Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis
One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen+3 more
wiley +1 more source
Background: Between February and June 2021, the initial wild-type strains of SARS-CoV-2 were supplanted in Ontario, Canada, by new variants of concern (VOCs), first those with the N501Y mutation (i.e., Alpha/B1.1.17, Beta/B.1.351 and Gamma/P.1 variants ...
D. Fisman, A. Tuite
semanticscholar +1 more source
Factors modulating 99mTc‐MAA planar lung dosimetry for 90Y radioembolization
Abstract Purpose To investigate the accuracy and biases of predicted lung shunt fraction (LSF) and lung dose (LD) calculations via 99mTc‐macro‐aggregated albumin (99mTc‐MAA) planar imaging for treatment planning of 90Y‐microsphere radioembolization.
Benjamin P. Lopez+4 more
wiley +1 more source
Real-world effectiveness of steroids in severe COVID-19: a retrospective cohort study
Introduction Randomised controlled trials have shown that steroids reduce the risk of dying in patients with severe Coronavirus disease 2019 (COVID-19), whilst many real-world studies have failed to replicate this result. We aim to investigate real-world
Wenjuan Wang+8 more
doaj +1 more source
Uniqueness of radiomic features in non‐small cell lung cancer
Abstract Purpose The uniqueness of radiomic features, combined with their reproducibility, determines the reliability of radiomic studies. This study is to test the hypothesis that radiomic features extracted from a defined region of interest (ROI) are unique to the underlying structure (e.g., tumor). Approach Two cohorts of non‐small cell lung cancer (
Gary Ge, Jie Zhang
wiley +1 more source
Long COVID following Omicron wave in Eastern India—A retrospective cohort study
Long coronavirus disease (COVID) or postacute sequelae of coronavirus disease of 2019 (COVID‐19) is widely reported but the data of long COVID after infection with the Omicron variant is limited.
A. C.+12 more
semanticscholar +1 more source
Causal effect of chemotherapy received dose intensity on survival outcome: a retrospective study in osteosarcoma [PDF]
This study aims to analyse the effects of reducing Received Dose Intensity (RDI) in chemotherapy treatment for osteosarcoma patients on their survival by using a novel approach. In this scenario, toxic side effects are risk factors for mortality and predictors of future exposure levels, introducing post-assignment confounding.
arxiv +1 more source
Development and validation of an interpretable machine learning-based calculator for predicting 5-year weight trajectories after bariatric surgery: a multinational retrospective cohort SOPHIA study [PDF]
Background Weight loss trajectories after bariatric surgery vary widely between individuals, and predicting weight loss before the operation remains challenging. We aimed to develop a model using machine learning to provide individual preoperative prediction of 5-year weight loss trajectories after surgery.
arxiv +1 more source
Patient Satisfaction With Telemedicine During the COVID-19 Pandemic: Retrospective Cohort Study
Background New York City was the international epicenter of the COVID-19 pandemic. Health care providers responded by rapidly transitioning from in-person to video consultations.
Ashwin Ramaswamy+6 more
semanticscholar +1 more source
There have been limited data assessing the influence of disadvantaged socioeconomic status (SES) on the incidence and clinical outcomes of COVID-19 patients within the diverse communities of the United States.
Christine Little+8 more
semanticscholar +1 more source