Results 161 to 170 of about 383,504 (342)

EnzRetro: Enzymatic Retrosynthetic Planning With Site‐Specific Reaction Edits Based on Sequence Generative Architecture

open access: yesExploration, EarlyView.
EnzRetro bridges retrosynthesis planning and enzymatic engineering through site‐specific reaction edits. This end‐to‐end framework integrates pathway synthesis and enzyme identification into a unified process, achieving superior accuracy and enabling the efficient reconstruction of diverse biosynthetic pathways.
Yahui Cao   +5 more
wiley   +1 more source

Computer‐Aided Functional Oligosaccharide Screening and the Regulatory Role in Lipid Metabolism

open access: yesFood Bioengineering, EarlyView.
ABSTRACT This study investigated the lipid‐lowering effects and intervention mechanisms of structurally diverse functional oligosaccharides on non‐alcoholic fatty liver disease (NAFLD). By integrating computational tools such as molecular docking and molecular dynamics simulations (MDS), a comprehensive “in silico‐in vitro‐in vivo” tri‐dimensional ...
Rui Jing   +3 more
wiley   +1 more source

Multimodal Imaging in Acute Idiopathic Maculopathy: Insights from Retro-Mode Scanning Laser Ophthalmoscopy. [PDF]

open access: yesJ Vitreoretin Dis
Hande P   +5 more
europepmc   +1 more source

Nutraceutical Evaluation of Biscuits Formulated From Acha, Chia, and Soycake Flours on Glycemic Control, Lipid Profile, and Histopathological Effects in High‐Fat Diet/Streptozotocin‐Induced Type 2 Diabetic Rats

open access: yesFood Chemistry International, EarlyView.
Acha–chia–soycake biscuits improved glucose tolerance, lipid profile, insulin levels, and pancreatic integrity in HFD–STZ diabetic rats. ACSB1 and ACSB13 outperformed acarbose, showing potent antihyperglycemic, hypolipidemic, and pancreatic‐protective effects.
Oluwafunmilayo Christianah Ogunnowo   +5 more
wiley   +1 more source

Will I Regret This? Should I Care? On Regret and Wellbeing

open access: yesJournal of Applied Philosophy, EarlyView.
ABSTRACT Regret colours many areas of our lives, from the vital to the trivial. One example is in medical decision‐making, when physicians hesitate to provide procedures they think their patients will regret. For instance, physicians sometimes refuse younger women's requests for elective sterilization. Hesitating when we believe that we or someone else
Alyssa Izatt
wiley   +1 more source

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