Results 151 to 160 of about 717,270 (306)

Comparison of Direct Oral Anticoagulants for Treatment of Cerebral Venous Thrombosis – A Retrospective Cohort Study

open access: yesClinical and Applied Thrombosis/Hemostasis
Limited available evidence comparing DOACs with warfarin suggests efficacy and safety of DOACs for CVT. We aimed to evaluate whether a specific DOAC is preferred for the treatment of CVT. This retrospective cohort study included adult patients with CVTs between September 2018 and September 2022 treated with a DOAC.
Paul Phan, Lisa T. Hong
openaire   +3 more sources

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz   +9 more
wiley   +1 more source

Establishment and validation of a clinical threshold criteria for choosing PET imaging tracers for indolent non-Hodgkin’s lymphoma

open access: yesEJNMMI Research
Background [18F]FDG PET-CT scan has a lower sensitivity in imaging of indolent non-Hodgkin’s Lymphoma (NHL.) We aimed at identifying a threshold of clinical/pathological indicators which would independently predict [18F]FDG PET-CT scan positivity.
Xuebing Yu   +7 more
doaj   +1 more source

Reperfusion‐Dependent Outcomes After Endovascular Thrombectomy Stratified by NIHSS‐ASPECTS Clinical‐Core Mismatch

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht   +53 more
wiley   +1 more source

Comparison of four ventilation tubes commonly used in the pediatric population: A retrospective cohort study

open access: yesLaryngoscope Investigative Otolaryngology
AbstractObjectiveTo assess differences in otorrhea, tympanic membrane perforation, and time to extrusion in children receiving one of four commonly used, short‐term ventilation tubes for the first time.MethodsRetrospective chart review of 2 years of postoperative follow‐up to analyze patient outcomes after insertion of either a Paparella type‐I ...
Margareta Morrissette   +4 more
openaire   +3 more sources

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

Primary medullary adenocarcinoma of the colon: Literature review and case series

open access: yesSurgery in Practice and Science
Aims: Medullary carcinoma of the colon is a rare subtype of adenocarcinoma, first described in 1999. Clinically known to have a favourable prognosis in comparison to poorly differentiated cancers, it is associated with deficient mismatch repair.
Hein Maung   +8 more
doaj   +1 more source

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi   +8 more
wiley   +1 more source

Comparison between open and laparoscopic surgery for liver hydatid cyst: a retrospective cohort study

open access: yesEgyptian Liver Journal
Background Comparative evidence on laparoscopic versus open surgery for hepatic hydatid-cyst disease in endemic regions remains limited. Methods We reviewed records of 43 consecutive patients who underwent surgery for liver hydatid cysts at two tertiary ...
Ali Rahnamei   +6 more
doaj   +1 more source

Clinical outcome after first and recurrent hemorrhage in patients with untreated brain arteriovenous malformation [PDF]

open access: yes, 2006
Background and Purpose: The morbidity from spontaneous hemorrhage of untreated brain arteriovenous malformations (AVM) is not well described. Methods: The 241 consecutive AVM patients (mean age 3716 years, 52% women) from the prospective Columbia AVM ...

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