Results 261 to 270 of about 383,504 (342)

A Synthetic Peptide Shows Retro- and Anterograde Neuronal Transport before Disrupting the Chemosensation of Plant-Pathogenic Nematodes

, 2011
Dong Wang, Laura Jones, Peter E. Urwin, Howard J. Atkinson   +3 more
openalex   +2 more sources

Amyloid‐β aggregates induce vasculopathy via ferroptosis in brain endothelial cells

Brain Pathology, EarlyView.
Blood–brain barrier (BBB) disruption is evident in brains with amyloidopathy. In this study, we demonstrate that amyloid β (Aβ) drives abnormal lipid metabolism and lipid droplet formation in brain endothelial cells, leading to lipid peroxidation and ferroptosis.
Suhyeon Son, Suji Kim, Min‐Tae Jeon, Moonseok Choi, Kyu‐Sung Kim, Suji Lee, Seung‐Yeol Nah, Do‐Geun Kim   +7 more
wiley   +1 more source

Performance of artificial intelligence in predicting hepatocellular carcinoma recurrence after thermal ablation: A systematic review. [PDF]

World J Hepatol
Posa A, Lippi M, Barbieri P, Andreani EV, Iezzi R.   +4 more
europepmc   +1 more source

The Ins and Outs of Cholera Toxin Retro-translocation.

, 2012
Paul C. Moore
openalex   +1 more source

AAV2-Retro–Mediated Gene Transfer Selectively Targets Outer Retinal Cells Following Intravitreal Injection

Chaimaa Kinane, Moxa Panchal, Pantelis Tsoulfas, Venu Talla, Kevin K. Park   +4 more
openalex   +1 more source

Toward a Critique of Critique: Paradoxes of Byung‐Chul Han and the Dialectic of Despair and Possibility

Constellations, EarlyView.
İbrahim Berkan Karataş
wiley   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

A virtual platform for automated hybrid organic-enzymatic synthesis planning. [PDF]

Nat Commun
Wang X, Yin X, Zhang X, Zhao H, Gu S, Wu Z, Zhang O, Qian W, Huang Y, Li Y, Jiang D, Wang M, Liu H, Yao X, Hsieh CY, Hou T.   +15 more
europepmc   +1 more source

Reconsidering Instrumentality, From Mechanical Causality to Overdetermination and Political Articulation

Constellations, EarlyView.
Abdellatif Atif
wiley   +1 more source

Enhancing antitumour response to proteasome inhibitors with inhibitors of insulin‐degrading enzyme, a new molecular vulnerability in multiple myeloma

British Journal of Pharmacology, EarlyView.
Inhibitors of insulin‐degrading enzyme boost PI cytotoxicity through an increased sensitivity of proteasome to PI inhibitors, induction of ISR, DNA damage and Myc down‐regulation. They overcome PI resistance in vitro and induce tumour regression in vivo.
Laetitia Lesire, Rebecca Deprez‐Poulain, Damien Bosc, Florence Leroux, Valerie Landry, Sarah Ourabah, Morgane Tardy, Clara Maillard, Ronan Gealageas, Julie Dumont, Adrien Herledan, Sandrine Warenghem, Manon Cruette, Celine Lenglart, Alexandre Biela, Catherine Piveteau, Eva De Smedt, Catharina Muylaert, Wenguang Liang, Elvira Garcia De Paco, Elina Alaterre, Sara Ovejero, Nicolas Robert, Fabien Delahaye, Wei‐Jen Tang, Peter van Endert, Elke De Bruyne, Jérôme Moreaux, Benoit Deprez   +28 more
wiley   +1 more source