Results 161 to 170 of about 141,292 (270)

STAT3‐Mutated Hyper‐IgE Syndrome With Retroperitoneal Abscess in Adolescence

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Hyperimmunoglobulin E syndrome (HIES) is a rare primary immunodeficiency disorder characterized by eczema, recurrent staphylococcal infections, and significantly elevated serum IgE levels. An 18‐year‐old female presented with acute abdominal pain and was diagnosed with a retroperitoneal abscess.
Hiroaki Sugiyama, Yousuke Higuchi, Shintaro Fujiwara, Koki Aya, Wataru Mukai, Takafumi Goto   +5 more
wiley   +1 more source

Rare Case of Anterior Sacral Meningocele in a 30‐Year‐Old Male: Surgical Excision Using the Posterior Sagittal Approach

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Anterior sacral meningocele (ASM) is an uncommon congenital spinal abnormality in which the meningeal sac herniates through an abnormality in the anterior sacrum into the presacral space. It is more observed in females and usually asymptomatic; large ASMs may cause pressure effects on nearby pelvic structures. A 30‐year‐old male presented with
Ayesha Farooq, Zaryab Bacha, Umaima Cheema, Maryum Farooq, Abdullah Afridi, Fathimathul Henna, Muhammad Abdullah Ali, Kamil Ahmad Kamil   +7 more
wiley   +1 more source

Incidental Diagnosis of Erdheim–Chester Disease in a 42‐Year‐Old Man With Persistent Elevated ESR and Peri‐Ocular Xanthomas: A Case Report

Clinical Case Reports, Volume 14, Issue 2, February 2026.
A 42‐year‐old man with persistent ESR elevation and peri‐ocular xanthomas was diagnosed with Erdheim–Chester disease via biopsy of the accessible cutaneous lesion, supported by characteristic “hairy kidney” imaging and symmetric skeletal uptake.
Mohammad Rahimi, Alireza Ghanadan, Nooshin Shirzad, Mehrnaz Doostmohammadi, Mahboobeh Hemmatabadi   +4 more
wiley   +1 more source

Outcomes following definitive treatment of malignant peripheral nerve sheath tumor are significantly worse for patients with neurofibromatosis type 1: A Canadian Sarcoma Research and Clinical Collaboration study

Cancer, Volume 132, Issue 3, 1 February 2026.
Abstract Background Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft tissue sarcomas with a 5‐year survival rate of approximately 50%, secondary to their metastatic potential and resistance to therapy. MPNSTs can arise sporadically, as a late toxicity from therapeutic radiotherapy, or in patients with neurofibromatosis type 1 (NF1).
Rachel E. Aubrey, Pamela Psarianos, Anna T. Santiago, Anthony M. Griffin, Peter C. Ferguson, Abha A. Gupta, Hagit Peretz Soroka, David B. Shultz   +7 more
wiley   +1 more source

A case of retroperitoneal giant leiomyoma and literature review. [PDF]

Ther Adv Urol
Lai Z, Shi X, Wang Q, Lalani S, Wang Y, Lian Y, Zheng Z, Huang W, Pang S, Tan W.   +9 more
europepmc   +1 more source

TIMP2 promotes AKI‐CKD transition by inducing tubular maladaptive repair and cell senescence via targeting Wnt/β‐catenin signalling

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
1. TIMP2 is upregulated in injured renal tubules and promotes maladaptive repair and cell senescence. 2. Genetic deletion of TIMP2 in tubular epithelial cells attenuates renal fibrosis and improves mitochondrial function. 3. TIMP2 activates Wnt/β‐catenin signalling by binding to LRP6 via an MMP‐independent mechanism.
Dongxue Xu, Haichuan Yu, Jingjing Pang, Xiaoyu Zhang, Jun Jiang, Yiming Li, Zhiyong Peng   +6 more
wiley   +1 more source

Total laparoscopic excision of pelvic retroperitoneal ganglioneuroma: a case report and review of the literature. [PDF]

Front Surg
Lan K, Ding H, Liu W, Tang H, Chen G, Huang P.   +5 more
europepmc   +1 more source

Ellagic Acid Alleviates Abnormal Fat Reduction by Activating the RXRβ–PPARγ Pathways in a CT26 Tumour‐Induced Cachexia Mouse Model

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Cancer cachexia is a syndrome characterized by significant weight loss, particularly of adipose tissue, which negatively impacts patient survival. Pharmacological approaches to prevent this abnormal fat reduction remain poorly defined.
Woo Yong Park, Beomsu Kim, Gahee Song, Sang Hee Kim, Jin‐Hyung Kim, Ja Yeon Park, Se Jin Jung, Wenjun Jiao, Jisoo Han, Taekyoung Kong, Kwang Seok Ahn, Hyun Jeong Kwak, Jae‐Young Um   +12 more
wiley   +1 more source

A rare case of deep fibrous histiocytoma with low-grade myxoid and dedifferentiated liposarcoma features: clinical, radiological, and histopathological insights. [PDF]

J Surg Case Rep
Verbo A, Bez MA, Di Giorgio D, Verbo I.
europepmc   +1 more source

Validation of preoperative variables and stratification of patients to help predict benefit of cytoreductive nephrectomy in the targeted therapy ERA [PDF]

, 2017
Kim, Eric H, Manley, Brandon J, Potretzke, Aaron M, Strope, Seth A, Vetter, Joel M   +4 more
core   +2 more sources