Results 241 to 250 of about 201,939 (281)

Cerebral Oxygenation During Transition and Amplitude‐Integrated Electroencephalography Signals: An Ancillary Study to the COSGOD‐III Trial

Acta Paediatrica, EarlyView.
ABSTRACT Aim The COSGOD III trial was designed to guide oxygen delivery by cerebral near infrared spectroscopy (NIRS) in preterm neonates during the immediate transition after birth and showed a non‐significant increase of 4.3% in survival without cerebral injury compared to the control group.
Christina Schreiner, Katharina Goeral, Marlene Hammerl, Katrin Klebermass‐Schrehof, Alexander Avian, Vera Neubauer, Ursula Kiechl‐Kohlendorfer, Daniel Pfurtscheller, Elke Griesmaier, Gerhard Pichler   +9 more
wiley   +1 more source

Surviving Extremely Low Birth Weight Infants Have a Higher Risk of ROP in Sub‐Saharan Africa

Acta Paediatrica, EarlyView.
ABSTRACT Aim Retinopathy of prematurity (ROP) risk factors have been investigated in population‐based studies from most global regions. No such studies are available from Sub‐Saharan Africa (SSA), where improved neonatal care is increasing the survival of preterm infants at risk of ROP.
Tshilidzi van der Lecq, Gerd Holmström, Esmè Jordaan, Gugulabatembunamahlubi Kali, Rudzani Muloiwa, Natasha Rhoda, on behalf of the ROPSA Collaborative Group   +6 more
wiley   +1 more source

Development and Content of Core Outcome Sets in Neonatology—A Scoping Review

Acta Paediatrica, EarlyView.
ABSTRACT Aim To identify subgroups of neonates for whom core outcome sets (COS) have been developed, the outcomes that were included and the methods used in their formulation. Methods We performed a scoping review and searched databases in April 2025 for published COS.
Ilari Kuitunen, Panu Kiviranta, Marjut Haapanen, Peter G. Davis   +3 more
wiley   +1 more source

Urinary Calcium and Phosphorus Excretion in Vitamin D‐Sufficient Preterm Infants: Establishing Age‐Specific Normative Data

Acta Paediatrica, EarlyView.
ABSTRACT Aim This study evaluated urinary calcium (Ca) and phosphorus (P) excretion in very low birth weight infants ( < 1500 g, VLBW) without severe morbidity, treated with methylxanthines. Methods Eighty‐one VLBW infants were analysed. Urinary Ca and P and their creatinine ratios were measured biweekly until day 56.
Tomas Matejek, Veronika Pokorna, Vojtech Drahy, Lenka Zaloudkova, Vladimir Palicka, Sylva Skalova   +5 more
wiley   +1 more source

Absence of Evidence of Beneficial Effects of Human Milk‐Based Fortifier: A Bayesian Model‐Averaged Meta‐Analysis

Acta Paediatrica, EarlyView.
ABSTRACT Aim Human milk‐based fortifiers (HMBFs) have been adopted in neonatal care despite limited efficacy data. Our objective was to conduct a Bayesian re‐analysis of the current evidence on the protective effect of HMBF against necrotising enterocolitis (NEC, stage II‐III).
Maurice J. Huizing, Giulia Vizzari, František Bartoš, Giacomo Cavallaro, Maria L. Gianni, Eduardo Villamor   +5 more
wiley   +1 more source

Synthetic microneurotrophins: Neurotrophin receptors for therapeutics of neurodegenerative diseases

British Journal of Pharmacology, EarlyView.
Neurodegenerative disorders are characterised by the chronic progressive degeneration of specific neuronal subtypes, neuroinflammation, myelin damage and synaptic loss. Despite their growing incidence, advancements in effective treatments remain limited, because of lack of knowledge for the aetiology of the diverse pathophysiology to design systematic ...
Ioanna Zota, Theodora Calogeropoulou, Konstantina Chanoumidou, Ioannis Charalampopoulos, Achille Gravanis   +4 more
wiley   +1 more source

Proposal for a Germline Expert Panel to Improve Variant Reclassification in Japan

Cancer Science, EarlyView.
This letter argues that Japan's dependence on a single foreign company for classifying germline variants is delaying critical treatment for cancer patients. The author proposes establishing a national “Germline Expert Panel” to provide independent, timely oversight, and ensure patients receive appropriate care.
Kazuki Yamazawa
wiley   +1 more source

Potential Impact of Parental Origin of Inheritance on the Clinical Presentation of Familial Partial Lipodystrophy Type 2 Syndrome

Clinical Endocrinology, EarlyView.
ABSTRACT Context Familial partial lipodystrophy type 2 (FPLD2) is a rare autosomal dominant disorder caused by pathogenic variants in the LMNA gene. The influence of parental inheritance on clinical presentation has not been fully explored. Objective To investigate the influence of maternal versus paternal inheritance of LMNA variants on the clinical ...
Donatella Gilio, Ozge Besci, Natália Rossin Guidorizzi, Merve Celik Guler, Ilgin Yildirim Simsir, Caterina Pelosini, Giovanni Ceccarini, Korcan Demir, Baris Akinci, Ferruccio Santini, ECLip (European Consortium of Lipodystrophy), Maria Cristina Foss‐Freitas, Elif A. Oral   +12 more
wiley   +1 more source

Real‐World 10‐Year Outcomes of Anti‐VEGF Therapy for Neovascular Age‐Related Macular Degeneration: A Meta‐Analysis

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background This study examines the long‐term effectiveness of anti‐VEGF therapy in managing neovascular age‐related macular degeneration (nAMD). Despite the well‐established short‐term improvements of anti‐VEGF therapy, there is limited data on its continued efficacy over extended periods.
Kimberly Spooner, Geoffrey Broadhead, Samantha Fraser‐Bell, Thomas Hong, James G. Wong, Andrew A. Chang   +5 more
wiley   +1 more source

Development and Validation of a Deep Learning System for the Provision of a District‐Wide Diabetes Retinal Screening Service

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Artificial intelligence (AI) enhanced retinal screening could reduce the impact of diabetic retinopathy (DR), the leading cause of preventable blindness in Australia. This study assessed the performance and validity of a dual‐modality, deep learning system for detection of vision‐threatening diabetic retinopathy (vtDR) in a multi ...
Jason R. Daley, Xingdi Wang, Natalie Ngo, Chee L. Khoo, Peter Heydon, Gerald Liew, Vallimayil Vallayutham, Tobias Kongbrailatpam, Uchechukwu L. Osuagwu, Marko Andric, Wei Xuan, David Simmons, Shweta Kaushik   +12 more
wiley   +1 more source