Therapy for Myhre Syndrome: Goals, Misconceptions, and Current Agents
ABSTRACT Myhre Syndrome (MYHRS, MIM #139210) is a rare, multisystem connective tissue disorder caused by recurrent heterozygous gain‐of‐function pathogenic variants in the SMAD4 gene, a key player in TGF‐β signaling and a regulator of extracellular matrix homeostasis.
Alessandro De Falco +2 more
wiley +1 more source
Within the same molecular length scale, antiaromatic s‐indacene exhibits a marked increase in conductance compared to its aromatic benzodithiophene counterpart. Notably, the inherently small HOMO–LUMO gap of antiaromatic systems maintains a certain level of conductance even in the presence of cross‐conjugation.
Ching‐Piao Chu +8 more
wiley +2 more sources
Retraction Note: DNA sequence and community structure diversity of multi-year soil fungi in Grape of Xinjiang. [PDF]
Xue F, Liu T.
europepmc +1 more source
Sociodemographic Factors Associated with Hours Worked by Primary Carers in Australia
ABSTRACT Primary caregivers constitute a major unpaid workforce in Australia. The aim of this study was to determine the sociodemographic factors that are associated with carer workloads. Multinomial logistic regression modelling was applied to the nation‐wide Australian Government survey.
Andrew J. Hamilton
wiley +1 more source
3D‐Printable Nanoporous Thermosets via Disulfide‐Based Polymerization‐Induced Microphase Separation
α‐Lipoic acid‐derived degradable macro‐chain transfer agents (macroCTAs) with tunable hydrophilicity drive polymerization‐induced microphase separation (PIMS) in photocurable resins. Selective etching via disulfide cleavage then generates interconnected nanoporous thermosets, and compatibility with liquid‐crystal display (LCD) 3D printing enables the ...
Xueheng Dai +8 more
wiley +2 more sources
RETRACTION: Efficient One-Step Induction of Human Umbilical Cord-Derived Mesenchymal Stem Cells (UC-MSCs) Produces MSC-Derived Neurospheres (MSC-NS) with Unique Transcriptional Profile and Enhanced Neurogenic and Angiogenic Secretomes. [PDF]
International SC.
europepmc +1 more source
In this study, we primarily simulated pathological myocardial remodeling induced by transverse aortic constriction surgery and found significant cardiac hypertrophy and fibrosis, characterized by deteriorated cardiac function. Oxidative stress response is considered as a pivotal pathological process, which contributes to inflammation and apoptosis of ...
Yijia Wang +12 more
wiley +1 more source
Retraction: Health risk assessment of exposure to chlorpyrifos in pregnant women using deterministic and probabilistic approaches. [PDF]
PLOS One Editors.
europepmc +1 more source

