Results 201 to 210 of about 287,241 (300)

Randomized, single‐centre, double‐blinded repeated dose investigation of safety and tolerability of ocular administrations of a novel silica eye drop product in healthy volunteers

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Managing ocular diseases often requires frequent eye drop administration, which can challenge patient compliance. A long‐acting eye drop technology using an amorphous synthetic silica composite was developed to address this. Our study aimed to assess the safety and tolerability of the Silica Eye Drop platform in healthy volunteers over
Aleksandra Poluianova   +5 more
wiley   +1 more source

Diabetic retinopathy in Greenland and Denmark—Can differences in risk factors explain the lower prevalence in Greenland?

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose The prevalence of diabetic retinopathy (DR) is low in Greenland. Factors underlying the low prevalence may potentially protect against the development of DR. Comparing Greenlandic and Danish populations, this register‐based study explored differences in risk factors that may explain differences in DR prevalence.
Jonas Bjørn Skjøth   +4 more
wiley   +1 more source

Infection control in the brain and the eye

open access: yesActa Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester   +2 more
wiley   +1 more source

Mesopic microperimetry in Stargardt disease: Application and reliability

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose Mesopic microperimetry (mMP) is a promising functional endpoint in clinical trials for Stargardt disease type 1 (STGD1). This study evaluated the test–retest variability of mMP and influencing factors, which is essential for ensuring reliability in future STGD1 trials.
Sybren H. Kootstra   +12 more
wiley   +1 more source

Changes in choroidal and retinal thickness 6 months before and during 18 months of orthokeratology lens treatment in myopic children

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To investigate changes in choroidal and retinal thickness before and during myopia control treatment with orthokeratology lenses (OKL) in myopic children. Methods This was a sub‐study of CONTROL and CONTROL2 studies. The present study was a 2‐year, prospective, single‐group interventional study consisting of a 6‐month pre‐treatment ...
P. O. Hansen, F. Møller, T. M. Jakobsen
wiley   +1 more source

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