Results 171 to 180 of about 3,326,214 (390)
Understanding Mechanisms of Whole Brain and Regional Grey Matter Atrophy in Children With MOGAD
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
To investigate the mechanisms driving whole brain and regional grey matter (GM) volume changes along with their clinical correlates in paediatric myelin oligodendrocyte glycoprotein antibody (MOG‐Ab)–associated disease (MOGAD). Methods
One‐hundred‐nine paediatric MOGAD patients from two UK centres underwent MRI at attack nadir and ...Ermelinda De Meo, Riccardo Nistri, Michael Eyre, Cheryl Hemingway, Ming Lim, Thomas Rossor, Asthik Biswas, Kshitij Mankad, Ata Siddiqui, Sniya Sudhakar, Declan Chard, Frederik Barkhof, Arman Eshaghi, Olga Ciccarelli, Yael Hacohen +14 morewiley +1 more sourceRegional trends in perceptions of American Shoulder and Elbow Surgeons towards barriers to access for patients with Medicaid: limited perioperative service access, low patient engagement, and decreased reimbursement are regionally consistent obstacles
JSES Reviews, Reports, and TechniquesBackground: Medicaid is a means-tested health insurance program for low-income adults (∼30%), children (∼40%), individuals with disabilities (15%) and some elderly patients that are dual Medicare and Medicaid eligible (15%).Patrick Saunders, MD, Abhay Mathur, MD, Jordan Frausto, BA, Carlos D. Ramirez, BS, Adam Z. Khan, MD, Brad Bushnell, MD, Hafiz F. Kassam, MD +6 moredoaj High‐Efficacy Treatment in Neuromyelitis Optica Specturm Disorder Patients With Seropositive AQP4 Antibodies—A Real‐World Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
To compare the effectiveness of high‐efficacy treatments (HET) and low‐efficacy treatments (LET) in NMOSD patients with anti‐aquaporin‐4 antibodies (AQP4‐ab). Methods
In this multi‐center study, we analyzed 183 AQP4‐ab seropositive NMOSD patients who received immunosuppressive treatments (IST).Xiang Li, Binbin Xue, Jia Li, Dewei Xie, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Xu Zhang, Junhui Xia, Jie Lin +10 morewiley +1 more sourceReal‐World Comparison of High‐Efficacy Versus Non‐High‐Efficacy Therapies in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
The choice of the first disease modifying treatment (DMT) in multiple sclerosis (MS) is a topic of great interest, and whether high‐efficacy DMTs should be the first choice remains debated. We compared treatment outcomes (no evidence of disease activity [NEDA] and its components) between treatment‐naïve relapsing–remitting MS (RRMS ...Sarmad Al‐Araji, Marcello Moccia, Alessia Bianchi, Charmaine Yam, Weaam Hamed, Suraya Mohamud, Alan J. Thompson, Frederik Barkhof, Ahmed T. Toosy, Olga Ciccarelli +9 morewiley +1 more sourceWorldwide experience of homozygous familial hypercholesterolaemia: retrospective cohort study
The Lancet, 2022 T. Tromp, M. Hartgers, G. Hovingh, A. Vallejo-Vaz, K. Ray, H. Soran, T. Freiberger, S. Bertolini, M. Harada‐Shiba, D. Blom, F. Raal, M. Cuchel, T. Tromp, M. Hartgers, G. Hovingh, A. Vallejo-Vaz, K. Ray, S. Bertolini, J. Pang, G. Watts, S. Greber-Platzer, M. Mäser, T. Stulnig, C. Ebenbichler, Khalid Bin Thani, D. Cassiman, O. Descamps, D. Rymen, P. Witters, R. Santos, L. Brunham, G. Francis, J. Genest, R. Hegele, Brooke A. Kennedy, I. Ruel, M. Sherman, Long Jiang, Luya Wang, Ž. Reiner, V. Bláha, R. Češka, J. Dvořáková, Lubomir