EnzRetro bridges retrosynthesis planning and enzymatic engineering through site‐specific reaction edits. This end‐to‐end framework integrates pathway synthesis and enzyme identification into a unified process, achieving superior accuracy and enabling the efficient reconstruction of diverse biosynthetic pathways.
Yahui Cao +5 more
wiley +1 more source
Technical nuances of a posterior transdural approach for resection of a compressive retro-odontoid cyst with 2D operative video and graphical illustration: illustrative case. [PDF]
Murray TN +3 more
europepmc +1 more source
Computer‐Aided Functional Oligosaccharide Screening and the Regulatory Role in Lipid Metabolism
ABSTRACT This study investigated the lipid‐lowering effects and intervention mechanisms of structurally diverse functional oligosaccharides on non‐alcoholic fatty liver disease (NAFLD). By integrating computational tools such as molecular docking and molecular dynamics simulations (MDS), a comprehensive “in silico‐in vitro‐in vivo” tri‐dimensional ...
Rui Jing +3 more
wiley +1 more source
Multimodal Imaging in Acute Idiopathic Maculopathy: Insights from Retro-Mode Scanning Laser Ophthalmoscopy. [PDF]
Hande P +5 more
europepmc +1 more source
Acha–chia–soycake biscuits improved glucose tolerance, lipid profile, insulin levels, and pancreatic integrity in HFD–STZ diabetic rats. ACSB1 and ACSB13 outperformed acarbose, showing potent antihyperglycemic, hypolipidemic, and pancreatic‐protective effects.
Oluwafunmilayo Christianah Ogunnowo +5 more
wiley +1 more source
Inactive but Essential: The Role of the Inactive State of E49 in the Mechanism of the Alpha Subunit of Tryptophan Synthase and Its Stand-Alone Blueprint <i>Zm</i>BX1. [PDF]
Duran C, Osuna S.
europepmc +1 more source
Atlas posterior arch defect with Atlanto-occipital assimilation: Two case reports highlighting fracture mimicry and retro-odontoid pseudotumor. [PDF]
Kawanishi M +6 more
europepmc +1 more source
Will I Regret This? Should I Care? On Regret and Wellbeing
ABSTRACT Regret colours many areas of our lives, from the vital to the trivial. One example is in medical decision‐making, when physicians hesitate to provide procedures they think their patients will regret. For instance, physicians sometimes refuse younger women's requests for elective sterilization. Hesitating when we believe that we or someone else
Alyssa Izatt
wiley +1 more source
A case presenting with retro-orbital pain during endoscopic burr-hole surgery for organized chronic subdural hematoma. [PDF]
Yamada SM, Ichinose R.
europepmc +1 more source

