Results 261 to 270 of about 3,326,214 (390)

An Explainable Multimodal Artificial Intelligence Model Integrating Histopathological Microenvironment and EHR Phenotypes for Germline Genetic Testing in Breast Cancer

Advanced Science, EarlyView.
This study presents an explainable multimodal AI model, MAIGGT (Multimodal Artificial Intelligence Germline Genetic Testing), that combines whole‐slide histopathology with clinical data for accurate germline BRCA1/2 mutation prescreening. By integrating digital pathology and EHR phenotypes, MAIGCT enables cost‐effective, scalable hereditary breast ...
Zijian Yang, Changyuan Guo, Jiayi Li, Yalun Li, Lei Zhong, Pengming Pu, Tongxuan Shang, Lin Cong, Yongxin Zhou, Guangdong Qiao, Ziqi Jia, Hengyi Xu, Heng Cao, Yansong Huang, Tianyi Liu, Jian Liang, Jiang Wu, Dongxu Ma, Yuchen Liu, Ruijie Zhou, Xiang Wang, Jianming Ying, Meng Zhou, Jiaqi Liu   +23 more
wiley   +1 more source

Surgical and Conservative Management in Otitic Barotrauma: A Retrospective Cohort Study. [PDF]

OTO Open
Khan FI, Vazquez SG, Vannier AGL, Dongre R, Ahmed OG, Imbery TE, Vrabec JT.   +6 more
europepmc   +1 more source

383 Pregnancies before and after diagnosis of systemic lupus erythematosus: A retrospective cohort study

, 2001
J. Patricia Dhar, Lynnette Essenmacher, Joel W. Ager, Robert J. Sokol   +3 more
openalex   +1 more source

Spontaneous loss of early pregnancy and risk of ischaemic heart disease in later life: retrospective cohort study [PDF]

, 2003
Gordon C. S. Smith
openalex   +1 more source

HLA‐DR⁺ Tumor Cells Show an Association with a Distinct Immune Microenvironment and CD8⁺ T‐Cell Exhaustion in HBV‐Associated Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study integrates scRNA‐seq, multiplex immunofluorescence, and clinical data to identify HLA‐DR⁺tumor cells uniquely enriched in Hepatocellular carcinoma (HCC) with hepatitis B virus (HBV). These cells express MHC II, associate with PD‐L1, recruit and exhaust CD8⁺T cells, predict poor survival, and serve as potential biomarkers for immunotherapy ...
Jun‐Qing Chang, Yan Guo, Wen‐Jing Yuan, Yu‐Man Chen, Bo‐Wei Liu, Wen‐Tao Li, Xiang‐Ming Ding, Xu‐Dong Fu, Yu‐Han Lou, Zhuo‐Ran Chen, Xiao‐Ying Luo, Song‐Ze Ding, Bing‐Yong Zhang, Xiu‐Ling Li, Yong‐Zhi Hong, Shun‐Dong Cang, Dong‐Xiao Li, Ling Lan   +17 more
wiley   +1 more source

Dyskalaemia as a predictor of mortality in sepsis: a retrospective cohort study. [PDF]

BMC Infect Dis
Süzer NE, Özel M.
europepmc   +1 more source

Retrospective cohort study examining incidence of HIV and hepatitis C infection among injecting drug users in Dublin [PDF]

, 2003
Bobby P. Smyth
openalex   +1 more source

Identification and Drug Screening of Single Cells from Human Tumors on Semiconductor Chip for Cancer Precision Medicine

Advanced Science, Volume 12, Issue 28, July 24, 2025.
The study innovatively integrates single‐cell electric impedance identification and drug screening on a semiconductor chip, addressing tumor heterogeneity limitations. The system achieves label‐free cancer cell recognition while concurrently evaluating drug efficacy on cancer cells and toxicity on noncancerous cells.
Wenhao Hui, Ka‐Meng Lei, Yingying Liu, Xinru Huang, Yunlong Zhong, Xiaojun Chen, Mingji Wei, Jie Yan, Ren Shen, Pui‐In Mak, Rui P. Martins, Shuhong Yi, Ping Wang, Yanwei Jia   +13 more
wiley   +1 more source

Dual-targeted therapy for the management of refractory Crohn's disease: a retrospective cohort study. [PDF]

Clin Exp Med
He J, Zhang J, Zhou H, Da Y, Liu X, Zhang T, Fan Z, Wu T, Shi Y, Liang J.   +9 more
europepmc   +1 more source

Helicobacter pyloriinfection and gastric cancer: evidence from a retrospective cohort study and nested case-control study in China

, 2002
Run-Tian Wang
openalex   +1 more source