Dlouhy, P. Horák, V. Soška, L. Tichý, R. Urbánek, H. Vaverkova, M. Vrablík, S. Zemek, L. Zlatohlávek, S. Emil, T. Naguib, A. Reda, S. Béliard, E. Bruckert, A. Gallo, M. Elisaf, G. Kolovou, H. Cohen, R. Durst, E. Dann, A. Elis, O. Hussein, E. Leitersdorf, D. Schurr, N. Setia, I. Verma, Mohammed Alareedh, M. Al-Khnifsawi, A. F. Al-Zamili, S. H. Rhadi, Foaad K. Shaghee, M. Arca, M. Averna, A. Bartuli, M. Bucci, P. Buonuomo, P. Calabrò, S. Calandra, M. Casula, A. Catapano, A. Cefalù, A. Cicero, S. D’Addato, L. D’Erasmo, A. D. Costanzo, T. Fasano, M. Gazzotti, A. Giammanco, G. Iannuzzo, A. Ibba, E. Negri, A. Pasta, C. Pavanello, L. Pisciotta, C. Rabacchi, Carlo Ripoli, T. Sampietro, F. Sbrana, F. Sileo, P. Suppressa, P. Tarugi, C. Trenti, M. Zenti, M. Hori, M. Ayesh, S. Azar, F. Bitar, A. Fahed, E. Moubarak, G. Nemer, H. Nawawi, R. Madriz, R. Mehta, A. Cupido, J. Defesche, M. Reijman, J. R. Lennep, E. Stroes, A. Wiegman, L. Zuurbier, K. Al-Waili, F. Sadiq, K. Chlebus, M. Bourbon, I. Gaspar, K. Lalić, M. Ezhov, A. Susekov, U. Grošelj, M. Charng, W. Khovidhunkit, M. Aktan, B. Altunkeser, Sinan Demircioğlu, M. Kose, C. Gokce, O. Ilhan, M. Kayıkçıoğlu, L. Kaynar, I. Kuku, E. Kurtoğlu, H. Okutan, O. Ozcebe, Z. Pekkolay, S. Sag, O. Salcioglu, A. Temizhan, M. Yenerçağ, M. Yilmaz, H. Y. Yasar, O. Mitchenko, A. Lyons, C. Stevens, J. Brothers, L. Hudgins, C. Nguyen, R. Alieva, A. Shek, D. Do, N. Kim, H. Le, T. Le, M. Nguyen, T. Truong, D. Blom, F. Raal +168 moresemanticscholar +1 more sourceEarly Intensive Versus Escalation Approach: Ten‐Year Impact on Disability in Relapsing Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
To evaluate the long‐term impact of early intensive treatment (EIT) versus escalation (ESC) strategies using high‐efficacy disease‐modifying therapies (HE‐DMTs) on disability progression in relapsing multiple sclerosis (RMS). Methods
This observational study included 4878 RMS patients from the Italian Multiple Sclerosis Register ...Pietro Iaffaldano, Giuseppe Lucisano, Tommaso Guerra, Francesca Caputo, Marta Simone, Massimiliano Copetti, Damiano Paolicelli, Emilio Portaccio, Francesco Patti, Paola Perini, Vincenzo Brescia Morra, Alessia Di Sapio, Matilde Inglese, Carlo Pozzilli, Giacomo Lus, Giuseppe Salemi, Erica Curti, Giovanna De Luca, Paola Valentino, Eleonora Cocco, Paola Cavalla, Carlo Avolio, Alessandra Lugaresi, Antonio Gallo, Pietro Annovazzi, Maria A. Rocca, Clara Grazia Chisari, Massimo Filippi, Maria Pia Amato, Maria Trojano, on behalf of the Italian MS Register, Beatrice Biolzi, Daniele Dell’Anna, Daniele Di Giulio Cesare, Sonia Di Lemme, Chiara Di Tillio, Teresa Fonsdituri, Ilaria Maietta, Agata Marchese, Silvia Marinetto, Federica Martini, Cristiana Morano, Silvia Perugini, Giovanna Ramona Piredda, Chiara Raimondi, Ilaria Rossi, Valentina Tallarico, Stefania Treccarichi +47 morewiley +1 more sourceAssociation of the ICH Score With Withdrawal of Life‐Sustaining Treatment Over a 10‐Year Period
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective
The intracerebral hemorrhage (ICH) score was developed to enhance provider communication and facilitate early severity assessment. We examined the association of the ICH score with mortality and withdrawal of life‐sustaining treatment (WLST) in a large, multicenter stroke registry, and evaluated temporal trends in these associations. Nina Massad, Lili Zhou, Brian Manolovitz, Negar Asdaghi, Hannah Gardener, Hao Ying, Carolina M. Gutierrez, Angus Jameson, David Rose, Mohan Kottapally, Amedeo Merenda, Kristine O'Phelan, Sebastian Koch, Jose G. Romano, Tatjana Rundek, Ayham Alkhachroum +15 morewiley +1 more source