Results 71 to 80 of about 378,474 (295)

A compact high-flux cold atom beam source [PDF]

open access: yes, 2011
We report on an efficient and compact high-flux Cs atom beam source based on a retro-reflected two-dimensional magneto-optical trap (2D MOT). We realize an effective pushing field component by tilting the 2D MOT collimators towards a separate three ...
Aveline, D. C.   +5 more
core   +3 more sources

OTUD6A in Airway Epithelial Cells Exacerbates Allergic Asthma by Promoting Airway Inflammation and Airway Remodeling Through Deubiquitination of hResistin/mRELMα

open access: yesAdvanced Science, EarlyView.
This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan   +10 more
wiley   +1 more source

Ação do laser Nd:YAG sobre selamento retroapical de cavidades preparadas com ultrassom ou broca e retro-obturadas com mta ou polímero da mamona

open access: yesBrazilian Dental Science, 2011
O objetivo deste trabalho foi avaliar in vitro a ação do laser de Nd:YAG no selamento apical da dentina radicular preparada retroapicalmente com ultrassom ou broca convencional e retro-obturada com MTA ou polímero derivado do óleo da mamona.
Cláudio Antonio Talge Carvalho   +4 more
doaj   +1 more source

Small Trafficking Inhibitor Retro-2 Disrupts the Microtubule-Dependent Trafficking of Autophagic Vacuoles

open access: yesFrontiers in Cell and Developmental Biology, 2020
Autophagy is a catabolic recycling process by which a cell degrades its own constituents to contribute to cell homeostasis or survival. We report that the small trafficking inhibitor Retro-2 impairs microtubule-dependent vacuolar trafficking in autophagy.
Valérie Nicolas, Vanessa Lievin-Le Moal
doaj   +1 more source

Bell Correlations and the Common Future

open access: yes, 2017
Reichenbach's principle states that in a causal structure, correlations of classical information can stem from a common cause in the common past or a direct influence from one of the events in correlation to the other.
A Stefanov   +47 more
core   +1 more source

Neoliberalisation and 'lad cultures' in higher education [PDF]

open access: yes, 2014
This paper links HE neoliberalisation and ‘lad cultures’, drawing on interviews and focus groups with women students. We argue that retro-sexist ‘laddish’ forms of masculine competitiveness and misogyny have been reshaped by neoliberal rationalities to ...
Alison Phipps   +38 more
core   +1 more source

Genome‐Wide CRISPR Screen Reveals PIK3CA Inhibition Enhances Lipid Nanoparticle‐Mediated siRNA Delivery

open access: yesAdvanced Science, EarlyView.
A genome‐wide CRISPR screen and identifies PIK3CA as a key regulator of lipid nanoparticle (LNP) uptake is performed. Modulating PIK3CA with small‐molecule inhibitor BAY1082439 enhanced LNP uptake, siRNA delivery, and gene silencing in a variety of epithelial cells, and improved therapeutic outcomes in vivo.
Wenhan Wang, Kangfu Chen, Zongjie Wang
wiley   +1 more source

Data‐Driven Feedback Identifies Focused Ultrasound Exposure Regimens for Improved Nanotheranostic Targeting of the Brain

open access: yesAdvanced Science, EarlyView.
Machine learning models predict in real time the onset of harmful microbubble collapse during microbubble‐enhanced focused ultrasound (MB‐FUS) and enable dynamic adjustment of sonication to prevent cavitation‐induced damage. This predictive control expands the safe operating window for bloodbrain barrier opening, enhancing nanoparticle delivery and ...
Hohyun Lee   +17 more
wiley   +1 more source

Retro Design and Nostalgic Marketing: Influence of nostalgic trend in consumer behavior

open access: yesVértices, 2016
The presence of elements that refer to nostalgia in many sectors of contemporary society has been studied by researchers from various areas. In marketing, nostalgia is perceived as a market trend that attracts consumers through their past emotions.
Alline Sardinha Cordeiro Morais   +3 more
doaj   +1 more source

A Programmable Nanoreactor Orchestrates Cascade of DNA Sensing to Amplify cGAS‐STING Activation for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A programmable nanoreactor was engineered for precise cGAS‐STING pathway activation in cancer immunotherapy. This strategy bridges targeted tumor DNA damage with DC immunomodulation, providing a translatable platform to unlock innate and adaptive antitumor immunity.
Shuang Liang   +14 more
wiley   +1 more source

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