Results 201 to 210 of about 165,954,653 (289)

Multi-grader validation of the telemedicine retinopathy of prematurity severity score. [PDF]

open access: yesSci Rep
Pratt HW   +18 more
europepmc   +1 more source

Bile acid metabolism and signaling in human and animal health: A One Health perspective

open access: yesiMetaOmics, Volume 3, Issue 3, September 2026.
Bile acids maintain host homeostasis through enterohepatic circulation, microbial transformation, and bile acid receptor signaling, thereby regulating glucose and lipid metabolism, intestinal barrier integrity, and immunity. These effects support human disease intervention and health‐oriented animal production, reducing drug dependence and residue ...
Lei Li   +7 more
wiley   +1 more source

From Common Pathway to Divergent Diseases: Metabolic Aspects of Inborn Errors of CoA Biosynthesis

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.
ABSTRACT Coenzyme A (CoA) biosynthesis is a conserved, dynamically regulated pathway essential for mitochondrial energy production, fatty acid oxidation, lipid biosynthesis and protein acylation. Biallelic variants in PANK2, PPCS, PPCDC, and COASY cause rare inborn errors of CoA biosynthesis, associated with markedly different clinical phenotypes ...
Ivano Di Meo   +3 more
wiley   +1 more source

Amino Acid Metabolism in Health and Disease

open access: yesMedComm, Volume 7, Issue 9, September 2026.
This graphical abstract delineates the multifaceted role of amino acid metabolism in health and disease. It illustrates how amino acids sustain physiological homeostasis across the liver, kidney, brain, heart, intestine, muscle, skeleton, and immune system.
Zhiwei Su   +7 more
wiley   +1 more source

Compound Heterozygous PCDH15 Variants Associated With Cone‐Rod Dystrophy in a Chinese Pedigree

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 9, September 2026.
This study represents the first report suggesting a genotype–phenotype relationship between PCDH15 genetic variants and isolated retinal manifestations absent auditory impairment or syndromic features, thereby providing preliminary evidence that may broaden the mutational spectrum associated with this gene.
Lei Zhang   +7 more
wiley   +1 more source

Association of childhood‐ versus adult‐onset type 1 diabetes in pregnancy with maternal, neonatal, and glycemic control outcomes

open access: yesPregnancy, Volume 2, Issue 5, September 2026.
Abstract Introduction Type 1 diabetes mellitus (T1DM) is associated with heightened risk of adverse pregnancy outcomes. Genetic, immune, cardiometabolic, and psychosocial differences exist between childhood‐ and adult‐onset T1DM, yet how these differences may influence pregnancy outcomes remains poorly understood.
Lucas Miranda‐Martinez   +3 more
wiley   +1 more source

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