Results 171 to 180 of about 70,872 (219)

Distinct Systemic Sclerosis Phenotypes Related to Ethnicity: An Opportunity to Personalize Care?

Arthritis Care &Research, EarlyView.
Objective The objective is to describe and compare demographic, clinical, and serological characteristics of patients with systemic sclerosis (SSc) according to ethnic background. Methods Participants enrolled in the Canadian Scleroderma Research Group cohort who self‐identified to a single ethnicity group were included.
Danick Goulet, Camille Guertin, Maggie Larché, Isabelle Ferdinand, Marie Hudson, May Y. Choi, Mohammed Osman, Janet Pope, Carter Thorne, Murray Baron, Sasha Bernatsky, Sabrina Hoa   +11 more
wiley   +1 more source

Real‐World Safety and Effectiveness of JAK Inhibitors in Systemic Sclerosis: A Propensity‐Matched Study From the EUSTAR Cohort

Arthritis Care &Research, EarlyView.
Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato, Marie‐Elise Truchetet, Marco Minerba, Oliver Distler, Juan José Alegre Sancho, Yolanda Braun‐Moscovici, Christina Bergmann, Petros Sfikakis, Jeska K. de Vries‐Bouwstra, Murray Baron, Silvia Bellando‐Randone, Lorenzo Dagna, Christopher P. Denton, Madelon C. Vonk, Vanessa Smith, Ivan Castellvi, Gabriela Riemekasten, Andra Balanescu, Masataka Kuwana, Maria De Santis, Kamal Solanki, Anastas Batalov, Vahan Mukuchyan, Marco Matucci‐Cerinic, Yannick Allanore, Francesco Del Galdo, Michael Hughes, EUSTAR Collaborators   +27 more
wiley   +1 more source

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki, Alireza Amindarolzarbi, Tsion Abdi, John Clarke, Michael Hughes, Ami A. Shah, Zsuzsanna H. McMahan   +6 more
wiley   +1 more source

Association of Elevated Platelets and C‐Reactive Protein With Severe Disease and Poor Survival in Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective Elevated C‐reactive protein (CRP) levels in systemic sclerosis (SSc) have been linked with severe disease and worse survival, but the role of platelet levels remains unclear. This study examined whether elevated platelet levels, CRP levels, or both are associated with disease severity, progression, and survival in SSc.
Brian S. Lee, Shufeng Li, Srijana Davuluri, Jennifer Lee, Lorinda Chung   +4 more
wiley   +1 more source

Short‐term response to biologic therapy in psoriatic arthritis (PsA) is not influenced by disease duration at initiation of therapy

Arthritis Care &Research, Accepted Article.
Objectives We aimed to determine whether the short‐term response to biologics in biologic‐naïve psoriatic arthritis (PsA) is better in patients initiating biologic treatment early in the disease course. Methods PsA patients who started biologic therapy from the year 2000 to 2025 were included for analysis. Patients considered in the early treatment (ET)
Sung Min Cho, Shangyi Gao, Daniel Pereira, Richard J. Cook, Dafna D. Gladman   +4 more
wiley   +1 more source

Renal Impairment in Wilson’s Disease

Kidney International Reports
Zi-Wei Zheng, Meng-Hui Xu, Lu-Na Fan, Rou-Min Wang, Wan-Qing Xu, Guo-Min Yang, Ling-Yu Guo, Chuan Liu, Yi Dong, Zhi-Ying Wu   +9 more
doaj   +1 more source

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Diabetes and Burns: Retrospective Cohort Study

The Journal of Burn Care & Rehabilitation, 2001
Abstract Burn injuries are often associated with multisystemic complications, even in otherwise healthy individuals. It is therefore intuitive that for the diabetic patient, the underlying pathophysiologic alterations in vascular supply, peripheral neuropathy, and immune function could have a profoundly devastating impact on patient ...
Beth, McCampbell, Nabil, Wasif, Angela, Rabbitts, Lisa, Staiano-Coico, Roger W, Yurt, Suzanne, Schwartz   +5 more
openaire   +2 more sources

Osteosynthesis of scapular fractures: a retrospective cohort study

Archives of Orthopaedic and Trauma Surgery, 2022
In recent years a trend from conservative to operative treatment of displaced scapula fractures has evolved. The aim of this study was to assess surgical and patient-based radiological and functional outcome after open reduction and internal fixation (ORIF) of displaced scapula fractures following predefined operative indications.We retrospectively ...
Christian Michelitsch, Nina Kabelitz, Herman Frima, Method Kabelitz, Reinier Beks, Philipp F. Stillhard, Christoph Sommer   +6 more
openaire   +2 more sources

Multiple sclerosis in the elderly: a retrospective cohort study

Journal of Neurology, 2023
There is a lack of knowledge of disease course, prognosis, comorbidities and potential treatments of elderly MS patients.To characterize the disease course including disability progression and relapses, to quantify the use of DMTs and to identify comorbidities and risk factors for progression in elderly multiple sclerosis (MS) patients.This is a ...
Anne Zinganell, Georg Göbel, Klaus Berek, Barbara Hofer, Susanne Asenbaum-Nan, Matin Barang, Klaus Böck, Christian Bsteh, Gabriel Bsteh, Stephan Eger, Christian Eggers, Elisabeth Fertl, Damir Joldic, Michael Khalil, Dieter Langenscheidt, Martina Komposch, Barbara Kornek, Jörg Kraus, Reinhard Krendl, Helmut Rauschka, Johann Sellner, Michael Auer, Harald Hegen, Franziska Di Pauli, Florian Deisenhammer   +24 more
openaire   +2 more sources

Assessing the Feasibility of Retrospective Cohort Studies

American Journal of Industrial Medicine, 1987
AbstractWhile most epidemiologic cohort studies are preceded by some sort of feasibility study, details of such prior investigations are rarely reported. Yet it is during such feasibility studies that critical decisions are made, such as site selection and definition of exposure.
K, Steenland, L, Stayner, A, Greife
openaire   +2 more sources