Results 21 to 30 of about 6,473 (203)

Morphological and Molecular Defects in Human Three-Dimensional Retinal Organoid Model of X-Linked Juvenile Retinoschisis [PDF]

, 2019
X-linked juvenile retinoschisis (XLRS), linked to mutations in the RS1 gene, is a degenerative retinopathy with a retinal splitting phenotype. We generated human induced pluripotent stem cells (hiPSCs) from patients to study XLRS in a 3D retinal organoid
Chang, Chia-Ching, Chen, Shih-Jen, Chien, Yueh, Chiou, Shih-Hwa, Huang, Kang-Chieh, Jane, Wann-Neng, Kuo, Jean-Cheng, Lu, Jyh-Feng, Nguyen, Phan Nguyen Nhi, Peng, Chi-Hsien, Schlaeger, Thorsten M., Shi, Michael, Tran, Audrey A., Tsai, Ping-Hsing, Wahlin, Karl J., Wang, Mong-Lien, Wang, Won-Jing, Yang, Tien-Chun, Yarmishyn, Aliaksandr A.   +18 more
core   +2 more sources

A novel mutation in RS1 and clinical manifestations in a Chinese twin family with congenital retinoschisis

Frontiers in Genetics, 2022
Purpose: We aim to analyze the clinical and genetic features in a Chinese family with congenital retinoschisis by whole-exome sequencing and comprehensive clinical examination.Methods: Six members were recruited from a Chinese family.
Xiao-Fang Wang, Fei-Fei Chen, Xin Zhou, Xin-Xuan Cheng, Zheng-Gao Xie   +4 more
doaj   +1 more source

Peripapillary retinoschisis in glaucomatous eyes.

PLoS ONE, 2014
PurposeTo investigate the structural and clinical characteristics of peripapillary retinoschisis observed in glaucomatous eyes using spectral-domain optical coherence tomography (SD-OCT).MethodsCircumpapillary retinal nerve fiber layer (cpRNFL) and ...
Eun Ji Lee, Tae-Woo Kim, Mijin Kim, Yun Jeong Choi   +3 more
doaj   +1 more source

Peripheral fundus findings in X-linked retinoschisis [PDF]

, 2017
BACKGROUND/AIMS: Vitreous haemorrhage (VH) and retinal detachment (RD) cause a precipitous decline in vision in a subset of patients with X-linked retinoschisis (XLRS), an otherwise a slowly progressive condition.
Ali, N, Blachley, T, Fahim, AT, Michaelides, M   +3 more
core   +1 more source

Vitrectomy with peripapillary internal limiting membrane peeling for macular retinoschisis associated with normal-tension glaucoma

American Journal of Ophthalmology Case Reports, 2020
Purpose: Although vitrectomy has been reported to be effective for the treatment of macular retinoschisis associated with glaucoma in a few case series, the surgical techniques have yet to be established.
Keijiro Ishikawa, Takuma Fukui, Shintaro Nakao, Satomi Shiose, Koh-Hei Sonoda   +4 more
doaj   +1 more source

Vitrectomy for macular retinoschisis associated with peripapillary intrachoroidal cavitations in a moderately myopic eye

International Journal of Retina and Vitreous, 2022
Background Peripapillary intrachoroidal cavitation (PICC), a cavernous change in the peripapillary choroid, may present with macular lesions. Here, we present a rare case of PICC with outer lamellar macular hole and macular retinoschisis.
Shuichiro Aoki, Hiroko Imaizumi
doaj   +1 more source

Dehiscence of detached internal limiting membrane in eyes with myopic traction maculopathy with spontaneous resolution [PDF]

, 2012
Background: Idjwi, an island of approximately 220,000 people, is located in eastern DRC and functions semi-autonomously under the governance of two kings (mwamis).
Castro, Marcia C., Greenough, P. Gregg, Hadley, Michael B., Thomson, Dana R.   +3 more
core   +3 more sources

Neovascularization of the iris in retinoschisis

American Journal of Ophthalmology Case Reports, 2017
Purpose: To report the association of rubeosis iridis with chronic bullous degenerative peripheral retinoschisis. Observations: A 63-year-old female presented with acute hyphema and neovascularization of the iris in association with elevated intraocular ...
Geraldine R. Slean, Arthur D. Fu, Judy Chen, Ananda Kalevar   +3 more
doaj   +1 more source

Müller glia provide essential tensile strength to the developing retina. [PDF]

, 2015
This is the final version of the article. It first appeared from the Rockefeller University Press via http://dx.doi.org/10.1083/jcb.201503115To investigate the cellular basis of tissue integrity in a vertebrate central nervous system (CNS) tissue, we ...
Allen, Almeida, Aulehla, Begonia, Bernardos, Bernardos, Bringmann, Byrne, Byrne, Cajal, Christ, Das, Dorsky, Easter, Franze, Franze, Franze, Fratzl, Furukawa, Green, He, Hu, Janmey, Jones, Julia Oswald, Kay, Kettenmann, Kimura, Koser, Kristian Franze, Kroehne, Lindqvist, Lu, Lundkvist, Marmor, Molday, Ninov, Owen Randlett, Parsons, Pasini, Randlett, Rapaport, Reichenbach, Reid, Ryan B. MacDonald, Samuels, Satou, Sauer, Shaw, Shen, Shreiber, Sieger, Straatsma, Swift, Takeshi Yoshimatsu, Taylor, Tomita, Virchow, William A. Harris, Williams, Yeo, Zolessi   +61 more
core   +6 more sources

Bilateral macular holes in X-linked retinoschisis: Now the spectrum is wider

Indian Journal of Ophthalmology, 2011
Bilateral occurrence of macular hole in X-linked retinoschisis is an extremely rare event. Spectral domain optical coherence tomography (OCT) findings revealed that formation of a macular hole is secondary to the retinoschisis process alone.
Manoj Gautam, N S Muralidhar, Hemanth Murthy   +2 more
doaj   +1 more source