +9 more
doaj   +1 more source

Asymptomatic renal damages in persons with chronic professional exposure to elementary mercury low concentrations [PDF]

Vojnosanitetski Pregled, 2008
Background/Aim. Any forms of mercury have toxic action on the majority of organs, especially kidneys. The major source of professional exposure to mercury are departments for the production of chlorine which use mercury as catode.
Đurić Stevan, Jovanović Dragan, Hrvačević Rajko, Kovačević Zoran, Konjević Marija   +4 more
doaj   +1 more source

The binding protein for retinoic acid from rat testis cytosol: isolation and partial characterization.

Journal of Lipid Research, 1980
This study reports the isolation and partial characterization of a soluble protein with binding specificity for retinoic acid from rat testis cytosol.
A C Ross, N Adachi, D S Goodman
doaj   +1 more source

Retinol binding protein in rat testicular cells [PDF]

Reproduction, 1981
Summary. Cellular retinol-binding protein (CRBP) was identified in the cytosols of cultured Sertoli cells and peritubular cells from the testes of 20-day-old rats. CRBP was not detected in spermatids or spermatocytes obtained from the testes of 60-day-old rats.
J, Huggenvik, M D, Griswold
openaire   +2 more sources

Vitamin A status in healthy women eating traditionally prepared spirulina (Dihé) in the Chad Lake area.

PLoS ONE, 2018
BackgroundChad Lake is a central place in a region with a high prevalence of vitamin A deficiency. Spirulina, a natural source of β-carotene, is traditionally produced and eaten as "Dihé" around Chad Lake.
Imar Djibrine Soudy, Régine Minet-Quinard, Alhadj Djidda Mahamat, Hadjé Fatimé Ngoua, Abdelaziz Arada Izzedine, Abdelsalam Tidjani, Elisabeth Ngo Bum, Céline Lambert, Bruno Pereira, Jehan-François Desjeux, Vincent Sapin   +10 more
doaj   +1 more source

The Retinol Circulating Complex Releases Hormonal Ligands During Acute Stress Disorders

Frontiers in Endocrinology, 2018
Intensive care workers actively participate in very hot debates aiming at defining the true metabolic, hormonal and nutritional requirements of critically ill patients, the contributory roles played by thyroid and retinoid ligands being largely ...
Yves Ingenbleek
doaj   +1 more source