Results 81 to 90 of about 19,507 (232)

Sepsis and Antibiotics in Extremely Preterm Infants: Early Empirical Treatment Was Common, While Late‐Onset Sepsis Accounted for Most Cases and Antibiotic Use

Acta Paediatrica, EarlyView.
ABSTRACT Aim The aim was to investigate the incidence of sepsis and use of antibiotics among extremely preterm infants, given the limited number of population‐based studies examining this. Methods This retrospective study in Eastern Denmark included all liveborn infants from 23 + 0 weeks/days to 27 + 6 weeks/days of gestation from 2019 to 21.
Anna Bjerager Arnesen, Nini Møller, Louise Dyrberg Vibede, Kristian Vestergaard, Sara Krøis Holm, Cæcilie Trier, Hristo Stanchev, Gholamreza Dayani, Ulrikka Nygaard, Bo Mølholm Hansen, Emma Malchau Carlsen   +10 more
wiley   +1 more source

Comprehensive Assessment of the KDM2B‐Associated Neurodevelopmental Disorder and the 12q24.31 Microdeletion Syndrome

Clinical Genetics, EarlyView.
We set out to characterize genotype–phenotype correlations in the recently delineated KDM2B‐associated neurodevelopmental disorder. We observe a highly penetrant CxxC domain‐related phenotype with distinct facial features supported by GestaltMatcher. In contrast, our findings point to variable expressivity and incomplete penetrance of loss‐of‐function ...
Amber S. E. van Oirsouw, Tzung‐Chien Hsieh, Martijn Koetsier, Abdulrazak Alali, Fatimah Albuainain, Elena Bacchelli, Tahsin Stefan Barakat, Yline Capri, Sandra Chantot‐Bastaraud, Valeria Capra, Deanna Alexis Carere, Emma Clement, Nour Elkhateeb, Madeleine Franchi, Jing‐Mei Li, Nicole Matthews, Vanda McNiven, Sarju G. Mehta, Masayuki Nakamura, Chanika Phornphutkul, Nicole Revencu, Marcello Scala, Natalie Shallow, Jennifer Stefanich, Marta Viggiano, Paola Visconti, Susan Walker, Federico Zara, Mariëlle Alders, Bobby P. C. Koeleman, Renske Oegema   +30 more
wiley   +1 more source

A case of retinopathy of prematurity treated by pattern scan laser photocoagulation

Clinical Ophthalmology, 2014
Satoshi Ota, Miho Nozaki, Shuichiro Hirahara, Tomoaki Hattori, Munenori Yoshida, Yuichiro Ogura Department of Ophthalmology and Visual Science, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan Abstract: We experienced a case of
Ota S, Nozaki M, Hirahara S, Hattori T, Yoshida M, Ogura Y   +5 more
doaj  

Real-world scenario of retinopathy of prematurity in Kerala

Kerala Journal of Ophthalmology, 2017
Objective: The objective was to study the incidence and risk factors predisposing to retinopathy of prematurity (ROP) and to assess the outcome after laser photocoagulation. Design: This was a retrospective cohort observational study.
Anubhav Goyal, A Giridhar, Mahesh Gopalakrishnan   +2 more
doaj   +1 more source

Stage‐Associated Microglial Subpopulations and Dynamics in Vascular Pathogenesis of Oxygen‐Induced Retinopathy

Cell Proliferation, EarlyView.
In the oxygen‐induced retinopathy (OIR) mouse model, two distinct microglial subpopulations play opposing roles: highly glycolytic microglia (HGM) promote neovascular formation via Pkm2, while Mrc1/CD206‐positive phagocytosis‐associated microglia (PAM) facilitate its regression.
Yuan Ma, Ziye Chen, Baoyi Liu, Wen Ding, Runping Duan, Kangjie Kong, Zhuojun Xu, Jizhu Li, Jiali Ru, Dianlei Guo, Xiaoyue Wei, Yaping Liu, Zhuangling Lin, Yang Meng, Yuan Liu, Lan Jiang, Zitong Chen, Rebiya Tuxun, Chinling Tsai, Chunqiao Liu, Tao Li   +20 more
wiley   +1 more source

Retinopathy of Prematurity and MicroRNAs

Biomedicines
Retinopathy of Prematurity (ROP), a leading cause of blindness in preterm infants, arises from dysregulated angiogenesis and inflammation. Without timely intervention, ROP can progress to severe outcomes, including dense fibrovascular plaques and retinal detachment.
Albanese, Giuseppe Maria, Visioli, Giacomo, Alisi, Ludovico, Armentano, Marta, Giovannetti, Francesca, Lucchino, Luca, Marenco, Marco, Pontecorvi, Paola, Gharbiya, Magda   +8 more
openaire   +4 more sources

Suppression of Retinal Neovascularisation by Tetrahedral Framework Nucleic Acids‐Resveratrol Via Dual Anti‐Angiogenesis and Anti‐Inflammation

Cell Proliferation, EarlyView.
Resveratrol‐loaded tetrahedral framework nucleic acids (tFNAs‐RSV) enable concurrent anti‐angiogenic and anti‐inflammatory therapy, enhancing ocular delivery and bioactivity. In hypoxia‐induced retinal neovascularisation, tFNAs‐RSV reduce neovascular lesions, vascular leakage and inflammatory infiltration by suppressing HIF‐1, p38 MAPK and NF‐κB p65 ...
Yili Jin, Tao Cai, Junyang Huang, Li Chen, Yi Lin, Jingying Liu, You Wang, Xiaoyan Ding   +7 more
wiley   +1 more source

Zeb2 Controls Retinal Physiological and Pathological Angiogenesis by Regulating Astrocyte Proliferation and Differentiation

Cell Proliferation, EarlyView.
During development, the oxygen‐sensitive transcription factor Zeb2 restrains astrocyte proliferation and maturation to ensure balanced retinal angiogenesis. In disease, it promotes the neurotoxic A1 astrocyte phenotype and inflammation, thereby promoting reparative revascularization over pathological neovascularization.
Jing Liu, Yanan Guo, Kangjian Xiang, Shuyi Wang, Dongchang Xiao, Mengqing Xiang   +5 more
wiley   +1 more source

General movements and neurodevelopmental outcomes at 2 years of age in infants born very preterm

Developmental Medicine &Child Neurology, EarlyView.
This study examines the predictive role of early motor quality in very preterm born infants using the Motor Optimality Score ‐ Revised (MOS‐R). The graphical abstract depicts the link between newborn general movements and cognitive as well as motor outcomes at two years.
Ninib Yakoub, Marieken Asprion, Stephanie Brezina, Tilman Reinelt, Giancarlo Natalucci   +4 more
wiley   +1 more source

Profile of asymmetrical retinopathy of prematurity in twins

Indian Journal of Ophthalmology, 2010
Background: In twin births, both babies have the same gestational age and pre-natal conditions. However, twins may develop a varied retinopathy of prematurity (ROP) course depending on birth weight and other systemic factors.
Azad Rajvardhan, Chandra Parijat, Patwardhan Sourabh, Gupta Aparna   +3 more
doaj