Results 231 to 240 of about 1,336,811 (364)

Use of Thiazolidinediones and Risk of Heart Failure in People With Type 2 Diabetes: A Retrospective Cohort Study: Response to Karter et al. [PDF]

, 2004
Thomas E. Delea, John Edelsberg, May Hagiwara, Gerry Oster, Lawrence S. Phillips   +4 more
openalex   +1 more source

Spatial Transcriptomics Reveals Transcriptomic and Immune Microenvironment Reprogramming during Thyroid Carcinoma Dedifferentiation

Advanced Science, EarlyView.
Spatial transcriptomic analysis of Anaplastic thyroid carcinoma (ATC)‐differentiated thyroid carcinoma (DTC) coexisting tumors reveals that coexisting DTC regions with ATC‐like genomic alterations undergo sequential transcriptomic reprogramming and immune microenvironment remodeling, ultimately evolving into a full ATC pathological phenotype.
Kang Ning, Bu Zou, Yongchao Yu, Taonong Cai, Zhenyu Luo, Yu Guo, Yi Wu, Xiujiao Shen, Hao Li, Mengyuan Fang, Jian Bu, Han Hong, Zan Jiao, Tong Wu, Yulong Wang, Tianrun Liu, Weichao Chen, Wanming Hu, Mingjie Jiang, Ankui Yang   +19 more
wiley   +1 more source

Perinatal antibiotic exposure and risk of childhood infections: a retrospective cohort study. [PDF]

Lancet Reg Health Am
Coggins SA, Quarshie W, Grundmeier RW, Shu D, Gerber JS, Dhudasia MB, Puopolo KM, Mukhopadhyay S.   +7 more
europepmc   +1 more source

Homocysteine Exacerbates Pulmonary Fibrosis via Orchestrating Syntaxin 17 Homocysteinylation of Alveolar Type II Cells

Advanced Science, EarlyView.
The study identifies elevated homocysteine (Hcy) levels in idiopathic pulmonary fibrosis patients' samples, with alveolar type 2 cells as the primary site of Hcy metabolism. Methionine synthase reductase downregulation in these cells exacerbates fibrosis, while folate administration reduces Hcy levels and alleviates fibrosis.
Jiefeng Huang, Ke Fang, Wuyan Lu, Rongrong Wu, Yuanyuan Chen, Linxiao Li, Zihao Hu, Zixin Cai, Yu Jiang, Xinli Fan, Jinyi Deng, Guangpeng Liu, Zhuang Luo, Lei Cui, Shuaijun Li   +14 more
wiley   +1 more source

A Retrospective Cohort Study of Leptospirosis in Crete, Greece. [PDF]

Trop Med Infect Dis
Ioannou P, Pendondgis M, Kampanieri E, Koukias S, Gorgomyti M, Tryfinopoulou K, Kofteridis D.   +6 more
europepmc   +1 more source

Increased treatment failure after 3‐days’ courses of nitrofurantoin and trimethoprim for urinary tract infections in women: a population‐based retrospective cohort study using the PHARMO database [PDF]

, 2004
Wim Goettsch, R. Janknegt, Ron M. C. Herings   +2 more
openalex   +1 more source

Targeting ROCK2 to Restore Epileptic Synaptic Networks via Mitophagy Activation: Insights from Translational Imaging of SV2A In Vivo

Advanced Science, EarlyView.
By integrating synaptic vesicle glycoprotein 2A PET imaging and transcriptomics, this study identifies Rho‐associated protein kinase 2 (ROCK2) as a critical regulator of synaptic network dysfunction in temporal lobe epilepsy. Pharmacological ROCK2 inhibition restores synaptic density and enhances mitophagy, thereby reducing seizures and neuronal damage.
Ling Xiao, Jing Wang, Bei Chen, Jinhui Yang, Fangyu Wu, Chunyao Zhou, Yifei Zhang, Zhiquan Yang, Dingyang Liu, Lei Tian, Jianhua Yu, Fei Han, Yongxiang Tang, Li Feng, Shuo Hu   +14 more
wiley   +1 more source

Epidemiology of prehospital traumatic cardiac arrest in Geneva: a retrospective cohort study. [PDF]

Scand J Trauma Resusc Emerg Med
Midez R, Suppan L, Egger C, Jourdan E, Quintard H, de Valence T.   +5 more
europepmc   +1 more source

Helicobacter pyloriinfection and gastric cancer: evidence from a retrospective cohort study and nested case-control study in China

, 2002
Run-Tian Wang
openalex   +1 more source

Pregnancy Complications and Subsequent Maternal Cerebrovascular Events: A Retrospective Cohort Study of 119,668 Births [PDF]

, 2004
Jill P. Pell
openalex   +1 more source