Results 51 to 60 of about 410,068 (315)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The application of user log for online business environment using content-based Image retrieval system

open access: yes, 2006
Over the past few years, inter-query learning has gained much attention in the research and development of content-based image retrieval (CBIR) systems.
Li, J.B.   +7 more
core   +1 more source

Harnessing Deep Features for Improved Multi-Query Texture Retrieval [PDF]

open access: yesEgyptian Journal of Pure and Applied Science
Developing an efficient classifier-based image retrieval system is vital for accurately and swiftly retrieving relevant images in computer vision applications.
Hewayda Lotfy
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

An image retrieval system based on explicit and implicit feedback on a tablet computer [PDF]

open access: yes, 2012
Our research aims at developing a image retrieval system which uses relevance feedback to build a hybrid search /recommendation system for images according to users’ inter ests. An image retrieval application running on a tablet computer gathers explicit
Hu, Feiyan   +2 more
core  

Matching Subsequence Music Retrieval in a Software Integration Environment

open access: yesComplexity, 2021
This paper firstly introduces the basic knowledge of music, proposes the detailed design of a music retrieval system based on the knowledge of music, and analyzes the feature extraction algorithm and matching algorithm by using the features of music ...
Zhencong Li, Qin Yao, Wanzhi Ma
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Examining and improving the effectiveness of relevance feedback for retrieval of scanned text documents [PDF]

open access: yes, 2006
Important legacy paper documents are digitized and collected in online accessible archives. This enables the preservation, sharing, and significantly the searching of these documents.
Lam-Adesina, Adenike M.   +1 more
core   +1 more source

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