Results 141 to 150 of about 3,326,214 (390)

Evaluation of personalized cancer therapies based on comprehensive genomic profiling in a middle-sized oncologic center in Austria, the University Clinic Krems

Translational Oncology, 2021
Background and Aim: To successfully apply personalized cancer therapies, thorough understanding of the patient's tumor is needed. In-depth, comprehensive genomic profiling systems allow gathering this knowledge by testing hundreds of cancer-related genes.
Josef Singer, Elias Brauneck, Elisabeth Zwickl-Traxler, Martin Pecherstorfer   +3 more
doaj  

Clinical Impact of Metagenomic Next-Generation Sequencing of Plasma Cell-Free DNA for the Diagnosis of Infectious Diseases: A Multicenter Retrospective Cohort Study

medRxiv, 2019
Background: Metagenomic next-generation sequencing (mNGS) of plasma cell-free DNA has emerged as an attractive diagnostic modality allowing broad-range pathogen detection, noninvasive sampling, and earlier diagnosis.
C. Hogan, Shangxin Yang, O. Garner, D. Green, C. Gomez, J. Dien Bard, B. Pinsky, N. Banaei   +7 more
semanticscholar   +1 more source

Which asthma patients should get the pneumococcal vaccine? [PDF]

, 2009
Adults between the ages of 19 and 64 years who have chronic lung disease, including asthma, should get the vaccine, as should all patients 65 years and older (strength of recommendation [SOR]: C, consensus guide-lines).
Edgerton, Lisa, Harris, John Brock, Stafford, Karen   +2 more
core  

Prenatal Exposure to Tetrachloroethylene-Contaminated Drinking Water and the Risk of Congenital Anomalies: A Retrospective Cohort Study [PDF]

, 2009
BACKGROUND: Prior animal and human studies of prenatal exposure to solvents including tetrachloroethylene (PCE) have shown increases in the risk of certain congenital anomalies among exposed offspring. OBJECTIVES: This retrospective cohort study examined
Aschengrau, Ann, Gallagher, Lisa G., Janulewicz, Patricia A., Ozonoff, David M., Vieira, Veronica M., Webster, Thomas F., Weinberg, Janice M., Winter, Michael R.   +7 more
core   +3 more sources

Genetic Profile and Symptom Pattern Explain Variability of Deep Brain Stimulation Effect in Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Bilateral globus pallidus pars interna deep brain stimulation (GPi‐DBS) is a recognized and effective treatment option for drug‐resistant dystonia patients. However, the clinical GPi‐DBS outcomes vary significantly. Herein, we explored the pre‐implant factors affecting GPi‐DBS effectiveness.
Mahboubeh Ahmadipour, Luigi M. Romito, Antonio E. Elia, Nico Golfré Andreasi, Roberto Eleopra, Alberto Mazzoni, Fabiana Colucci   +6 more
wiley   +1 more source

Surgical management of glenohumeral instability in patients with Ehlers-Danlos syndrome/hypermobility spectrum disorder and their risk of reoperation

JSES Reviews, Reports, and Techniques
Background: This study aims to characterize the types of procedures performed on patients previously diagnosed with Ehlers-Danlos syndrome (EDS)/hypermobility spectrum disorder (HSD) and investigate rates of revision surgery following open, arthroscopic,
Julia M. Winschel, MPH, J. Alex Albright, BS, Edward J. Testa, MD, Victoria F. Kent, BS, Rory A. Byrne, BA, Elaine W. He, BA, Alan H. Daniels, MD, Brett D. Owens, MD   +7 more
doaj  

Association between triglyceride-glucose index and hypertension: a cohort study based on the China Health and Nutrition Survey (2009–2015)

BMC Cardiovascular Disorders
Aim Insulin resistance (IR) may participate in the pathogenesis of hypertension by mediating low-grade systemic inflammation. The triglycerides-glucose (TyG) index has recently been suggested as a reliable alternative biochemical marker of IR compared ...
Su Wang, Qian Wang, Xianliang Yan
doaj   +1 more source

The effect of age on referral to and use of specialist palliative care services in adult cancer patients: a systematic review [PDF]

, 2006
Objective: to investigate variations in the use of specialist palliative care (SPC) services for adult cancer patients, in relation to age.Design: systematic review of studies examining use of or referral to SPC services in adult cancer patients.Search ...
Burt, J, Raine, R
core   +1 more source

Relevance of Kappa and Lambda Free Light Chains in Autoimmune Astrocytopathy Associated With Anti‐GFAP Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction The kappa‐free light chain (κ‐FLC) index is known to be highly sensitive and specific for diagnosing multiple sclerosis (MS), while little is understood about lambda (λ)‐FLC. This study assessed the κ‐FLC and λ‐FLC indices in autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy.
Michael Levraut, Romain Marignier, Mikael Cohen, Jeanne Benoit, Cassandre Landes‐Chateau, Elisabeth Maillart, Marion Cremoni, Barbara Seitz‐Polski, Anne‐Laurie Pinto, Pauline Dumez, Jérôme Honnorat, Christine Lebrun‐Frenay   +11 more
wiley   +1 more source

Nonadherence of Polyurethane Implants: A Retrospective Cohort Study

Indian Journal of Plastic Surgery
Abstract Background Biointegration of polyurethane (PU) implants providing their stable position years after surgery ensures predictable results of breast augmentation and reconstruction almost eliminating implant factor as a cause of complications. However, in rare cases PU implants appear to be not connected to the surrounding tissues.
Dmitry Batiukov, Vladimir Podgaiski
openaire   +3 more sources