Results 261 to 270 of about 1,389,546 (315)

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

Advanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei, Chunning Li, Lei Zhan, Xiaoyan Li, Yan Hui, Yue Jin, Jing Zhang, Lu Yang, Xin Sun, Xiaoxi Li, Qian Dong, Jingdong Zhang   +11 more
wiley   +1 more source

Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis

Advanced Science, EarlyView.
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu, Qiu Peng, Xiaoyue Zhang, Zhengshuo Li, Yangge Wu, Yuqing Wen, Run Zheng, Shuanglong Wu, Chenfei Zhou, Zhengyu Hu, Lanjun Shu, Xinyi Ma, Qiuyang Li, Ya Ma, Chunlin Ou, Ming Zhao, Songqing Fan, Lingyu Wei, Jian Ma   +18 more
wiley   +1 more source

Suppressive antibiotic therapy for spinal hardware infection: a retrospective cohort study. [PDF]

BMC Infect Dis
Choudhry A, Doub JB, Eke UA.
europepmc   +1 more source

Impact of SGLT2 Inhibitors on Multiple Cardiometabolic Risk Factors: A Retrospective Cohort Study. [PDF]

J Clin Med
Işık H, Demirdöğen KK, Çakır T, Çetinkalp Ş, Kerry Z, Arun MZ.   +5 more
europepmc   +1 more source

Hazelnut oral immunotherapy in children: An Italian single-center retrospective cohort study. [PDF]

Pediatr Allergy Immunol
Barni S, Pessina B, Della Femina S, Catamerò F, Valleriani C, Giovannini M, Liccioli G, Sarti L, Tomei L, Mori F.   +9 more
europepmc   +1 more source

Embolic agents in emergency care: a large retrospective cohort study. [PDF]

CVIR Endovasc
Gargiulo M, Di-Rocco C, Bartoli A, Habert P, Soussan J, Barral PA, Jacquier A, Vidal V, Tradi F.   +8 more
europepmc   +1 more source

Relationship Between ABO/Rh Blood Groups and Knee Osteoarthritis: A Retrospective Cohort Study. [PDF]

J Clin Med
Gumussuyu G, Saritas K, Koctekin B, Gurcan S, Kose O.   +4 more
europepmc   +1 more source

Nursing interventions and multidomain physiological trajectories in ARDS: a retrospective cohort study. [PDF]

Front Med (Lausanne)
Tang Q, Cui K, Zhou J, Ruan Y, Li X.
europepmc   +1 more source